anti-Deoxyribonuclease I-Like 3 (DNASE1L3) Antibodies

DNASE1L3 encodes a member of the deoxyribonuclease I family. Additionally we are shipping DNASE1L3 Kits (16) and DNASE1L3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNASE1L3 1776 Q13609
DNASE1L3 116687 O89107
DNASE1L3 13421 O55070
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Top anti-DNASE1L3 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DNASE1L3 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB DNASE1L3 Antibody (N-term) (ABIN657806) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the DNASE1L3 antibody detected the DNASE1L3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti DNase gamma Polyclonal Antibody, Unconjugated (ABIN872726) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat heart labeled with Rabbit Anti DNase gamma Polyclonal Antibody, Unconjugated (ABIN872726) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: DNASE1L3 Antibody [NBP2-16198] - Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution. Western Blot: DNASE1L3 Antibody [NBP2-16198] - Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

DNASE1L3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against DNASE1L3 Interaction Partners

Human Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. The authors found a significant reduction in serum DNase1l3 level in dermatomyositis/polymyositis and systemic lupus erythematosus, which may associate with clinic features and disease activity.

  2. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1 (show DNASE1 Antibodies), DNASE1L3, and DNASE2 (show DNASE2 Antibodies), possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  3. Data indicate a likely functional variant influencing scleroderma susceptibility at deoxyribonuclease I-like 3 protein DNASE1L3 missense polymorphism rs35677470.

  4. Single nucleotide polymorphisms in the DNASE1L3 is associated with autoimmune diseases.

  5. DNASE1L3 mutations occur in hypocomplementemic urticarial vasculitis syndrome.

  6. These results suggest a cooperative activity between CAD (show CAD Antibodies) and DNAS1L3 to accomplish internucleosomal DNA fragmentation .

  7. We identified a rare autosomal recessive form of systemic lupus erythematosus, in which autozygome analysis revealed a null mutation in the DNASE1L3 gene

  8. investigates the distribution of DNASE1L3 gene SNPs in exons of the gene in eight Asian, three African, and three Caucasian populations worldwide using newly devised genotyping methods.

  9. The Poly(ADP-ribose) polymerase-1 (show PARP1 Antibodies)-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells.

  10. Identification of two functional nuclear localization signals in DNase gamma that have a role in apoptotic DNA fragmentation.

Xenopus laevis Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. Cloning and apoptotic DNase (show DNASE2 Antibodies) activity of Xenopus laevis DNase gamma

Mouse (Murine) Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. DNase1 (show DNASE1 Antibodies) and DNase1 (show DNASE1 Antibodies)-like 3 are independently expressed and thus provide dual host protection against deleterious effects of intravascular neutrophil extracellular traps.

  2. Study reports that DNASE1L3-deficient mice rapidly develop autoantibodies to DNA and chromatin, followed by an systemic lupus erythematosus-like disease. Circulating DNASE1L3 is produced by dendritic cells and macrophages, and its levels inversely correlate with anti-DNA antibody response.

  3. DNase gamma, but not CAD (show CAD Antibodies), is the effector endonuclease for INDF in cells undergoing necrosis.

  4. A comparison of the expression and transport of DNAse1 (show DNASE1 Antibodies) from rats and DNAse1L3 from mice is reported.

  5. These results suggest that DNasegamma provides an alternative mechanism for inducing nuclear changes when the working apoptotic cascade is unsuitable for caspase-activated DNase (show DFFB Antibodies) activation.

  6. serum contains two nucleases, DNase1 (show DNASE1 Antibodies) and DNase1l3, which may substitute or cooperate with each other during DNA degradation, providing effective clearance after exposure or release from dying cells.

DNASE1L3 Antigen Profile

Protein Summary

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with DNASE1L3

  • deoxyribonuclease 1 like 3 (DNASE1L3) antibody
  • deoxyribonuclease 1-like 3 (Dnase1l3) antibody
  • deoxyribonuclease I-like 3 S homeolog (dnase1l3.S) antibody
  • deoxyribonuclease I-like 3 (dnase1l3) antibody
  • Dhp2 antibody
  • dnas1l3 antibody
  • DNasegamma antibody
  • drng-a antibody
  • Lsd antibody
  • MGC64241 antibody
  • MGC76250 antibody
  • MGC89816 antibody
  • SLEB16 antibody

Protein level used designations for DNASE1L3

DNase I homolog protein 2 , DNase I homolog protein DHP2 , DNase I-like 3 , DNase gamma , LS-DNase , Liver and spleen DNase , deoxyribonuclease I-like III , deoxyribonuclease gamma , DNaseY , deoxyribonuclease I-like 3 , deoxyribonuclease 1-like 3 , DNase-gamma , liver and spleen DNase , macrophage specific DNase I

GENE ID SPECIES
1776 Homo sapiens
116687 Rattus norvegicus
379439 Xenopus laevis
394515 Xenopus (Silurana) tropicalis
416008 Gallus gallus
460477 Pan troglodytes
476576 Canis lupus familiaris
512512 Bos taurus
702613 Macaca mulatta
100225960 Taeniopygia guttata
13421 Mus musculus
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