anti-Doublecortin Domain Containing 2 (DCDC2) Antibodies

DCDC2 encodes a doublecortin domain-containing family member. Additionally we are shipping DCDC2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCDC2 51473 Q9UHG0
DCDC2 291130 D3ZR10
DCDC2 195208 Q5DU00
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Top anti-DCDC2 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-DCDC2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Hela cell lysate WB Suggested Anti-DCDC2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185538 (0.2µg/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-Dcdc2a Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Mouse Brain WB Suggested Anti-Dcdc2a <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Goat Un-conjugated ELISA, WB Staining of mouse brain lysate (35µg protein in RIPA buffer) with A) EB07463 (0.1µg/ml) and B) ABIN185538. Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: DCDC2 Antibody [NBP1-84298] - Staining of human pancreas shows distinct positivity in intercalated ducts. Immunocytochemistry/Immunofluorescence: DCDC2 Antibody [NBP1-84298] - Staining of human cell line U-2 OS shows positivity in cytoskeleton (intermediate filaments). 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Goat Un-conjugated ELISA 100 μg Log in to see 7 to 9 Days
$610.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DCDC2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated WB DCDC2 Antibody (Center)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DCDC2 antibody detected the DCDC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details

Top referenced anti-DCDC2 Antibodies

  1. Human Polyclonal DCDC2 Primary Antibody for IF (p), IHC (p) - ABIN1385734 : Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016 (PubMed)

  2. Mouse (Murine) Polyclonal DCDC2 Primary Antibody for ELISA, WB - ABIN251687 : McGrath, Smith, Pennington: Breakthroughs in the search for dyslexia candidate genes. in Trends in molecular medicine 2006 (PubMed)

  3. Human Polyclonal DCDC2 Primary Antibody for ELISA, IHC - ABIN251255 : Cope, Harold, Hill, Moskvina, Stevenson, Holmans, Owen, ODonovan, Williams: Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. in American journal of human genetics 2005 (PubMed)

  4. Human Polyclonal DCDC2 Primary Antibody for ICC, IF - ABIN4304490 : Jeruschke, Jeruschke, DiStasio, Karaterzi, Büscher, Nalbant, Klein-Hitpass, Hoyer, Weiss, Stottmann, Weber: Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression. in PLoS ONE 2015 (PubMed)

More Antibodies against DCDC2 Interaction Partners

Human Doublecortin Domain Containing 2 (DCDC2) interaction partners

  1. Worldwide distribution of the DCDC2 READ1 regulatory element and its relationship with phoneme variation across languages.

  2. Downregulation of microRNA-645 suppresses breast cancer cell metastasis via targeting DCDC2

  3. By suggesting the presence of common biological processes underlying reading (dis)ability, these findings represent initial support for a generalist effect of the non-additive interdependence between READ1 and the KIAA0319 (show KIAA0319 Antibodies) risk haplotype and can help in clinically assessing the individual risk for Developmental dyslexia.

  4. Neonatal sclerosing cholangitis patients in substantial proportion harbour mutations in DCDC2.

  5. Study concludes that DCDC2 deletion is not a strong risk factor for dyslexia.

  6. The study corroborates the importance of rs7765678-DCDC2 among others in the aetiology of dyslexia in a German case-control cohort.

  7. Study identified biallelic missense mutations or in-frame deletion in DCDC2 in children affected with neonatal sclerosi. Mutations involve highly conserved amino acids in the doublecortin (show DCX Antibodies) domains of the protein. In cholangiocytes, DCDC2 protein is normally located in the cytoplasm and cilia, whereas in patients the mutated protein is accumulated in the cytoplasm, absent from cilia, and associated with ciliogenesis defect.

  8. Developmental dyslexia genetic (DCDC2) and environmental factors (smoke and miscarriage) underlie ADHD traits supporting a potential pleiotropic effect.

  9. that endogenous DYX1C1 (show DYX1C1 Antibodies) localizes to the base of the cilium, whereas DCDC2 localizes along the entire axoneme of the cilium

  10. DCDC2 Polymorphism is associated with reading disability.

Mouse (Murine) Doublecortin Domain Containing 2 (DCDC2) interaction partners

  1. Behavioral results revealed deficits in rapid auditory processing, working memory and reference memory in Dcdc2(del2/del2) mice when compared with matched wild types.

  2. Results link the function of the dyslexia-associated gene Dcdc2 to spike timing through activity of N-methyl-D-aspartate receptor (show GRIN1 Antibodies) (NMDAR (show GRIN1 Antibodies))

  3. These results indicate that Dcdc2 is not required for neurogenesis, neuronal migration or differentiation in mice, but may have partial functional redundancy with doublecortin (show DCX Antibodies).

  4. heterozygous and homozygous mutations of Dcdc2 result in persistent visuo-spatial memory deficits, as well as visual discrimination and long-term memory deficits

DCDC2 Antigen Profile

Protein Summary

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with DCDC2

  • doublecortin domain containing 2 (DCDC2) antibody
  • doublecortin domain containing 2B (dcdc2b) antibody
  • doublecortin domain containing 2 (Dcdc2) antibody
  • doublecortin domain containing 2a (Dcdc2a) antibody
  • AW492955 antibody
  • Dcdc2 antibody
  • DCDC2A antibody
  • RU2 antibody
  • RU2S antibody
  • zgc:123267 antibody

Protein level used designations for DCDC2

doublecortin domain containing 2 , doublecortin domain-containing protein 2 , doublecortin domain-containing protein 2-like

GENE ID SPECIES
100052480 Equus caballus
472225 Pan troglodytes
563259 Danio rerio
707472 Macaca mulatta
100352162 Oryctolagus cuniculus
100412921 Callithrix jacchus
100017769 Monodelphis domestica
51473 Homo sapiens
291130 Rattus norvegicus
488244 Canis lupus familiaris
100297854 Bos taurus
195208 Mus musculus
Selected quality suppliers for anti-DCDC2 (DCDC2) Antibodies
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