anti-Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) Antibodies

The protein encoded by ENTPD2 is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Additionally we are shipping ENTPD2 Proteins (10) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ENTPD2 954 Q9Y5L3
ENTPD2 12496 O55026
ENTPD2 64467 O35795
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Top anti-ENTPD2 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ENTPD2 Antibody (N-term) (ABIN653273) in K562 cell line lysates (35 µg/lane). ENTPD2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with ENTPD2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow Cytometry analysis of ZR-75-1 cells using ENTPD2 / CD39L1 Antibody (N-term) Cat.-No AP51438PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human brain tissue reacted with ENTPD2 / CD39L1 Antibody (N-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-ENTPD2 antibody  ABIN1048566 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-ENTPD2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-ENTPD2 antibody  ABIN960774 IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-ENTPD2 antibody  ABIN960774 IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ENTPD2 using HuvEc whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF/ICC, WB Immunofluorescence analysis of A549 cells using ENTPD2 antibody (ABIN5973955). Blue: DAPI for nuclear staining. 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 12 to 14 Days
$686.14
Details
Human Rabbit Un-conjugated IF Immunofluorescence analysis of A549 cells using ENTPD2 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunofluorescence analysis of A549 cell using ENTPD2 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
$366.77
Details
Mouse Sheep Un-conjugated IP, ELISA, WB   100 μg Log in to see 11 to 14 Days
$1,145.83
Details

Top referenced anti-ENTPD2 Antibodies

  1. Human Polyclonal ENTPD2 Primary Antibody for IF (p), IHC (p) - ABIN1385820 : Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. in Toxicology and applied pharmacology 2016 (PubMed)

More Antibodies against ENTPD2 Interaction Partners

Human Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) interaction partners

  1. In oviducts, remarkably, ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase2), with the ability to hydrolyze ATP to AMP, are expressed in ciliated epithelial cells but with different subcellular localization.

  2. Hypoxia upregulates ENTPD2 through HIF-1alpha in hepatocellular carcinoma and subsequently leading to the accumulation of extracellular 5'-AMP, which maintains myeloid-derived suppressor cells undifferentiated.

  3. NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease.

  4. the lack of ecto-nucleotidase activity exhibited by NTPDase2 beta and -2 gamma and the C399S mutant, as well as the large reduction of activity in the N443D mutant are due to alterations in the folding/maturation of these proteins

  5. NTPDase2 preferentially hydrolyzes nucleoside triphosphates.

  6. down-regulation in biliary cirrhosis

  7. NTPDase2 has a role in portal fibroblast regulation of bile duct epithelium proliferation

  8. Mutagenesis study indicate the importance of K62 located in CR1, K182 downstream of ACR3, and R155. Mutation of Asp at the six potential glycosylation sites showed the importance of N64 in CR1 and N443 in ACR5 in protein function and expression

  9. The role of cysteine 26 in the catalytic activity of NTPDase-2 and as the target of p-chloromercuriphenylsulfonate (pCMPS), a sulfhydryl reagent and NTPDase-2 inhibitor, is reported.

Mouse (Murine) Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) interaction partners

  1. NTPDase2 protects from liver fibrosis but Entpd2 deletion does not significantly impact fibrosis

  2. NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease.

  3. Mesenteric endothelial cells are primed by schistosomiasis to a pro-inflammatory phenotype characterized by an increased expression of NTPDases 2 and 3, favoring ADP accumulation and mononuclear cell adhesion, possibly contributing to mesenteric inflammation and schistosomiasis morbidity via P2Y1 receptor signaling.

  4. The analysis of single and double KO mice demonstrated that NTPDase2 and P2Y1 receptors are not required for murine eye formation

  5. Authors propose that NTPDase2 has functionality in scavenging mitogenic extracellular nucleoside triphosphates in neurogenic niches of the adult brain, acting as a homeostatic regulator of nucleotide-mediated neural progenitor cell proliferation.

  6. Data indicate the absence of NTPDase2 and ATPase enzyme activity in taste buds of knockout mice, and suggest that NTPDase2 is the dominant form in taste buds.

  7. The medial habenula contains a specific perineuronal nonstellate subtype of astrocyte that expresses NTPDase2, strategically positioned to modulate purinergic transmission.

  8. catalytic properties and vascular topography have implications for thromboregulation

  9. NTPDases may modulate regulatory effects of ATP and degradation products within the vasculature and other sites and thereby potentially influence physiological as well as multiple pathological events in the kidney.

  10. Our results identify the ecto-nucleotidase NTPDase2 and functional P2X receptors at hippocampal progenitor cells

  11. In the mouse retina, NTPDase2 was chiefly localized in Muller glia and ganglion cell processes.

ENTPD2 Antigen Profile

Protein Summary

The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with ENTPD2

  • ectonucleoside triphosphate diphosphohydrolase 2 (entpd2) antibody
  • ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) antibody
  • Ectonucleoside triphosphate diphosphohydrolase 2 (enp2) antibody
  • ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2) antibody
  • Cd39l1 antibody
  • MGC76207 antibody
  • MGC151796 antibody
  • NTPDase-2 antibody
  • NTPDase2 antibody

Protein level used designations for ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2 , Ectonucleoside triphosphate diphosphohydrolase 2 , CD39 antigen-like 1 , NTPDase 2 , ecto-ATP diphosphohydrolase 2 , ecto-ATPDase 2 , ecto-ATPase 2 , testicular ecto-ATPase , cell membrane ecto-ATPase

GENE ID SPECIES
407961 Xenopus (Silurana) tropicalis
464883 Pan troglodytes
491241 Canis lupus familiaris
100196606 Salmo salar
100227326 Taeniopygia guttata
721617 Macaca mulatta
100126045 Bos taurus
100412544 Callithrix jacchus
954 Homo sapiens
12496 Mus musculus
64467 Rattus norvegicus
395797 Gallus gallus
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