anti-Doublecortin Domain Containing 2 (DCDC2) Antibodies

DCDC2 encodes a doublecortin domain-containing family member. Additionally we are shipping DCDC2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCDC2 51473 Q9UHG0
DCDC2 291130 D3ZR10
DCDC2    
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Top anti-DCDC2 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DCDC2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-DCDC2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185538 (0.2µg/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Dcdc2a Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Mouse Brain WB Suggested Anti-Dcdc2a  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Goat Un-conjugated ELISA, WB Staining of mouse brain lysate (35µg protein in RIPA buffer) with A) EB07463 (0.1µg/ml) and B) ABIN185538. Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: DCDC2 Antibody [NBP1-84298] - Staining of human pancreas shows distinct positivity in intercalated ducts. Immunocytochemistry/Immunofluorescence: DCDC2 Antibody [NBP1-84298] - Staining of human cell line U-2 OS shows positivity in cytoskeleton (intermediate filaments). 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Goat Un-conjugated ELISA 100 μg Log in to see 11 to 14 Days
$610.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DCDC2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated WB DCDC2 Antibody (Center)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DCDC2 antibody detected the DCDC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details

Top referenced anti-DCDC2 Antibodies

  1. Human Polyclonal DCDC2 Primary Antibody for IF (p), IHC (p) - ABIN1385734 : Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016 (PubMed)

  2. Human Polyclonal DCDC2 Primary Antibody for ELISA, IHC - ABIN251255 : Cope, Harold, Hill, Moskvina, Stevenson, Holmans, Owen, ODonovan, Williams: Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. in American journal of human genetics 2005 (PubMed)

  3. Human Polyclonal DCDC2 Primary Antibody for ELISA, WB - ABIN547772 : McGrath, Smith, Pennington: Breakthroughs in the search for dyslexia candidate genes. in Trends in molecular medicine 2006 (PubMed)

  4. Human Polyclonal DCDC2 Primary Antibody for ICC, IF - ABIN4304490 : Jeruschke, Jeruschke, DiStasio, Karaterzi, Büscher, Nalbant, Klein-Hitpass, Hoyer, Weiss, Stottmann, Weber: Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression. in PLoS ONE 2015 (PubMed)

More Antibodies against DCDC2 Interaction Partners

Human Doublecortin Domain Containing 2 (DCDC2) interaction partners

  1. Worldwide distribution of the DCDC2 READ1 regulatory element and its relationship with phoneme variation across languages.

  2. Downregulation of microRNA-645 suppresses breast cancer cell metastasis via targeting DCDC2

  3. By suggesting the presence of common biological processes underlying reading (dis)ability, these findings represent initial support for a generalist effect of the non-additive interdependence between READ1 and the KIAA0319 risk haplotype and can help in clinically assessing the individual risk for Developmental dyslexia.

  4. Neonatal sclerosing cholangitis patients in substantial proportion harbour mutations in DCDC2.

  5. Study concludes that DCDC2 deletion is not a strong risk factor for dyslexia.

  6. The study corroborates the importance of rs7765678-DCDC2 among others in the aetiology of dyslexia in a German case-control cohort.

  7. Study identified biallelic missense mutations or in-frame deletion in DCDC2 in children affected with neonatal sclerosi. Mutations involve highly conserved amino acids in the doublecortin domains of the protein. In cholangiocytes, DCDC2 protein is normally located in the cytoplasm and cilia, whereas in patients the mutated protein is accumulated in the cytoplasm, absent from cilia, and associated with ciliogenesis defect.

  8. Developmental dyslexia genetic (DCDC2) and environmental factors (smoke and miscarriage) underlie ADHD traits supporting a potential pleiotropic effect.

  9. that endogenous DYX1C1 localizes to the base of the cilium, whereas DCDC2 localizes along the entire axoneme of the cilium

  10. DCDC2 Polymorphism is associated with reading disability.

  11. off-target, non-immune mediated effects of the mTOR-inhibitor everolimus on the podocyte cytoskeleton might involve regulation of microtubules, revealing a potential novel role of TUBB2B and DCDC2 in glomerular podocyte development

  12. This study demonstrated that DCDC2 intron 2 deletion impair illusory visual motion perception-specifically processed by the magnocellular-dorsal (M-D) stream-is impaired in children with Developmental dyslexia.

  13. A nonsynonymous polymorphism in DCDC2 (corrected P = 0.002) and a noncoding variant in S100B (corrected P = 0.016) showed a significant association with spelling performance in families of German origin.

  14. Our results reveal DCDC2a to be a deafness gene and a player in hair cell kinocilia and supporting cell primary cilia length regulation likely via its role in microtubule formation and stabilization.

  15. the association of DCDC2 and KIAA0319 with Developmental dyslexia in Chinese population should be further validated

  16. In a population carrying a deletion in the DCDC2 gene, impaired motion perception was identified in subjects with dyslexia.

  17. DCDC2d is associated with altered fractional anisotropy

  18. Among children exposed to low socioeconomic level, READ1 [regulatory element associated with dyslexia 1 ] genetic variant targets the worst outcome in children's attention.

  19. DCDC2 interacts with the mediator of Wnt signaling dishevelled, and that DCDC2 overexpression inhibits beta-catenin-dependent Wnt signaling; central role of Wnt signaling in the pathogenesis of nephronophthisis-related ciliopathies

  20. An SNP in DCDC2 (rs793842) was significantly associated with the thickness of the left temporoparietal cortex.

DCDC2 Antigen Profile

Protein Summary

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with DCDC2

  • doublecortin domain containing 2 (DCDC2) antibody
  • doublecortin domain containing 2 (Dcdc2) antibody
  • doublecortin domain containing 2B (dcdc2b) antibody
  • DCDC2 antibody
  • DCDC2A antibody
  • RU2 antibody
  • RU2S antibody
  • zgc:123267 antibody

Protein level used designations for DCDC2

doublecortin domain-containing protein 2 , doublecortin domain containing 2 , doublecortin domain-containing protein 2-like , LOW QUALITY PROTEIN: doublecortin domain-containing protein 2

GENE ID SPECIES
51473 Homo sapiens
291130 Rattus norvegicus
472225 Pan troglodytes
563259 Danio rerio
707472 Macaca mulatta
100352162 Oryctolagus cuniculus
100412921 Callithrix jacchus
488244 Canis lupus familiaris
100017769 Monodelphis domestica
100052480 Equus caballus
100297854 Bos taurus
100723535 Cavia porcellus
Selected quality suppliers for anti-DCDC2 (DCDC2) Antibodies
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