DNAJB4 Protein (Myc-DYKDDDDK Tag)
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- Target See all DNAJB4 Proteins
- DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DNAJB4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DNAJB4 / HSP40 homolog protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DNAJB4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))
- Alternative Name
- Dnajb4,hsp40 Homolog (DNAJB4 Products)
- Synonyms
- DNAJW Protein, DjB4 Protein, HLJ1 Protein, 1700029A20Rik Protein, 2010306G19Rik Protein, 5730460G06Rik Protein, zgc:91922 Protein, dnajb4 Protein, MGC83507 Protein, DNAJB4 Protein, DKFZp469B0618 Protein, DnaJ heat shock protein family (Hsp40) member B4 Protein, DnaJ (Hsp40) homolog, subfamily B, member 4 Protein, DnaJ heat shock protein family (Hsp40) member B4 S homeolog Protein, DnaJ homolog subfamily B member 4 Protein, putative dnaj homolog subfamily B member 4 Protein, DNAJB4 Protein, Dnajb4 Protein, dnajb4 Protein, dnajb4.S Protein, Bm1_16640 Protein, Smp_020920.1 Protein
- Background
- The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 37.6 kDa
- NCBI Accession
- NP_008965
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