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DNAJB4 belongs to the evolutionarily conserved DNAJ/HSP40 protein family.
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These new observations support the idea that HLJ1 is a tumor suppressor candidate and potential biomarker for breast cancer
HLJ1 is an endogenous Src (show SRC Proteins) inhibitor that can suppress cancer metastasis through complex interacting mechanisms.
HLJ1 is a strong tumor suppressor for colorectal carcinoma
Low expression of DNAJB4 is associated with gastric carcinomas.
we combined the Hsp70 (show HSP70 Proteins)-NEF pairs with cochaperones of the J protein family (DnaJA1 (show DNAJA1 Proteins), DnaJA2 (show DNAJA2 Proteins), DnaJB1 (show DNAJB1 Proteins), and DnaJB4) to generate 16 permutations.
Silencing of HLJ1 partially reverses the inhibition of cancer-cell invasion by andrographolide.
HBV could promote HLJ1 expression by up-regulating the transcription factor YY1 (show YY1 Proteins).
acidic stress increases the association between HLJ1 and beta-actin (show ACTB Proteins) to modulate migration of human lung cancer cells
HLJ1 switches the role of NPM1 (show NPM1 Proteins), which can act as tumor suppressor or oncogene (show RAB1A Proteins), by modulating the oligomerization of NPM1 (show NPM1 Proteins) via HLJ1-NPM1 (show NPM1 Proteins) heterodimer formation and recruiting AP-2alpha (show TFAP2A Proteins) to the MMP-2 (show MMP2 Proteins) promoter.
Results indicate that DjA1 (show DNAJA1 Proteins) and DjB4 of subfamilies A and B of human Hsp40 (show DNAJB1 Proteins) have different quaternary structures and chaperone functions.
DNAJB4 belongs to the evolutionarily conserved DNAJ/HSP40 protein family. For background information on the DNAJ family, see MIM 608375.
DnaJ-like heat shock protein 40
, HSP40 homolog
, dnaJ homolog subfamily B member 4
, heat shock 40 kDa protein 1 homolog
, heat shock protein 40 homolog
, human liver DnaJ-like protein
, DnaJ (Hsp40) homolog, subfamily B, member 4-like
, DnaJ (Hsp40) homolog, subfamily B, member 4
, DnaJ homolog subfamily B member 4
, DNAj homolog subfamily B member 4
, dnaJ homolog subfamily B member 4-like