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Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Additionally we are shipping ELP6 Proteins (8) and many more products for this protein.
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ELP6 is expressed intracellularly in developing and mature granulocytes and monocytes but not in lymphocytes and erythrocytes.
data identify DERP6/ELP5 and C3ORF75/ELP6 as key players for migration, invasion and tumorigenicity of melanoma cells, as integral subunits of Elongator.
a single point mutation in the gene encoding Elongator complex subunit 6 causing Purkinje neuron degeneration and an ataxia-like phenotype in the mutant wobbly mouse, is reported.
Arabidopsis Elongator post-transcriptionally modulates PIN protein levels.
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 (By similarity). Promotes organs development by modulating cell division rate. Involved in oxidative stress signaling. Prevents anthocyanins accumulation.
UPF0405 protein C3orf75
, angiotonin-transactivated protein 1
, elongator complex protein 6
, elongator complex protein 6 homolog
, transmembrane protein 103
, UPF0405 protein C3orf75 homolog