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The product of DLGAP2 is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. Additionally we are shipping Discs, Large (Drosophila) Homolog-Associated Protein 2 Proteins (3) and many more products for this protein.
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Human Polyclonal DLGAP2 Primary Antibody for IHC, ELISA - ABIN1003104
Takeuchi, Hata, Hirao, Toyoda, Irie, Takai: SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. in The Journal of biological chemistry 1997
Show all 4 Pubmed References
Results show that RP11-397D12.4, AC007403.1, and ERICH1-AS1 LncRNA expression are up-regulated in non-small-cell lung cancer (NSCLC) and may be potential biomarkers for predicting the tumorigenesis of NSCLC in the future.
The Gene-based analyses revealed four significant associations in the WT1 (show WT1 Antibodies), ZC3H12C (show ZC3H12C Antibodies), DLGAP2, and GPR1 (show GPR1 Antibodies) genes at p < 0.05. in this study.
DLGAP2 is a susceptible gene of schizophrenia.
this study demonistrated that two SNPs in DLGAP2 (rs6558484 and rs7014992) and prefrontal cortex white matter volume.
DLGAP2 gene is imprinted, with preferential expression from the paternal allele in testis.
Increased expression of PSD-25 and its coassembly with NMDA-receptor subunits NR1 and MR2B in resected epileptic cortical tissue suggest a possible functional role of the complex in in situ epileptogenicity of focal cortical dysplasia.
Semi-quantitative analysis of RNA levels in FMRP (show FMR1 Antibodies) immunoprecipitates showed that in the mouse brain mRNAs encoding PSD (show PSD Antibodies) components, such as Shank1 (show SHANK1 Antibodies), SAPAP1 (show DLGAP1 Antibodies)-3, PSD-95 (show DLG4 Antibodies), and the glutamate (show GRIN1 Antibodies) receptor subunits NR1 (show GRIN1 Antibodies) and NR2B (show GRIN2B Antibodies), are associated with FMRP (show FMR1 Antibodies).
The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified.
discs, large (Drosophila) homolog-associated protein 2
, discs large-associated protein 2
, Disks large-associated protein 2-like
, disks large-associated protein 2-like
, PSD-95/SAP90-associated protein-2
, PSD-95/SAP90-binding protein 2
, SAP90/PSD-95-associated protein 2
, discs large homolog-associated protein 2
, disks large-associated protein 2
, postsynaptic density 95
, SAP90/PSD-95 associated protein 2