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Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. Additionally we are shipping Ermin, ERM-Like Protein Kits (10) and Ermin, ERM-Like Protein Proteins (7) and many more products for this protein.
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Human Polyclonal ERMN Primary Antibody for IHC, IHC (p) - ABIN4309479
Fagerberg, Oksvold, Skogs, Algenäs, Lundberg, Pontén, Sivertsson, Odeberg, Klevebring, Kampf, Asplund, Sjöstedt, Al-Khalili Szigyarto, Edqvist, Olsson, Rydberg, Hudson, Ottosson Takanen, Berling et al.: Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP). ... in Journal of proteome research 2013
this study suggested a role for hErmin as a novel cytoskeleton-related oligodendroglial protein in human brain myelination and human epileptogenesis, and provide new evidence for the relationship between oligodendrocytes and epilepsy.
Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.
This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia.
plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity).