anti-E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) Antibodies

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Additionally we are shipping ELF3 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ELF3 13710 Q3UPW2
ELF3 304815 Q4V7E1
ELF3 1999 P78545
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Top anti-ELF3 Antibodies at antibodies-online.com

Showing 10 out of 125 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Elf3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: MCF7 cell lysate Elf3 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC, WB Mouse Stomach WB Suggested Anti-Elf3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Trachea 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Elf3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  SP2/0 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Elf3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Trachea 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184777 staining (3µg/ml) of NCI-H460 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ELF3 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Thymus 100 μL 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ELF3 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using ESE1 , antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using ESE1, antibody at 1:500 dilution. 100 μL 3 to 4 Days
$466.18
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

Top referenced anti-ELF3 Antibodies

  1. Human Polyclonal ELF3 Primary Antibody for ELISA, WB - ABIN249576 : Kohno, Okamoto, Ishibe, Nagayama, Shima, Nishijo, Shibata, Fukiage, Otsuka, Uejima, Araki, Naka, Nakashima, Aoyama, Nakayama, Nakamura, Toguchida: Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal ELF3 Primary Antibody for ICC, IF - ABIN153155 : Ghassemifar, Redmond, Zainuddin, Chirila: Advancing towards a tissue-engineered tympanic membrane: silk fibroin as a substratum for growing human eardrum keratinocytes. in Journal of biomaterials applications 2010 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) Polyclonal ELF3 Primary Antibody for IHC, WB - ABIN2779832 : Do, Song, Yang, Kim, Kim, Kim, Cha, Chung, Kim: Identification of multiple nuclear localization signals in murine Elf3, an ETS transcription factor. in FEBS letters 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ELF3 Interaction Partners

Mouse (Murine) E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) interaction partners

  1. ELF3 controls LCN2 expression in cooperation with NFkappaB.

  2. a novel role for ELF3 as a procatabolic factor that may contribute to cartilage remodeling and degradation by regulating MMP13 gene transcription.

  3. A novel function of Elf3 is identified that defines allergic airway inflammation caused by the regulation of dendritic cell-driven T helper (Th)1 cell, Th2 cell, and Th17 cell differentiation.

  4. Elf3 plays an important role in the regulation of lung cell proliferation and differentiation during repair of the injured bronchiolar airway epithelium.

  5. ESE-1 is an Ang II-inducible transcription factor that plays an important counter-regulatory role in the setting of vascular inflammation and remodeling.

  6. Elf3 amino acid residues within the flanking region, including Trp361, are important for the structural integrity of the protein as well as for the Efl3 DNA binding and transactivation activity.

  7. Like other Ets-family members, Elf3 functions as a sequence-specific DNA-binding transcriptional factor

  8. Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 for the terminal differentiation of absorptive enterocytes.

  9. Evidence that mElf-3, a member of the Ets family, plays a key role in the activation of the mTbetaR-II promoter.

  10. ErbB2 activation of ESX gene expression

  11. Both proximal and distal regions that regulate Elf3 promoter activity were identified.

  12. Elf3 contains multiple NLS motifs, which may function cooperatively to effect efficient nuclear transport

Human E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) interaction partners

  1. ELF3 knockdown reversed epithelial-mesenchymal transition via repressing ZEB1 expression through miR-141-3p upregulation.

  2. We observed association of low ELF3 expression with increased risk and overall poor survival using publicly available data. ELF3-modulated reversal of EMT might be a useful strategy in the treatment of bladder cancer.

  3. Study found that overexpression of ESE-1 suppressed tumorigenicity in a xenograft mouse, and repressed anchorage-independent growth and migration/invasion in human colon cancer cells. ESE-1 localized abundantly in the nucleus, and internal deletion of nuclear localization sequence 2 reduced nuclear ESE-1 particularly the three lysine residues (318-320). These data suggest that ESE-1 is a tumor suppressor in colon cancer.

  4. ELF3 was demonstrated to form a positive feedback loop with MAPK pathways.

  5. Low ESE1 expression is associated with Nonsmall cell lung cancer.

  6. Data suggest that ELF3 is up-regulated at mRNA and protein levels in NSCLC (non-small cell lung cancer) tissues compared to corresponding control lung tissue; expression level of ELF3 is correlated with overall survival of patients with NSCLC.

  7. Leptin synergizes with IL-1beta in inducing ELF3 expression in chondrocytes.

  8. Data proved the direct binding of miR-320a-3p on the 3'UTR region of ELF3 mRNA in non-small cell lung cancer cells, causing the decreasing expression of ELF3 transcriptionally.

  9. Data suggest ESE-1 silencing as a mean to treat HER2(+) patients who show resistance to anti-HER2 therapy.

  10. These findings position RIPK4 upstream of a hierarchal IRF6-GRHL3-ELF3 transcription factor pathway in keratinocytes.

  11. Epithelium-specific ETS transcription factor 1 (ESE1), a member of the Ets transcription factor family.

  12. ELF3 interacts directly with the HMG domain of Sox9. Importantly, overexpression of ELF3 significantly decreased Sox9/CBP-dependent HAT activity.

  13. Data indicate that the transcription factor E74-like factor 3 (ELF3) was one of the genes whose expression was upregulated in microdissected ovarian cancer cells of long-term survivors.

  14. Survival analysis showed that the non-small cell lung carcinoma patients with enhanced expression of CK7, ELF3, EGFR, and EphB4 mRNA in peripheral blood leukocytes had poorer disease-free survival and overall survival than those without.

  15. data suggest that interactions between ESE1 and beta-/alpha-catenins might be a mechanism by which the ESE1 protein determines the beta-catenin function and tumorigenesis

  16. ELF3 is a frequently mutated tumor suppressor gene of periampullary tumors.

  17. ELF3 is a novel transcriptional repressor of estrogen receptor alpha in breast cancer cells.

  18. suggest that ESE-1 may play a role in regulating airway inflammation by regulating ICAM-1 expression

  19. our data suggested that ESE1/ELF3 may promote the UC progression via accelerating NF-kappaB activation and thus facilitating IEC apoptosis.

  20. data suggest that polyomavirus enhancer activator 3 and epithelium-specific transcription factor-1 may play important roles in pluri potent and tumorigenic embryonic carcinoma cells.

ELF3 Antigen Profile

Protein Summary

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Gene names and symbols associated with ELF3

  • E74 like ETS transcription factor 3 (elf3) antibody
  • E74-like factor 3 (Elf3) antibody
  • E74 like ETS transcription factor 3 (Elf3) antibody
  • E74 like ETS transcription factor 3 (ELF3) antibody
  • EPR-1 antibody
  • ERT antibody
  • ESE-1 antibody
  • ESX antibody
  • jen antibody

Protein level used designations for ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific) , ETS-related transcription factor Elf-3 , epithelial-restricted with serine box , epithelium-restricted Ets protein ESX , epithelium-specific Ets transcription factor 1 , E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific) , E74-like factor 3 (ets domain transcription factor) , ets domain transcription factor, serine box (epithelial-specific)

GENE ID SPECIES
100144720 Xenopus (Silurana) tropicalis
13710 Mus musculus
304815 Rattus norvegicus
1999 Homo sapiens
508503 Bos taurus
490235 Canis lupus familiaris
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