anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) Antibodies

DNAJB6 encodes a member of the DNAJ protein family. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily B, Member 6 Proteins (17) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNAJB6 10049 O75190
DNAJB6 23950 O54946
DNAJB6 362293 Q6AYU3
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 6 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DNAJB6 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Muscle 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image DNAJB6 antibody [N3C3] detects DNAJB6 protein at nucleus by immunofluorescent analysis. Sample: NT2D1 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: DNAJB6 protein stained by DNAJB6 antibody [N3C3] , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. WB Image Sample (30 ug of whole cell lysate) A: U87-MG 12% SDS PAGE antibody diluted at 1:500 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram) using DNAJB6  Antibody , followed by FITC-conjugated goat-anti-rabbit secondary antibodies. Immunohistochemistry analysis in human brain tissue (Formalin-fixed, Paraffin-embedded) using DNAJB6  Antibody , followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated. 0.4 mL 6 to 8 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using DNAJB6 antibody (ABIN5974242) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human well-differentiated squamous skin carcinoma using DNAJB6 antibody (ABIN5974242) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB Anti-DNAJB6 / DnaJ antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using DNAJB6 antibody. Immunohistochemistry of paraffin-embedded human well-differentiated squamous skin carcinoma using DNAJB6 antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using DNAJB6 antibody. Immunohistochemistry of paraffin-embedded human well-differentiated squamous skin carcinoma using DNAJB6 antibody at dilution of 1:100 (x400 lens). 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to DNAJB6 on HeLa cell. [antibody concentration 10 ug/ml] DNAJB6 monoclonal antibody (M01), clone 2C11-C1 Western Blot analysis of DNAJB6 expression in Jurkat . 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of DNAJB6 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in Hela cell line lysate. DNAJB6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 6 Antibodies

  1. Human Polyclonal DNAJB6 Primary Antibody for IF, WB - ABIN523418 : Mitra, Rostas, Dyess, Shevde, Samant: Micro-RNA-632 downregulates DNAJB6 in breast cancer. in Laboratory investigation; a journal of technical methods and pathology 2012 (PubMed)

  2. Human Monoclonal DNAJB6 Primary Antibody for IF, ELISA - ABIN564339 : De Bock, Lin, Mekkawy, Byrne, Wang: Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion. in International journal of oncology 2010 (PubMed)

  3. Human Polyclonal DNAJB6 Primary Antibody for ICC, IF - ABIN4305595 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

  4. Chlamydomonas reinhardtii (C. reinhardtii) Polyclonal DNAJB6 Primary Antibody for WB - ABIN1027728 : Pellecchia, Szyperski, Wall, Georgopoulos, Wüthrich: NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone. in Journal of molecular biology 1996 (PubMed)
    Show all 4 Pubmed References

More Antibodies against DnaJ (Hsp40) Homolog, Subfamily B, Member 6 Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) interaction partners

  1. Our two cases lie within the phenotypic spectrum of previously reported LGMD1D phenotypes. Additionally, our native Saudi Bedouin patients harbored a mutation c.C287T (p.P96L) in the DNAJB6 gene.

  2. DnaJB6 binds to smaller polyQ aggregates to block their toxicity.

  3. Our report confirms that some DNAJB6 mutations cause distal-onset myopathy and hence DNAJB6 defects should be considered broadly in dominant muscular dystrophy families.

  4. DNAJB6 is a central and versatile player in the protein aggregation and degradation system.DNAJB6 protein keeps Parkin C289G mutant protein in a soluble, degradation-competent form.

  5. This study expands the molecular spectrum of DNAJB6 mutations and also emphasizes the pathogenic role of DNAJB6 dysfunction in distal-onset myopathy.

  6. Expression of the heat shock protein DNAJB6/MRJ was elevated in neutrophils and lymphocytes of patients with atopic dermatitis compared with healthy donors. The highest level of the DNAJB6/MRJ protein was found to be in neutrophils at acute phase of severe atopic dermatitis and gradually decline as continue to the disease.

  7. mRNA levels of HSP family members (HSP70B', HSP72, HSP40/DNAJ, and HSP20/CRYAB) are upregulated by the intracellular MMP3 overload.

  8. the cytoprotective effects of DNAJB6(S) may be mediated, at least in part, by the mitochondrial pathway of apoptosis.

