EDARADD ELISA Kits
EDARADD was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands.
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EDARADD Antigen Profile
Protein Summary
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Gene names and symbols associated with EDARADD
- EDAR (ectodysplasin-A receptor)-associated death domain (Edaradd) antibody
- EDAR associated death domain (EDARADD) antibody
- 1810032E07Rik antibody
- 5830469M23Rik antibody
- A630043P06 antibody
- cr antibody
- ECTD11A antibody
- ECTD11B antibody
- ED3 antibody
- EDA3 antibody
Protein level used designations for EDARADD
EDAR-associated death domain protein , crinkled , ectodysplasin-A receptor-associated adapter protein , crinkled homolog , ectodysplasia A receptor associated death domain , ectodysplasin A receptor associated adapter protein
| GENE ID | SPECIES |
|---|---|
| 171211 | Mus musculus |
| 128178 | Homo sapiens |
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