anti-Disabled 2, Mitogen-Responsive Phosphoprotein (DAB2) Antibodies

p59 isoform inhibits growth in prostatic epithelial cells [RGD, Feb 2006]..

list all antibodies Gene Name GeneID UniProt
DAB2 79128 O88797
DAB2 13132 P98078
DAB2    
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Top anti-DAB2 Antibodies at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of p96 on BC3H1 lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of p96. Immunofluorescence staining of Human Fibroblast cells. 50 μg Log in to see 6 to 8 Days
$168.74
Details

DAB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Mouse (Murine)


Human


Top referenced anti-DAB2 Antibodies

  1. Human Monoclonal DAB2 Primary Antibody for IF, IP - ABIN967989 : Hocevar, Smine, Xu, Howe: The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway. in The EMBO journal 2001 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal DAB2 Primary Antibody for IF, IP - ABIN967990 : Mishra, Keyel, Hawryluk, Agostinelli, Watkins, Traub: Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor. in The EMBO journal 2002 (PubMed)
    Show all 4 Pubmed References

More Antibodies against DAB2 Interaction Partners

Mouse (Murine) Disabled 2, Mitogen-Responsive Phosphoprotein (DAB2) interaction partners

  1. The results suggest that Dab2 is required for the excessive calorie-induced differentiation of an adipocyte progenitor cell population that is present in juvenile but depleted in mature animals. The finding provides evidence for a limited pre-adipocyte population in juvenile mammals and the requirement of Dab2 in the regulation of Ras/MAPK (show MAPK1 Antibodies) signal in the commitment of the precursor cells to adipose tissues.

  2. The various novel mechanisms are described by which Dab2 mediates an array of signaling events with vast physiological consequences.

  3. The combination of Arh (show LDLRAP1 Antibodies) and Dab2 is responsible for the majority of adaptor function in LDLR (show LDLR Antibodies) endocytosis and LDLR (show LDLR Antibodies)-mediated cholesterol homeostasis.

  4. cathepsin B (CTSB (show CTSB Antibodies)) inhibition or expression of a CTSB (show CTSB Antibodies)-resistant Dab2 mutant maintains Dab2 expression and shifts long-term TGF-beta (show TGFB1 Antibodies)-treated cells from autophagy to apoptosis

  5. Results identified a novel activation marker, DAB2, which expression is significantly different between microglia activation stages M2a and either M1 or M2b.

  6. these findings reveal that DAB2 is critical for controlling inflammatory signaling during phenotypic polarization of macrophages

  7. Dab2 expression is induced by hormones

  8. Results suggest that endogenous Dab2 exacerbates central nervous system inflammation, potentially acting to up-regulate reactive oxygen species expression in macrophages and microglia, and that it is of potential pathogenic relevance in multiple sclerosis

  9. Disabled-2 is required for efficient hemostasis and platelet activation by thrombin (show F2 Antibodies) in mice.

  10. Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies) are involved in albumin (show ALB Antibodies) endocytosis, and phosphorylation of Dab2 by Akt (show AKT1 Antibodies) induces albumin (show ALB Antibodies) endocytosis in proximal tubule epithelial cells.

DAB2 Antigen Profile

Protein Summary

p59 isoform inhibits growth in prostatic epithelial cells

Gene names and symbols associated with DAB2

  • DAB2, clathrin adaptor protein (Dab2) antibody
  • disabled 2, mitogen-responsive phosphoprotein (Dab2) antibody
  • 5730435J12Rik antibody
  • AA960054 antibody
  • AI957090 antibody
  • D15Wsu122e antibody
  • D630005B22Rik antibody
  • Doc-2 antibody
  • Doc2 antibody
  • p96 antibody

Protein level used designations for DAB2

C9 , DOC-2 p82 isoform , disabled homolog 2 , disabled homolog 2 mitogen-responsive phosphoprotein , mitogen-responsive phosphoprotein

GENE ID SPECIES
79128 Rattus norvegicus
13132 Mus musculus
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