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DIRC2 encodes a membrane-bound protein from the major facilitator superfamily of transporters. Additionally we are shipping DIRC2 Kits (6) and DIRC2 Proteins (3) and many more products for this protein.
Showing 10 out of 42 products:
Human Polyclonal DIRC2 Primary Antibody for WB - ABIN1881261
Bodmer, Eleveld, Kater-Baats, Janssen, Janssen, Weterman, Schoenmakers, Nickerson, Linehan, Zbar, van Kessel: Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21). in Human molecular genetics 2002
Show all 2 Pubmed References
Data strongly support the idea that DIRC2 is an electrogenic lysosomal metabolite transporter which is subjected to and presumably modulated by limited proteolytic processing.
Gene disruption may result in haplo-insufficiency and, through this mechanism, in the onset of tumor growth.
This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.
disrupted in renal carcinoma 2
, disrupted in renal carcinoma protein 2 homolog
, Disrupted in renal carcinoma protein 2 homolog
, disrupted in renal carcinoma protein 2-like
, disrupted in renal cancer protein 2
, disrupted in renal carcinoma protein 2
, renal cell carcinoma 4
, disrupted in renal carcinoma 2 homolog