DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Proteins (DNAJB1)

Probably involved in mitochondrial protein import. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Antibodies (324) and DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Kits (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNAJB1 3337 P25685
Rat DNAJB1 DNAJB1 361384  
DNAJB1 81489 Q9QYJ3
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Top DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
Escherichia coli (E. coli) Human GST tag DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) (AA 1-340), (full length) protein (GST tag) 1 mg Log in to see 60 to 71 Days
$1,842.50
Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$313.50
Details
Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$212.50
Details
Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$608.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,918.67
Details

DNAJB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)
,

More Proteins for DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. These studies demonstrate an important role for cellular chaperone Hsp40/DnaJB1 in influenza A virus life cycle by assisting nuclear trafficking of viral ribonucleoproteins.

  2. DNAJB1-PRKACA (show PRKACA Proteins) was evaluated as a key driver of fibrolamellar carcinoma and as a candidate therapeutic target

  3. siRNA experiments confirmed that a reduction in Hsp27 (show HSPB1 Proteins) or Hsp40 rescued CFTR (show CFTR Proteins) in the DeltaF508 mutant, but the rescue was not additive or synergistic with C4 + 18 treatment, indicating these correctors shared a common pathway for rescue

  4. study provides a new molecular mechanism to regulate EGFR (show EGFR Proteins) signaling through modulation of MIG6 (show ERRFI1 Proteins) by DNAJB1 as a negative regulator.

  5. Whole exome sequencing followed by immunohistochemistry of fibrolamellar hepatocellular carcinoma cell lines and tumors showed two structural variants resulting in fusion transcripts: DNAJB1-PRKCA and CLPTM1L-GLIS3.

  6. In this cohort of fibrolamellar hepatocellular carcinoma, almost 80% contained the DNAJB1-PRKACA (show PRKACA Proteins) fusion transcript.

  7. Authors identified DNAJB1 as a negative regulator of PDCD5 (show PDCD5 Proteins)-mediated apoptosis and found that the apoptosis network of PDCD5 (show PDCD5 Proteins) regulates cancer cell death.

  8. We also found that, despite an initial report to the contrary, the human homolog of Sis1, Hdj1, is capable of [PSI+] prion (show PRNP Proteins) propagation in place of Sis1

  9. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.

  10. Studies with specific phosphoantibodies indicate that MK5 (show MAPKAPK5 Proteins) phosphorylates Hsp40/DnaJB1 in vivo at Ser (show SIGLEC1 Proteins)-149 or/and Ser (show SIGLEC1 Proteins)-151 and Ser (show SIGLEC1 Proteins)-171 in the C-terminal domain of Hsp40/DnaJB1.

Fruit Fly (Drosophila melanogaster) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. our data indicate that the MLF/DnaJ-1-dependent increase in Lz level allows the repression of Notch (show NOTCH1 Proteins) expression and signaling to prevent aberrant blood cell development. Thus our findings establish a functional link between MLF and the co-chaperone DnaJ-1 to control RUNX transcription factor activity and Notch (show NOTCH1 Proteins) signaling during blood cell development in vivo.

  2. Additional studies established that the increased toxicity upon mutating UbS2 stems from disrupting the autoprotective role that pathogenic ataxin-3 (show ATXN3 Proteins) has against itself, which depends on the co-chaperone, DnaJ-1. Our data reveal a previously unrecognized balance between pathogenic and potentially therapeutic properties of the ataxin-3 (show ATXN3 Proteins)-Rad23 interaction; they highlight this interaction as critical for the toxicity of the S

  3. Through DnaJ-1, our data connect ataxin-3 (show ATXN3 Proteins) and Rad23 to protective processes involved with protein folding rather than increased turnover of toxic polyQ species.

