Endothelin Converting Enzyme-Like 1 Proteins (ECEL1)

ECEL1 encodes a member of the M13 family of endopeptidases. Additionally we are shipping ECEL1 Antibodies (13) and ECEL1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ECEL1 9427 O95672
ECEL1 13599 Q9JMI0
ECEL1 60417 Q9JHL3
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Top ECEL1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 60 to 65 Days
$7,506.65
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Wheat germ Human GST tag 2 μg 11 to 12 Days
$338.33
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$2,053.33
Details

ECEL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,
Rat (Rattus)

More Proteins for Endothelin Converting Enzyme-Like 1 (ECEL1) Interaction Partners

Human Endothelin Converting Enzyme-Like 1 (ECEL1) interaction partners

  1. A novel ECEL1 homozygote mutation in the patient with distal arthrogryposis multiplex congenita type 5D to include pretibial vertical skin creases.

  2. Mutation of a conserved residue in ECEL1 is linked with fetal arthrogryposis multiplex congenita.

  3. Our clinical findings are consistent with recessive ECEL1 mutations causing variably penetrant orbital dysinnervation phenotypes (ptosis and/or complex strabismus with abnormal synkinesis)

  4. Three novel ECEL1 mutations have been identified in consanguineous pedigrees of Saudi Arabian origin presenting with distal arthrogryposis type 5D.

  5. A novel missense c.1819G>A mutation (G607S) in the ECEL1 gene has been identified in a consanguineous pedigree of Turkish origin presenting with congenital contracture syndromes.

  6. We described a new and homogenous phenotype of DA associated with ECEL1 that resulted in symptoms involving rather the peripheral than the central nervous system and suggesting a developmental dysfunction

  7. Mutations in ECEL1 cause distal arthrogryposis type 5D.

  8. Sp1 recruits ATF3, c-Jun, and STAT3 to obtain the requisite synergistic effect in neuronal injury through DINE neuronal injury-inducible gene

Mouse (Murine) Endothelin Converting Enzyme-Like 1 (ECEL1) interaction partners

  1. This study demonstrated that the ECEL1/DINE G607S and C760R mutations both lead to motor innervation defects as primary causes in ECEL1-mutated congenital contracture disorders.

  2. DINE is expressed in cranial and spinal motor neurons both embryonically and after CNS injury

  3. DINE enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury.

  4. Using two different DINE mutant mice, study found that DINE functional disruption leads to impaired axonal arborization of motor nerves in limb muscles.

  5. The data of this study suggested that DINE is a crucial molecule in distal axonal arborization into muscle to establish neuromuscular junctions.

  6. Sp1 recruits ATF3, c-Jun, and STAT3 to obtain the requisite synergistic effect in neuronal injury through DINE neuronal injury-inducible gene

ECEL1 Protein Profile

Protein Summary

This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

Gene names and symbols associated with ECEL1

  • endothelin converting enzyme like 1 (ECEL1)
  • endothelin converting enzyme-like 1 L homeolog (ecel1.L)
  • endothelin-converting enzyme-like 1 (LOC721061)
  • endothelin-converting enzyme-like 1 (LOC100399806)
  • endothelin-converting enzyme-like 1 (LOC100438216)
  • endothelin converting enzyme-like 1 (Ecel1)
  • DA5D protein
  • Dine protein
  • ECEL1 protein
  • ECEX protein
  • xce protein

Protein level used designations for ECEL1

endothelin converting enzyme-like 1 , endothelin-converting enzyme-like 1-like , X converting enzyme , damage induced neuronal endopeptidase , endothelin-converting enzyme-like 1 , damage-induced neuronal endopeptidase , metallopeptidase , xce protein

GENE ID SPECIES
460013 Pan troglodytes
486161 Canis lupus familiaris
495020 Xenopus laevis
721061 Macaca mulatta
100352359 Oryctolagus cuniculus
100399806 Callithrix jacchus
100438216 Pongo abelii
100592362 Nomascus leucogenys
9427 Homo sapiens
13599 Mus musculus
60417 Rattus norvegicus
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