anti-Epoxide Hydrolase 2, Cytoplasmic (EPHX2) Antibodies

EPHX2 encodes a member of the epoxide hydrolase family. Additionally we are shipping Epoxide Hydrolase 2, Cytoplasmic Proteins (7) and Epoxide Hydrolase 2, Cytoplasmic Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EPHX2 2053 P34913
EPHX2 13850 P34914
EPHX2 65030 P80299
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Top anti-Epoxide Hydrolase 2, Cytoplasmic Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of EPHX2 expression in rat lung extract ( Lane 1), mouse lung extract ( Lane 2) and HEPG2 whole cell lysates ( Lane 3). EPHX2 at 62KD was detected using rabbit anti- EPHX2 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$522.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: EPHX2 Antibody [NBP2-44321] - Analysis of of Human Kidney lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-EPHX2 antibody  ABIN1048574 IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-EPHX2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat kidney using EPHX2 antibody at dilution of 1:200 (x40 lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Kidney (formalin-fixed, paraffin-embedded) stained with EPHX2 antibody ABIN290080 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-EPHX2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) Heart, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details

EPHX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-Epoxide Hydrolase 2, Cytoplasmic Antibodies

  1. Human Polyclonal EPHX2 Primary Antibody for ELISA, WB - ABIN4308763 : Nelson, Subrahmanyan, Summers, Xiao, Alkayed: Soluble epoxide hydrolase dimerization is required for hydrolase activity. in The Journal of biological chemistry 2013 (PubMed)

More Antibodies against Epoxide Hydrolase 2, Cytoplasmic Interaction Partners

Human Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. Single nucleotide polymorphism of EPHX2 rs751141 is associated with Early Neurological Deterioration.

  2. The activity of Ephx2 prom (show ESR1 Antibodies)oter-coding luciferase was significantly attenuated in HEK293T cells treated with 17beta-E2.

  3. hypomethylation of the promoter region of EPHX2 and K55R polymorphism were associated with significant increased risk of pre-eclampsia.

  4. Study demonstrated an isolated gene change, sEH R287Q, in a core family of familial hypercholesterolemia (FH). The results showed that sEH R287Q decreased the expression level and hydrolase activity of sEH, decreased the binding of LDL to LDLR (show LDLR Antibodies) and LDL internalization in cultured hepatocyte cell line BEL (show LHX2 Antibodies)-7402.

  5. Soluble epoxide hydrolase plays role in the choroidal neovascularization

  6. Interestingly, rs2279590 locus has a widespread enhancer effect on two nearby genes, protein tyrosine kinase 2 beta (PTK2B (show PTK2B Antibodies)) and epoxide hydrolase-2 (EPHX2); both of which have been previously associated with AD as risk factors.

  7. Results showed that among type 2 diabetic patients, the combined effect of MTHFR (show MTHFR Antibodies) TT and EPHX2 GG or GA + AA genotype has a higher risk of ischemic stroke compared with the control group.

  8. we describe the bacterial expression of the recombinant N-terminal domain of sEH-P and the development of a high-throughput screening protocol using a sensitive and commercially available substrate fluorescein diphosphate. The usability of the assay system was demonstrated and novel inhibitors of sEH-P were identified.

  9. The WT sEH formed a very tight dimer, with a KD/M in the low picomolar range. Only R287Q resulted in a large change of the KD/M However, human tissue concentrations of sEH suggest that it is always in its dimer form independently of the SNP.

  10. The EPHX2 Lys55Arg polymorphism is associated with AKI following cardiac surgery in patients without preexisting CKD

Mouse (Murine) Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. Estrogen/estrogen receptor (show ESR1 Antibodies)-dependent methylation of the promoter region silences Ephx2 expression.

  2. Data (including data from studies in knockout mice) suggest that expression of Ephx2 measured as mRNA, protein, and enzymatic activity is markedly up-regulated in corneal epithelium and retina in type 1 and type 2 diabetes; induction of Ephx2 may play roles in diabetic cataracts, diabetic retinopathy, and delayed wound healing.

  3. These findings establish sEH in podocytes as a significant contributor to renal function under hyperglycemia. These data suggest that sEH is a potential therapeutic target for podocytopathies

  4. Findings identify soluble epoxide hydrolase (sEH) in podocytes as a contributor to signaling events in acute renal injury and suggest that sEH inhibition may be of therapeutic value in proteinuria.

  5. These data demonstrate that genetic deletion of sEH resulted in an altered oxylipin profile, which may have led to an enhanced CRH (show CRH Antibodies) response.

  6. Deficiency or pharmacological inhibition of sEH protected mice from the lipopolysaccharide-induced decrease in systemic arterial oxygen concentration.

  7. Lungs of Ephx2(-/-) mice had a less pronounced inflammatory response and less autophagy with mild distal airspace enlargement accompanied by restored lung function and steady weight gain

  8. over-expression of sEH enhances A1AR (show ADORA1 Antibodies)-dependent contraction and reduces KATP channel-dependent relaxation in MAs (show MAS1 Antibodies). These results suggest a possible interaction between sEH, A1AR (show ADORA1 Antibodies), and KATP channels in regulating vascular tone.

  9. we identified 31 significantly expressed proteins in mouse hippocampus using proteomics analysis and constructed a protein-protein interaction network associated with EPHX2 gene knockout

  10. The role of soluble epoxide hydrolase in the pathophysiology of depression and resilience to repeated social defeat stress

Cow (Bovine) Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. AP-1 (show JUN Antibodies) activation is involved in the transcriptional up-regulation of sEH by angiotensin II (Ang II) in endothelial cells, which may contribute to Ang II (show AGT Antibodies)-induced hypertension[soluble epoxide hydrolase ]

Epoxide Hydrolase 2, Cytoplasmic (EPHX2) Antigen Profile

Protein Summary

This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with EPHX2

  • epoxide hydrolase 2 (EPHX2) antibody
  • soluble epoxide hydrolase (SEH2) antibody
  • soluble epoxide hydrolase (PTRG_01276) antibody
  • Soluble epoxide hydrolase (Deima_0402) antibody
  • Soluble epoxide hydrolase (Deipr_0144) antibody
  • Soluble epoxide hydrolase (Psed_0418) antibody
  • Soluble epoxide hydrolase (Fluta_3767) antibody
  • alpha/beta hydrolase (HALXA_RS12710) antibody
  • epoxide hydrolase 2, cytoplasmic (Ephx2) antibody
  • epoxide hydrolase 2 (Ephx2) antibody
  • CEH antibody
  • Eph2 antibody
  • SEH antibody
  • sEP antibody

Protein level used designations for EPHX2

epoxide hydrolase 2 , soluble epoxide hydrolase , Soluble epoxide hydrolase , bifunctional epoxide hydrolase 2 , epoxide hydratase , epoxide hydrolase 2, cytosolic , epoxide hydrolase, soluble , cytosolic epoxide hydrolase , epoxide hydrolase 2C , CEH , SEH

GENE ID SPECIES
421999 Gallus gallus
4836743 Scheffersomyces stipitis CBS 6054
6339307 Pyrenophora tritici-repentis Pt-1C-BFP
10149715 Deinococcus maricopensis DSM 21211
10255604 Deinococcus proteolyticus MRP
10362229 Pseudonocardia dioxanivorans CB1190
10399141 Fluviicola taffensis DSM 16823
10798230 Halopiger xanaduensis SH-6
2053 Homo sapiens
13850 Mus musculus
65030 Rattus norvegicus
477373 Canis lupus familiaris
414425 Sus scrofa
511716 Bos taurus
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