  4. Expression of DnaJ-1 potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 also leads to reduced toxicity from pathogenic CACNA1A (show CACNA1A Proteins)

  5. HSP40 and HSP110 (show HSPH1 Proteins) function together in protein homeostasis control.

  6. A high positive correlation was found between the levels of Hsp40 expression and scores of basal and induced thermotolerance, implying a significant contribution of Hsp40 gene in thermoadaptation.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) interaction partners

  1. Overexpression of DNAJB1 relieves TDP-43 (show TARDBP Proteins) mediated toxicity in primary rodent cortical neurons.

  2. a biochemical link between Hsp40 expression and Abeta (show APP Proteins)(42) proteostasis that is cell specific

  3. Hsc70, Hdj1 and Hdj2 interact with soluble and fibrillar alpha-synuclein

  4. Hsp40, which was constitutively expressed in postmeiotic spermatogenic cells in testis, was integrated into spermatozoa as two components, that is, sperm head and tail of rodent spermatozoa.

  5. HSP-40 expression was detected after 2 h of heat stress

  6. a role for Hsp40 crosstalk with CSPalpha in neuroprotection.

  7. This is a paper that uses purification techiques to find the following: Hsc40 (show DNAJB5 Proteins), a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 (show HSPA8 Proteins) in mammalian cells.

DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Protein Profile

Protein Summary

Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high- molecular-weight (HMC) complex.

Gene names and symbols associated with DNAJB1

  • DnaJ heat shock protein family (Hsp40) member B1 (DNAJB1)
  • DnaJ heat shock protein family (Hsp40) member B1 (Dnajb1)
  • DnaJ-like-1 (DnaJ-1)
  • DnaJ heat shock protein family (Hsp40) member B1 (dnajb1)
  • DnaJ (Hsp40) homolog 5 (DnaJ-5)
  • type I HSP40 co-chaperone YDJ1 (YDJ1)
  • DnaJ protein (dnaJ)
  • molecular chaperone DnaJ (dnaJ)
  • DnaJ (Hsp40) homolog, subfamily B, member 1a (dnajb1a)
  • 0610007I11Rik protein
  • anon-WO0140519.166 protein
  • anon-WO0172774.135 protein
  • CG10578 protein
  • dhdj-1 protein
  • dhdj1 protein
  • dHDJ1/HSP40 protein
  • Dmel\\CG10578 protein
  • dnaJ protein
  • dnaJ-1 protein
  • DnaJ-5 protein
  • DNAJ1 protein
  • DnaJ1 64EF protein
  • dnajb1 protein
  • dnajb4 protein
  • droj1 protein
  • EU3500 protein
  • hdj1 protein
  • Hsp-40 protein
  • hsp40 protein
  • HSP40/HDJ1 protein
  • hspf1 protein
  • MAS5 protein
  • RSPH16B protein
  • sis1 protein
  • zf-Hsp40 protein
  • zgc:101068 protein

Protein level used designations for DNAJB1

DnaJ (Hsp40) homolog, subfmaily B, member 1 , dnaJ homolog subfamily B member 1 , dnaJ protein homolog 1 , hDj-1 , heat shock 40 kDa protein 1 , heat shock 40kD protein 1 , heat shock protein 40 , human DnaJ protein 1 , radial spoke 16 homolog B , CG10578-PA , CG10578-PB , DnaJ-1-PA , DnaJ-1-PB , Hsp40 , dnaJ like1 , Hsp40 protein , DnaJ protein , DnaJ (Hsp40) homolog, subfamily B, member 1 , DnaJ (Hsp40) homolog, subfamily B, member 1a

GENE ID SPECIES
3337 Homo sapiens
361384 Rattus norvegicus
476688 Canis lupus familiaris
538426 Bos taurus
38643 Drosophila melanogaster
493474 Xenopus (Silurana) tropicalis
692539 Bombyx mori
855661 Saccharomyces cerevisiae S288c
1003643 Staphylococcus aureus subsp. aureus MW2
1473367 Methanosarcina acetivorans C2A
81489 Mus musculus
100713788 Cavia porcellus
445177 Danio rerio
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