  9. The results indicate both genetic and physical interactions between disease-linked RNA-binding proteinss and DNAJB6/mrj, suggesting etiologic overlap between the pathogenesis of adult-onset inherited myopathies initiated by mutations in hnRNPA2B1 and DNAJB6.

  10. LGMD1D mutations in DNAJB6 disrupt its sarcoplasmic function suggesting a role for DNAJB6b in Z-disc organization and stress granule kinetics.

  11. DNAJB6 mutations p.F91I and p.F91L show a significant reduction of the anti-aggregation function compared to the wild-type and p.F93L mutation

  12. Functional study using zebrafish embryos demonstrated that p.Phe91Leu elicits more severe muscle defects than the reported p.Phe93Leu and p.Pro96Arg mutations

  13. DnaJB6-protected yeast cells from polyglutamine toxicity and cured yeast of both [URE3] prions and weak variants of [PSI(+)] prions but not strong [PSI(+)] prions

  14. This study showed that Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy.

  15. DNAJB6a reduces AKT signaling, and DNAJB6 expression in cancer cells reduces their proliferation and growth of xenograft esophageal squamous cell tumors in mice.

  16. There was a positive correlation between DNAJB6 and IQGAP1 expression.

  17. Geneticanalysis indicated a heterozygous missense mutation of c.279C>G

  18. Findings suggest a novel function of HSP70/MRJ/uPAR complex in cell adhesion, invasion and migration, and may provide more understanding in the mechanisms of uPAR-mediated cancer metastasis.

  19. DNAJB6 G/F domain mutants disrupt the processing of nuclear TDP-43 stress granules in mammalian cells.

  20. DNAJB6 interacts with growing amyloid-beta 42 (Abeta42) aggregates, which leads to sub-stoichiometric inhibition of amyloid formation

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) interaction partners

  1. Mrj(-/-) chorions at embryonic day 8.5 have expanded Rhox4b expression domains and do not form normal layers of gene expression suggesting that chorion patterning requires Mrj.

  2. Data show that Mrj(-/-) embryos exhibit neural tube defects independent of the placenta phenotype, including exencephaly and thin-walled neural tubes, and suggest that Mrj plays an important role in neural stem cell self-renewal.

  3. NFATc3 is negatively regulated by class II histone deacetylases through the DnaJ (heat shock protein-40) superfamily member Mrj

  4. Study demonstrates here that, in the developing placenta of the mouse, the absence of the Mrj co-chaperone prevents proteasome degradation of keratin 18 intermediate filaments, resulting in the formation of keratin inclusion bodies.

  5. DnaJB6 is necessary for translocation of Slfn1 into the nucleus, where Slfn1 down-regulates cyclin D1, induces cell-cycle arrest and programmes a quiescent state of T-cells

DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) Antigen Profile

Protein Summary

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants\; however, not all variants have been fully described.

Gene names and symbols associated with DNAJB6

  • DnaJ heat shock protein family (Hsp40) member B6 (DNAJB6) antibody
  • DnaJ heat shock protein family (Hsp40) member B6 (Dnajb6) antibody
  • DnaJ (Hsp40) homolog, subfamily B, member 6b (dnajb6b) antibody
  • DnaJ heat shock protein family (Hsp40) member B6 S homeolog (dnajb6.S) antibody
  • DnaJ heat shock protein family (Hsp40) member B6 L homeolog (dnajb6.L) antibody
  • DJ4 antibody
  • DnaJ antibody
  • dnajb6 antibody
  • HHDJ1 antibody
  • HSJ-2 antibody
  • hsj2 antibody
  • LGMD1E antibody
  • mDj4 antibody
  • Mrj antibody
  • MSJ-1 antibody
  • zgc:56709 antibody

Protein level used designations for DNAJB6

DnaJ-like 2 protein , dnaJ homolog subfamily B member 6 , heat shock protein J2 , HSJ-2 , mammalian relative of DnaJ , MRJ , MSJ-1 , hsp40 homolog , DnaJ (Hsp40) homolog, subfamily B, member 6 , dnaJ homolog subfamily B member 6-B

GENE ID SPECIES
10049 Homo sapiens
23950 Mus musculus
362293 Rattus norvegicus
393275 Danio rerio
420448 Gallus gallus
282215 Bos taurus
608937 Canis lupus familiaris
495138 Xenopus laevis
100174558 Pongo abelii
734291 Xenopus laevis
100713928 Cavia porcellus
Selected quality suppliers for anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) Antibodies
Did you look for something else?