Diacylglycerol Lipase, alpha Proteins (DAGLA)

DAGLA encodes a diacylglycerol lipase. Additionally we are shipping DAGLA Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DAGLA 747 Q9Y4D2
DAGLA 269060 Q6WQJ1
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Top DAGLA Proteins at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 70 to 75 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days

DAGLA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

More Proteins for Diacylglycerol Lipase, alpha (DAGLA) Interaction Partners

Human Diacylglycerol Lipase, alpha (DAGLA) interaction partners

  1. phenotypes associated with rare CNR1 variants are reminiscent of those implicated in the theory of clinical endocannabinoid deficiency syndrome. The severe phenotypes associated with rare DAGLA variants underscore the critical role of rapid 2-AG synthesis and the endocannabinoid system in regulating neurological function and development

  2. In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mRNAs were down-regulated in obese subjects, but the diets had no influence.

  3. PLC-beta1 and DAGL-alpha are detected in discrete brain regions, with a marked predominance of pyramidal morphologies of positive cortical cells.[review]

  4. DAGLalpha mRNA expression is lowest in early life and adulthood, peaking between school age and young adulthood.

  5. This gene was functionally characterized as a diacylglycerol-lipase (DAGL), specifically referred to as DAGL alpha. This enzyme may play a role in the biosynthesis of the endocannbinoid 2-arachidonoylglycerol (2-AG).

Mouse (Murine) Diacylglycerol Lipase, alpha (DAGLA) interaction partners

  1. Results demonstrate that mice with a deletion of the DAGL-alpha enzyme show a phenotype of increased emotional or stress-related behaviors. This is characterized by a reduced exploration of the central area of the open field, a maternal neglect behavior, a fear extinction deficit, increased behavioral despair, increased anxiety-related behaviors in the light/dark box, and reduced hippocampal neurogenesis

  2. Authors demonstrated that phospholipase D and diacylglycerol lipase were required for providing arachidonic acid for prostaglandin E(2) biosynthesis.

  3. In corpus striatum diacylglycerol lipase-alpha activity is regulated by calcium/calmodulin dependent protein kinase (CaMK-II).

  4. Endocannabinoid 2-arachidonoylglycerol produced by DGLalpha, but not by DGLbeta, mediates retrograde suppression at central synapses.

  5. DAGLalpha is the major biosynthetic enzyme for 2-AG in the nervous system and reveal an essential role for this enzyme in regulating retrograde synaptic plasticity and adult neurogenesis.

DAGLA Protein Profile

Protein Summary

This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.

Gene names and symbols associated with DAGLA

  • diacylglycerol lipase alpha (DAGLA)
  • diacylglycerol lipase, alpha (dagla)
  • diacylglycerol lipase, alpha (Dagla)
  • C11orf11 protein
  • DAGL(ALPHA) protein
  • DAGLALPHA protein
  • Nsddr protein

Protein level used designations for DAGLA

diacylglycerol lipase, alpha , neural stem cell-derived dendrite regulator , nsddr , sn1-specific diacylglycerol lipase alpha-like , DGL-alpha , sn1-specific diacylglycerol lipase alpha

426017 Gallus gallus
451241 Pan troglodytes
569398 Danio rerio
100342661 Oryctolagus cuniculus
100385981 Callithrix jacchus
100437303 Pongo abelii
100498478 Xenopus (Silurana) tropicalis
100091533 Ornithorhynchus anatinus
100554568 Anolis carolinensis
747 Homo sapiens
269060 Mus musculus
309207 Rattus norvegicus
483795 Canis lupus familiaris
100520824 Sus scrofa
523665 Bos taurus
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