Early B-Cell Factor 1 Proteins (EBF1)

Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.. Additionally we are shipping EBF1 Antibodies (52) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EBF1 13591 Q07802
EBF1 1879 Q9UH73
Rat EBF1 EBF1 116543 Q63398
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Top EBF1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days

EBF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
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More Proteins for Early B-Cell Factor 1 (EBF1) Interaction Partners

Mouse (Murine) Early B-Cell Factor 1 (EBF1) interaction partners

  1. EBF1 heterozygosity resulted in the deregulation of at least eight transcription factors involved in lymphopoiesis and the deregulation of key proteins playing crucial roles in survival, development, and differentiation of pro-B lymphocytes.

  2. Down-regulation of EBF1 (and EBF2) genes leads to a severe impairment of myelin formation in Schwann cells.

  3. The authors show that transcription factors Lhx2 and Ebf specify olfactory receptor enhancers by binding in a functionally cooperative fashion to stereotypically spaced motifs that defy heterochromatin.

  4. the interaction of the CCR4-NOT complex with EBF1 diversifies the function of EBF1 in a context-dependent manner and may coordinate transcriptional and post-transcriptional gene regulation.

  5. C-terminal domain enables permissive B cell lineage-specific changes in progenitor chromatin

  6. Pax5 and Ebf1 collaborate to modulate the transcriptional response to Notch signaling, and their combined heterozygous loss allows for T-lineage conversion of B cell progenitors.

  7. a dramatic increase in the frequency of pro-B cell leukemia was observed in mice with combined heterozygous mutations in the Ebf1 and Pax5 genes, revealing a synergistic effect of combined dose reduction of these proteins

  8. EBF1 is an important regulator of adipose morphology and fat cell lipolysis and may constitute a link between White adipose tissue inflammation, altered lipid metabolism, adipose hypertrophy, and insulin resistance.

  9. Ebf1 has a significant and novel role in glomerular development, podocyte maturation, and the maintenance of kidney integrity and function.

  10. Our results suggest that Bach2 functions with Bach1 and EBF1 to promote B cell development by repressing myeloid genes in common lymphoid progenitor cells

  11. EBF1 functions as a key integrator of signal transduction, inflammation, and metabolism

  12. Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

  13. Ebf1 and c-Myb antagonize Rag transcription by negatively regulating the binding of Foxo1 to the Rag locus.

  14. EBF1 expression in committed pro-B cells suppresses T cell and innate lymphoid cell portential.

  15. transcription factor EBF1 promotes B cell lineage commitment by directly repressing expression of the T-cell-lineage-requisite Gata3 gene.

  16. the interplay between Zfp521 and Ebf1 is identified as a novel rheostat for bone homeostasis.

  17. Ebf1 is one of the few transcription factors inhibiting osteoblast differentiation in a non cell-autonomous manner.

  18. EBF1 and FOXO1 act in a positive feedback circuitry to promote and stabilize specification to the B-cell lineage

  19. Lentiviral vector induced insertional haploinsufficiency of Ebf1 causes murine leukemia

  20. Data indicate binding of Runx1-Cbfbeta complexes to the Ebf1 proximal promoter in early B cell development.

Human Early B-Cell Factor 1 (EBF1) interaction partners

  1. Alleles rs115662534(T) and rs548231435(C), Disrupt the Binding of Transcription Factors STAT1 and EBF1 to the Regulatory Elements of Human CD40 Gene

  2. The results show that the mutation (CT+TT) at the rs987401919 and rs36071027 loci of EBF1 and its interaction with smoking and drinking are risk factors for coronary artery disease in Chinese patients.

  3. EBF1 acts as a pioneer transcription factor that operates in a transcription factor network to activate B cell-specific genes and repress genes associated with alternative cell fates. (Review)

  4. EBF1-PDGFRB is sufficient to drive leukemogenesis.

  5. EBF1 modifies the breast cancer subtype-specific methylation and gene expression program.

  6. EBF1 was down-regulated in cholangiocarcinoma (CCA) tissues and cell lines.

  7. Data show that GS Homeobox 2 (Gsx2) and Early B-cell factor 1 (Ebf1) combined overexpression in human embryonic stem (hES) cells achieves high yields of medium spiny neurons (MSNs).

  8. this study demonstrates a role for the AHR in regulating human B cell development, and it suggests that transcriptional alterations of EBF1 by the AHR are involved in the underlying mechanism

  9. In a Chinese population the TT genotype and T alleles in rs36071027 in the EBF1 gene are associated with an increased risk of coronary artery disease and its severity.

  10. A genome-wide significant association was observed for rs35715456 (log10BF = 6.3) on chromosome 18 for the dichotomous trait of having at least one long-lived parent versus not having any long-lived parent. The most significant association among single nucleotide polymorphisms in longevity candidate genes (APOE, MINIPP1, FOXO3, EBF1, CAMKIV, and OTOL1) was observed in the EBF1 gene region (rs17056207, p = .0002).

  11. In this genomewide association study, we found that variants at the EBF1, EEFSEC, AGTR2, WNT4, ADCY5, and RAP2C loci were associated with gestational duration and variants at the EBF1, EEFSEC, and AGTR2 loci with preterm birth.

  12. EBF1 polymorphism is associated with metabolic diseases.

  13. Among 15 childhood ALL patients with EBF1-PDGFRB fusion proteins, the fusion arose from interstitial deletion of 5q33 (n = 11), balanced rearrangement (n = 2), or complex rearrangement (n = 2).

  14. EBF1 is critical for transcriptional control of SLAMF1 gene in human B cells.

  15. The four single-nucleotide polymorphisms that had strong linkage disequilibrium relationships (rs10061900, rs10070743, rs4704967, and rs10056564) demonstrated significant interactions with the waist-hip ratio in the dominant model.

  16. two multi-zinc finger transcription cofactors named ZNF423 and ZNF521 have been characterised as potent inhibitors of EBF1 and are emerging as potentially relevant contributors to the development of B-cell leukaemias

  17. Studied whether EBF1 expression and biological activity in white adipose tissue is related to different metabolic parameters.

  18. role in the expression of Latent membrane protein 1

  19. early B cell factor-1 (EBF1) was identified as a co-regulator of gene expression with MEF2C.

  20. Epstein-Barr Virus EBNA1 bound to host genes of high significance for B-cell growth and function, including MEF2B, IL6R, and EBF1.

EBF1 Protein Profile

Protein Summary

Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.

Gene names and symbols associated with Early B-Cell Factor 1 Proteins (EBF1)

  • early B-cell factor 1 (EBF1)
  • early B cell factor 1 (Ebf1)
  • early B-cell factor 1 (Ebf1)
  • 9830166E18Rik protein
  • AW990631 protein
  • COE1 protein
  • EBF protein
  • EBF1 protein
  • O/E-1 protein
  • Olf-1 protein
  • OLF1 protein

Protein level used designations for Early B-Cell Factor 1 Proteins (EBF1)

early B-cell factor 1 , transcription factor COE1-like , OE-1 , transcription factor COE1 , Collier, Olf and EBF transcription factor 1 , olfactory neuronal transcription factor 1 , early B-cell factor (olfactory neuronal transcription factor 1) , o/E-1 , olf-1 , olfactory neuronal transcription factor , early B-cell factor 1 protein

462229 Pan troglodytes
100393955 Callithrix jacchus
100434003 Pongo abelii
100604994 Nomascus leucogenys
13591 Mus musculus
1879 Homo sapiens
116543 Rattus norvegicus
395512 Gallus gallus
479312 Canis lupus familiaris
537712 Bos taurus
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