anti-Dihydropyrimidinase-Like 5 (DPYSL5) Antibodies

DPYSL5 encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Additionally we are shipping Dihydropyrimidinase-Like 5 Kits (15) and Dihydropyrimidinase-Like 5 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DPYSL5 56896 Q9BPU6
DPYSL5 65254 Q9EQF6
DPYSL5 65208 Q9JHU0
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Top anti-Dihydropyrimidinase-Like 5 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Western Blot: CRMP5 Antibody [NBP1-33419] - Sample (30 ug of whole cell lysate) A: H1299 B: Raji 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-33419] - Paraffin-embedded SW480 xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of DPYSL5 expression in transfected 293T cell line by DPYSL5 monoclonal antibody (M02), clone 2G4. Lane 1: DPYSL5 transfected lysate(61.4 KDa). Lane 2: Non-transfected lysate. Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: CRMP5 Antibody [NBP1-85461] - Staining of human lateral ventricle shows strong cytoplasmic and nuclear positivity in neuronal cells. Immunohistochemistry-Paraffin: CRMP5 Antibody  - Staining of human lateral ventricle shows moderate cytoplasmic positivity in neuronal cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Cow Rat Un-conjugated ICC, IF, IHC, IHC (fro), WB Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-3) [ABIN2614984] - Biopsies of deparaffinized Human glioma tissue. Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-3) [ABIN2614984] - Biopsies of deparaffinized Human tonsil tissue. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Cow Rat Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [ABIN2614995] - Biopsies of deparaffinized Human brain tissue. Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [ABIN2614995] - Biopsies of deparaffinized Human glioma tissue. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Mouse Un-conjugated IF, ELISA, WB DPYSL5 monoclonal antibody (M04), clone 2D10. Western Blot analysis of DPYSL5 expression in rat brain. Detection limit for recombinant GST tagged DPYSL5 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using DPYSL5 antibody. 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated IF/ICC, WB Western blot analysis of extracts of various cell lines, using DPYSL5 antibody (ABIN3049350). 100 μL Log in to see 11 to 16 Days
$426.40
Details

DPYSL5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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More Antibodies against Dihydropyrimidinase-Like 5 Interaction Partners

Human Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. Study describes the relevance of DRP5 during osteosarcoma development. DRP5 was upregulated in osteosarcoma specimens and cell lines and shown to function via the downstream MMPs. Inhibition of DRP5 suppressed the growth of cancer cells in vitro and in vivo, and high expression levels of DRP5 were associated with poor prognosis in osteosarcoma patients.

  2. Our findings suggest that CRMP5 serves as a major mediator of Notch (show NOTCH1 Antibodies) signaling and Akt (show AKT1 Antibodies) activation by controlling the degradation of the Notch (show NOTCH1 Antibodies) receptor, with implications for defining a biomarker signature in glioblastoma

  3. present study suggested that CRAM (show CCRL2 Antibodies) could be a clinical prognostic marker for patients with cervical cancer

  4. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  5. identified residues that are crucial for determining the preference for hetero-oligomer or homo-oligomer formation. In spite of being the CRMP family member most closely related to dihydropyrimidinase (show DPYS Antibodies), CRMP-5 does not have amidohydrolase activity.

  6. New CRMP5 isoform present in the nucleus is associated with Glioma.

  7. CRMP-5-IgG defines a paraneoplastic ophthalmological entity of combined optic neuritis and retinitis with vitreous inflammatory cells.

  8. CRMP-5 autoimmune myelopathy and occult neoplasia are important considerations in patients with insidiously progressive myelopathy, especially with known cancer risk.

  9. We describe a patient with optic neuropathy and vitritis as the only clinical manifestations of paraneoplastic optic neuropathy secondary to lung cancer marked by an extremely high titer of CRMP-5 antibody.

  10. findings point at CRMP5 as a novel marker for distinguishing between highly aggressive neuroendocrine carcinoma and the other lung cancers.

Mouse (Murine) Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  2. CRMP5-deficient mice show abnormal Schwann process extension resulting in abnormal cell-axon segregation, indicating that CRMP5 is involved in the morphologic adaptation of Schwann cells to surround axons.

  3. These findings provide the first evidence that CRMP5 is involved in the generation and survival of newly generated neurons in areas of the adult brain with a high level of activity-dependent neuronal plasticity.

  4. Data show that CRMP5 is involved in the development, maintenance and synaptic plasticity of Purkinje cells.

  5. The CRMP5 binding to tubulin (show TUBB Antibodies) modulates CRMP2 (show DPYSL2 Antibodies) regulation of neurite outgrowth and neuronal polarity during brain development.

  6. CRAM regulates filopodial dynamics and growth cone development, thereby restricting the response of growth cone to repulsive guidance cues

  7. In the olfactory bulb, CRMP1 (show CRMP1 Antibodies), CRMP2 (show DPYSL2 Antibodies) and CRMP5 are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.

  8. Our results are therefore consistent with a role for CRMP5 in neuronal process extension.We conclude that expression of CRMP5 is consistent with a dynamic implicit role in forebrain development.

  9. Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1 (show CRMP1 Antibodies), 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.

Dihydropyrimidinase-Like 5 (DPYSL5) Antigen Profile

Protein Summary

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with DPYSL5

  • dihydropyrimidinase like 5 (DPYSL5) antibody
  • Dihydropyrimidinase-related protein 5 (dpyl5) antibody
  • dihydropyrimidinase-like 5a (dpysl5a) antibody
  • dihydropyrimidinase like 5 (dpysl5) antibody
  • dihydropyrimidinase-like 5 (Dpysl5) antibody
  • CRAM antibody
  • CRMP-5 antibody
  • CRMP-5a antibody
  • Crmp5 antibody
  • crmp5.1 antibody
  • DPYSL5 antibody
  • fc28b06 antibody
  • im:7146614 antibody
  • Ulip6 antibody
  • wu:fc28b06 antibody

Protein level used designations for DPYSL5

dihydropyrimidinase-like 5 , dihydropyrimidinase-related protein 5 , Dihydropyrimidinase-related protein 5 , collapsin response mediator protein-5 , dihydropyrimidinase-related protein 5-like , CRMP3-associated molecule , DRP-5 , ULIP-6 , UNC33-like phosphoprotein 6 , collapsin response mediator protein 5

GENE ID SPECIES
483004 Canis lupus familiaris
699648 Macaca mulatta
100126171 Bos taurus
100196759 Salmo salar
100353506 Oryctolagus cuniculus
324416 Danio rerio
100030914 Monodelphis domestica
100071300 Equus caballus
100386950 Callithrix jacchus
100478389 Ailuropoda melanoleuca
100496348 Xenopus (Silurana) tropicalis
100511810 Sus scrofa
100558703 Anolis carolinensis
100598354 Nomascus leucogenys
56896 Homo sapiens
65254 Mus musculus
65208 Rattus norvegicus
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