Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) ELISA Kits

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009].. Additionally we are shipping EZH1 Antibodies (126) and EZH1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EZH1 2145 Q92800
EZH1 14055 P70351
Anti-Rat EZH1 EZH1 303547  
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Top EZH1 ELISA Kits at antibodies-online.com

Showing 4 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.113 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$736.84
Details
Mouse 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$757.89
Details
Human < 0.113 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$902.56
Details
Mouse < 0.061 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$902.56
Details

More ELISA Kits for EZH1 Interaction Partners

Human Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) interaction partners

  1. EZH1 mutations predominantly occurred in clinically benign follicular neoplasms without RAS mutations.

  2. functions mostly within canonical PRC2 and exhibits proliferation-dependent redundancy that shapes mutational signatures in cancer

  3. Overexpression the EZH1 gene inhibited HK-2 cell apoptosis, reduced ROS levels, and down-regulated the expressions of IL-1beta, IL-6, TNF-alpha, Bax and Cyt C mRNA and protein, and increased the expressions of Bcl-2 and NFKBIA, CXCL8 and cyclin D1, indicating that overexpression of EZH1 suppressed NF-kappaB signaling in aristolochic acid-injured HK-2 cells.

  4. identification of EZH1 as a repressor of haematopoietic multipotency in the early mammalian embryo

  5. pVHL loss causes the transcriptional activation of hypoxia-inducible factor (HIF) target genes, including many genes that encode histone lysine demethylases.

  6. Data show that embryonic stem cells with deletion of EZH1 or EZH2 fail to differentiate into ectoderm lineages.

  7. Expression of the EZH2 homolog EZH1 is reduced in EZH2-deficient CML LICs, creating a scenario resembling complete loss of PRC2. EZH2 dependence of CML LICs raises prospects for improved therapy of TKI-resistant CML and/or eradication of disease by addition of EZH2 inhibitors

  8. a hot-spot mutation in EZH1 is the second most frequent genetic alteration in autonomous thyroid adenomas; the association between EZH1 and TSHR mutations suggests a 2-hit model for the pathogenesis of these tumors, whereby constitutive activation of the cAMP pathway and EZH1 mutations cooperate to induce the hyperproliferation of thyroid cells

  9. EZH1, SUZ12 and UXT work synergistically to regulate pathway activation in the nucleus.

  10. The authors report a novel PRC2-Ezh1 function that utilizes Ezh1beta as an adaptive stress sensor in the cytoplasm, thus allowing postmitotic cells to maintain tissue integrity in response to environmental changes.

  11. These evidences suggest that EZH2 and EZH1 are important in the counter-balancing mechanisms controlling proliferation/resting of lymphoid cells. The disruption of the balanced EZH2/EZH1 ratio may play important roles in the pathogenesis of lymphomas

  12. The related enzymatic subunits EZH1 and EZH2 undergo an expression switch during blood cell development.

  13. EZH1 maintains repressive chromatin through different mechanisms.

Mouse (Murine) Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) interaction partners

  1. Depletion of EZH1 in the prefrontal cortex attenuated sociability, enhanced motivational behaviors and affected gene expression pathways.

  2. The Polycomb repressive complex 2 proteins EZH1 and EZH2 regulate genes that control hepatocyte maturation and fibrogenesis and genes not specifically associated with the liver lineage by acting at euchromatic promoter regions. EZH1 and EZH2 thereby promote liver homeostasis and prevent liver damage.

  3. The combined loss of Ezh1 and Ezh2 in chondrocytes severely impairs skeletal growth in mice.

  4. identification of EZH1 as a repressor of haematopoietic multipotency in the early mammalian embryo

  5. Suggest that EZH1 and -2 are novel targets of miR-214-3p, and miR-214-3p might be one potential miRNA for the prevention of cardiac fibrosis.

  6. Ezh1 is required for neonatal heart regeneration and development.

  7. in the skin epithelium, EED, Suz12, and Ezh1/2 function largely as subunits of the PRC2 complex and have roles in skin development

  8. the expression level of Ezh1 determines the restoration of H3K27 methylation in the absence of the canonical EZH2-PRC2.

  9. These results clearly demonstrated an essential role of Ezh1 in the pathogenesis of hematopoietic malignancies induced by Ezh2 insufficiency, and highlighted the differential functions of Ezh1 and Ezh2 in hematopoiesis.

  10. Loss of EZH1 is associated with increased liver injury and a blunted regenerative response.

  11. Data show that histone lysine methyltransferase Ezh1 promotes toll-like receptor (TLR)-triggered inflammatory cytokine production by suppressing the Toll-interacting protein (Tollip), contributing to full activation of the innate immunity.

  12. presence of Ezh1 helps to maintain PRC2 occupancy on its target genes in myoblasts where Jarid2 is not expressed.

  13. Deletion of Ezh1 and Ezh2 from skin results in a marked change in fate determination in epidermal progenitor cells, leading to an increase in the number of lineage-committed Merkel cells, specialized subtype of skin cells involved in mechanotransduction.

  14. Ezh1 is an important histone methyltransferase for hematopietic stem cell maintenance.

  15. Ezh1 has a role in promoting mRNA transcription.

  16. while Ezh1/2-null hair follicles (HFs) arrest morphogenesis and degenerate due to defective proliferation and increased apoptosis, epidermis hyperproliferates and survives engraftment

EZH1 Antigen Profile

Antigen Summary

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008

Gene names and symbols associated with EZH1

  • enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) antibody
  • enhancer of zeste 1 polycomb repressive complex 2 subunit (ezh1) antibody
  • enhancer of zeste 1 polycomb repressive complex 2 subunit (Ezh1) antibody
  • AW557915 antibody
  • EZH1 antibody
  • KMT6B antibody
  • mKIAA0388 antibody
  • si:ch211-250i3.1 antibody
  • zgc:136829 antibody

Protein level used designations for EZH1

ENX-2 , histone-lysine N-methyltransferase EZH1 , enhancer of zeste 1 , enhancer of zeste homolog 1 (Drosophila) , enhancer of zeste homolog 1-like , histone-lysine N-methyltransferase EZH1-like , enhancer of zeste homolog 1

GENE ID SPECIES
2145 Homo sapiens
664754 Danio rerio
14055 Mus musculus
303547 Rattus norvegicus
420023 Gallus gallus
454697 Pan troglodytes
480516 Canis lupus familiaris
533087 Bos taurus
100052411 Equus caballus
100351852 Oryctolagus cuniculus
100411881 Callithrix jacchus
100547448 Meleagris gallopavo
100559669 Anolis carolinensis
100604860 Nomascus leucogenys
100518394 Sus scrofa
100720693 Cavia porcellus
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