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anti-Dihydropyrimidinase-Like 5 (DPYSL5) Antibodies

DPYSL5 encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Additionally we are shipping Dihydropyrimidinase-Like 5 Kits (15) and Dihydropyrimidinase-Like 5 Proteins (8) and many more products for this protein.

Gene Name	GeneID	UniProt
DPYSL5	56896	Q9BPU6
DPYSL5	65208	Q9JHU0
DPYSL5	65254	Q9EQF6

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Top anti-Dihydropyrimidinase-Like 5 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2789785	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN443289	Human	Rabbit	Un-conjugated	IHC (p), IHC, WB	0.1 mL	Log in to see	8 to 11 Days	$516.98	Details
ABIN4300550	Human	Rabbit	Un-conjugated	IHC, IHC (p)	0.1 mL	Log in to see	10 to 13 Days	$494.38	Details
ABIN261499	Cow	Rat	Un-conjugated	ICC, IF, IHC, IHC (fro), IHC (p), WB	0.1 mL	Log in to see	7 to 9 Days	$446.35	Details
ABIN261498	Cow	Rat	Un-conjugated	ICC, IF, IHC, IHC (fro), WB	0.1 mL	Log in to see	7 to 9 Days	$446.35	Details
ABIN1872349	Human	Mouse	Un-conjugated	IF, WB	100 μL	Log in to see	11 to 13 Days	$366.77	Details
ABIN961366	Human	Mouse	Un-conjugated	ELISA, WB	100 μg	Log in to see	11 to 14 Days	$537.17	Details
ABIN527992	Human	Mouse	Un-conjugated	IF, ELISA, WB	100 μg	Log in to see	11 to 12 Days	$440.00	Details
ABIN3049349	Human	Mouse	Un-conjugated	IF/ICC, WB	100 μL	Log in to see	11 to 16 Days	$426.40	Details
ABIN950163	Human	Rabbit	Un-conjugated	IP, WB	100 μL	Log in to see	11 to 12 Days	$425.71	Details

More product categories related to Dihydropyrimidinase-Like 5 Antibody

More Antibodies against Dihydropyrimidinase-Like 5 Interaction Partners

Human Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

Study describes the relevance of DRP5 during osteosarcoma development. DRP5 was upregulated in osteosarcoma specimens and cell lines and shown to function via the downstream MMPs. Inhibition of DRP5 suppressed the growth of cancer cells in vitro and in vivo, and high expression levels of DRP5 were associated with poor prognosis in osteosarcoma patients.
Our findings suggest that CRMP5 serves as a major mediator of Notch signaling and Akt activation by controlling the degradation of the Notch receptor, with implications for defining a biomarker signature in glioblastoma
present study suggested that CRAM could be a clinical prognostic marker for patients with cervical cancer
study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.
identified residues that are crucial for determining the preference for hetero-oligomer or homo-oligomer formation. In spite of being the CRMP family member most closely related to dihydropyrimidinase, CRMP-5 does not have amidohydrolase activity.
New CRMP5 isoform present in the nucleus is associated with Glioma.
CRMP-5-IgG defines a paraneoplastic ophthalmological entity of combined optic neuritis and retinitis with vitreous inflammatory cells.
CRMP-5 autoimmune myelopathy and occult neoplasia are important considerations in patients with insidiously progressive myelopathy, especially with known cancer risk.
We describe a patient with optic neuropathy and vitritis as the only clinical manifestations of paraneoplastic optic neuropathy secondary to lung cancer marked by an extremely high titer of CRMP-5 antibody.
findings point at CRMP5 as a novel marker for distinguishing between highly aggressive neuroendocrine carcinoma and the other lung cancers.
patients with CV2/CRMP5-Ab and thymoma developed myasthenic syndrome more frequently

Mouse (Murine) Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

Data show that SRY-box containing gene 5 protein (Sox5) can physically bind to the collapsin response mediator protein 5 (CRMP5) promoter DNA.
study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.
CRMP5-deficient mice show abnormal Schwann process extension resulting in abnormal cell-axon segregation, indicating that CRMP5 is involved in the morphologic adaptation of Schwann cells to surround axons.
These findings provide the first evidence that CRMP5 is involved in the generation and survival of newly generated neurons in areas of the adult brain with a high level of activity-dependent neuronal plasticity.
Data show that CRMP5 is involved in the development, maintenance and synaptic plasticity of Purkinje cells.
The CRMP5 binding to tubulin modulates CRMP2 regulation of neurite outgrowth and neuronal polarity during brain development.
CRAM regulates filopodial dynamics and growth cone development, thereby restricting the response of growth cone to repulsive guidance cues
beyond their signalling function in axon outgrowth and guidance, CRMPs also play a role in mature neurons both in axons and in dendrites
In the olfactory bulb, CRMP1, CRMP2 and CRMP5 are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.
Our results are therefore consistent with a role for CRMP5 in neuronal process extension.We conclude that expression of CRMP5 is consistent with a dynamic implicit role in forebrain development.
Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1, 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.

Dihydropyrimidinase-Like 5 (DPYSL5) Antigen Profile

Protein Summary

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with DPYSL5

dihydropyrimidinase like 5 (DPYSL5) antibody
dihydropyrimidinase-like 5 (Dpysl5) antibody
Dihydropyrimidinase-related protein 5 (dpyl5) antibody
dihydropyrimidinase-like 5a (dpysl5a) antibody
dihydropyrimidinase like 5 (dpysl5) antibody
dihydropyrimidinase like 5 (Dpysl5) antibody
dihydropyrimidinase-like 5b (dpysl5b) antibody

CRAM antibody
CRMP-5 antibody
CRMP-5a antibody
CRMP-5b antibody
Crmp5 antibody
crmp5.1 antibody
crmp5.2 antibody
DPYSL5 antibody
fc28b06 antibody
im:7146614 antibody
si:ch211-152c2.6 antibody
Ulip6 antibody
wu:fc28b06 antibody

Protein level used designations for DPYSL5

CRMP3-associated molecule , DRP-5 , ULIP-6 , UNC33-like phosphoprotein 6 , collapsin response mediator protein 5 , collapsin response mediator protein-5 , dihydropyrimidinase-related protein 5 , dihydropyrimidinase-like 5 , Dihydropyrimidinase-related protein 5 , dihydropyrimidinase-related protein 5-like , collapsin response mediator protein 5.2

GENE ID	SPECIES
56896	Homo sapiens
65208	Rattus norvegicus
65254	Mus musculus
483004	Canis lupus familiaris
699648	Macaca mulatta
100126171	Bos taurus
100196759	Salmo salar
100353506	Oryctolagus cuniculus
324416	Danio rerio
100030914	Monodelphis domestica
100071300	Equus caballus
100386950	Callithrix jacchus
100478389	Ailuropoda melanoleuca
100496348	Xenopus (Silurana) tropicalis
100511810	Sus scrofa
100558703	Anolis carolinensis
100598354	Nomascus leucogenys
100725488	Cavia porcellus
553410	Danio rerio

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