anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) Antibodies

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. Additionally we are shipping ERVW-1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERVW-1 30816 Q9UQF0
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Top anti-ERVW-1 Antibodies at

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ERVWE1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  MCF7 cell lysate 100 μL 2 to 3 Days
Human Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  ERVW-1  Sample Type:  HT1080 Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
Human Rabbit Un-conjugated WB 100 μg 4 to 6 Days
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated WB ERVWE1 Antibody (C-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ERVWE1 antibody detected the ERVWE1 protein (arrow). 400 μL 10 to 11 Days
Human Rabbit Un-conjugated WB ERVWE1 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
Human Rabbit APC ELISA, WB   200 μL 11 to 14 Days
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL 11 to 14 Days
Human Rabbit PE ELISA, WB   200 μL 11 to 14 Days
Human Rabbit Biotin ELISA, WB   200 μL 11 to 14 Days

Top referenced anti-ERVW-1 Antibodies

  1. Human Polyclonal ERVW-1 Primary Antibody for ELISA, WB - ABIN6923103 : Fischer, Weber, Kuhn, Fitzgerald, Schulze, Friese, Walzel, Markert, Jeschke: Is galectin-1 a trigger for trophoblast cell fusion?: the MAP-kinase pathway and syncytium formation in trophoblast tumour cells BeWo. in Molecular human reproduction 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ERVW-1 Interaction Partners

Human Endogenous Retrovirus Group W, Member 1 (ERVW-1) interaction partners

  1. These data revealed that human endogenous retrovirus W env might contribute to increase nitric oxide production and microglial migration ability in neuropsychological disorders by regulating the expression of inducible nitric oxide synthase.

  2. CD47 seems to mediate fusion mostly through broad contact surfaces between the partners' cell membrane while syncytin-1 mediate fusion through phagocytic-cup like structure.

  3. HERV-W was expressed in demyelinated lesions from multiple sclerosis brains, which were all positive for this endogenous pathogenic protein. Pronounced HERV-W immunoreactivity in active multiple sclerosis lesions was intimately associated with areas of active demyelination throughout the successive stages of lesion evolution in multiple sclerosis brains.

  4. ERVWE1, ERVFRDE1 and ERV3 transcription was down-regulated in hydatidiform moles and gestational trophoblastic neoplasia.

  5. Study found no associations between embroynal ERVW-1 polymorphisms and preeclampsia.

  6. Identification of the two CpG dinucleotides around transcription start site as key epigenetic elements has provided valuable information for further studies on the epigenetic regulation of syncytin-1 in pancreatic cancer cells

  7. Positive associations were observed between HERV-w methylation and dietary intakes of beta-carotene and carotenoids in a population of obese subjects.

  8. Syncytin-1 and ASCT-2 is localized at the acrosomal region and equatorial segment of the spermatozoa.

  9. Data show that Multiple Sclerosis-Associated Retrovirus (MSRV) is predominantly expressed over ERWVE1 in astrocyte-derived U-87 glioblastoma cell line.

  10. The effect of ETS1 on syncytialization of trophoblasts likely results, at least in part, from inhibition of syncytin expression.

  11. These results indicated that aberrant hypermethylation is involved in downregulation of syncytin-1, and epigenetic alterations may play a significant role in the development of preeclampsia

  12. Exosomes from cultured primary villous cytotrophoblasts and sera of pregnant women have syncytin-1 on their surfaces. It acts on cellular binding and uptake of exosomes.

  13. Increased trophoblast apoptosis and altered expression levels of syncytin-1, calpain 1, and AIF is observed in preeclamptic placentas.

  14. Syncytin-1 overexpression may be an indicator of urothelial cell carcinoma risk.

  15. Insertionally polymorphic HERV-K113 and HERV-K115 are not associated with HIV infections.

  16. Influenza A virus infection transactivated ERVWE1 by increasing the transcription of GCM1.

  17. Overexpression of HERV-W envelope gene elevated the levels of SK3 channel in neuroblastoma cells.

  18. Syncytin-1 knockdown significantly inhibited BeWo cell growth and DNA synthesis and Syncytin-1 could promote the G1/S transition through p15 and CDK4.

  19. In discordant monozygotic twins, HERVWE1 expression is higher in smaller fetuses and lower in larger counterparts. Methylation of the HERVWE1 gene promoter region may participate in gene regulation.

  20. This study linked decreased Syncytin-1 expression to an epigenetic hypermethylation of the entire promoter of ERVW-1.

ERVW-1 Antigen Profile

Protein Summary

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ERVW-1

  • endogenous retrovirus group W member 1, envelope (ERVW-1) antibody
  • ENV antibody
  • ENVW antibody
  • ERVWE1 antibody
  • HERV-7q antibody
  • HERV-W-ENV antibody
  • HERV7Q antibody
  • HERVW antibody
  • HERVWENV antibody

Protein level used designations for ERVW-1

HERV-7q envelope protein , HERV-W Env glycoprotein , HERV-W envelope protein , HERV-W_7q21.2 provirus ancestral Env polyprotein , HERV-W{7q21.1} provirus ancestral Env polyprotein , HERV-tryptophan envelope protein , endogenous retroviral family W, env(C7), member 1 , endogenous retrovirus group W member 1 , env-W , envelope glycoprotein , envelope polyprotein gPr73 , envelope protein , enverin , human endogenous retrovirus W envC7-1 envelope protein , syncytin A , syncytin-1

30816 Homo sapiens
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