anti-Ets Variant 1 (ETV1) Antibodies

ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors. Additionally we are shipping ETV1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ETV1 2115 P50549
ETV1 362733  
ETV1 14009 P41164
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Top anti-ETV1 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ETV1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  HT1080 cell lysate Immunohistochemistry with Brain, cortex tissue at an antibody concentration of 5µg/ml using anti-ETV1 antibody (ARP38528_P050) 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ETV1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, treated with PMA 125ng/ml 30', using ER81 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Cow Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of ETV1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of ETV1 expression in mouse brain (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using ETV1 mouse mAb against truncated Trx-ETV1 recombinant protein (1) and full-length ETV1 (aa1-477)-hIgGFc transfected CHO-K1 cell lysate(2). Dilution: 1/500 - 1/2000 Figure 2: Western blot analysis using ETV1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV1 cDNA (2). Dilution: 1/500 - 1/2000 100 μL Log in to see 10 to 11 Days
$491.79
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using ER81 Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Anti-ETV1 / ER81 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958977 concentration 5 ug/ml. Anti-ETV1 / ER81 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this p ... 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274270 staining HuvEc cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from HUVEC cells treated with PMA using ER81 antibody.The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-ETV1 Antibodies

  1. Bat Polyclonal ETV1 Primary Antibody for WB - ABIN610584 : Feng, Tintrup, Kirsch, Nichol, Kuhse, Betz, Sanes: Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal ETV1 Primary Antibody for ELISA, WB - ABIN969120 : Cerveira, Ribeiro, Peixoto, Costa, Henrique, Jerónimo, Teixeira: TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions. in Neoplasia (New York, N.Y.) 2006 (PubMed)

  3. Dog (Canine) Polyclonal ETV1 Primary Antibody for ELISA - ABIN451677 : Tomlins, Rhodes, Perner, Dhanasekaran, Mehra, Sun, Varambally, Cao, Tchinda, Kuefer, Lee, Montie, Shah, Pienta, Rubin, Chinnaiyan: Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against ETV1 Interaction Partners

Human Ets Variant 1 (ETV1) interaction partners

  1. Our data indicate that miR-17-5p acts as a tumour suppressor in Triple-negative breast cancer (TNBC)by targeting ETV1, and a low-abundance of miR-17-5p may be involved in the pathogenesis of TNBC. These findings indicate that miR-17-5p may be a therapeutic target for TNBC

  2. four oncogenic ETS (ERG, ETV1, ETV4, and ETV5), and no other ETS, interact with the Ewing's sarcoma breakpoint protein, EWS.

  3. Our results indicate that assessing AP1 and PEA3 transcription factor status might be a good indicator of OAC status. However, we could not detect any associations with disease stage or patient treatment regime. This suggests that the PEA3-AP1 regulatory module more likely contributes more generally to the cancer phenotype. In keeping with this observation, depletion of ETV1 and/or ETV4 causes an OAC cell growth defect

  4. Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETV1, ETV4 and ETV5.

  5. the prostate cancer-related oncogenic E26 transformation-specific (ETS) transcription factors, ETV1, ETV4, and ETV5, were required for TAZ gene transcription in PC3 prostate cancer cells

  6. C646 treatment attenuated ETV1 protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 may serve as novel antineoplastic targets and that use of the selective HAT inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.

  7. these data reveal a JMJD2A/ETV1/YAP1 axis that promotes prostate cancer initiation and that may be a suitable target for therapeutic inhibition.

  8. conclude that ETV1 is specifically expressed in the majority of gastrointestinal stromal tumors, even in some KIT-negative cases

  9. ETV1 and COP1 are a pair of independent predictors of prognosis for triple-negative breast cancer.

  10. ETV1 overexpression is associated with prostate cancer aggressiveness.

  11. Results show that ETV1 was upregulated at a higher rate in Gastrointestinal stromal tumor and was correlated with KIT expression.

  12. These results illuminate the complex interplay of AR, ETV1, and PTEN pathways in pre-cancerous neoplasia and early tumorigenesis

  13. YK-4-279 is a potent inhibitor of ETV1 and inhibits both the primary tumor growth and metastasis of fusion positive prostate cancer xenografts.

  14. mutation of the KIT protein that stabilizes ETV1 is likely to be a key step by which an endogenous brain-cell progenitor may form a germinoma.

  15. ETV1 expression is a rare event in human melanoma and seems to be rather based on hyperactivation of MAPK signals, by BRAF (V600E) mutation, than on ETV1 gene amplification.

  16. developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1, ETV4, and ETV5 in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa specimens using RNA probes

  17. Elevated levels of either wild-type ETV1 or its truncated derivative, dETV1, which mimics the product of an oncogenic rearrangement in certain tumors, results in increased expression of mRNA for p14ARF, a known activator of p53.

  18. These results point to a new avenue for pharmacologic ETV1 inhibition and may inform a general means to discover small molecule perturbagens of transcription factor oncoproteins.

  19. The gastrointestinal stromal tumor-specific transcription factor ETV1 may have no prognostic potential, whereas its downstream gene KCTD10 is associated with a favorable prognosis.

  20. ETV1 expression is significantly correlated with Snail expression in human gastric tumor samples. In summary, we present data that ETV1 promotes Snail expression to induce EMT-like metastatic progression in gastric cancer.

Xenopus laevis Ets Variant 1 (ETV1) interaction partners

  1. we conclude that Etv1 acts downstream of FGF signaling to regulate the initiation of neurogenesis in the Xenopus retina.

Mouse (Murine) Ets Variant 1 (ETV1) interaction partners

  1. Here, we present a model in which the ETV1 promoter is used to specifically and inducibly drive Cre recombinase in ICC as a strategy to study GIST pathogenesis.

  2. Loss of Etv1 resulted in a complete disruption of the normal sodium current heterogeneity that exists between atrial, VCS, and ventricular myocytes.

  3. we described a RET-ER81-Neuregulin1 signaling pathway in neurons innervating Pacinian corpuscle somatosensory end organs, which is essential for communication between the innervating axon and the end organ

  4. Thus, taken into consideration the mechanism that controls the upregulation of maturation genes involved in synaptic formation, these results indicate that Etv1 orchestrates the activity-dependent regulation of both maturation and immaturation genes in developing granule cells and plays a key role in specifying the identity of mature granule cells in the cerebellum.

  5. downstream ETV1/4/5 transcriptional up-regulation appears highly sensitive and specific and can be used as a reliable molecular signature and diagnostic method for CIC fusion positive SBRCTs

  6. these data reveal a JMJD2A/ETV1/YAP1 axis that promotes prostate cancer initiation and that may be a suitable target for therapeutic inhibition.

  7. this study shows that network activity dynamically modulates the properties of fast-spiking (FS) interneurons through the postmitotic expression of the transcriptional regulator Er81.

  8. Data showed that ETV1 knockdown reduced KIT expression and GIST proliferation.

  9. both Etv1 and Ewsr1 were necessary for Fgf10 expression and elongation of the limb bud.

  10. ETV1 appeared to support development of invasive adenocarcinoma under the background of full Pten loss

  11. Study shows that the NR2C and Tiam1 maturation genes are synergistically controlled by the activity-dependent induction of Etv1.

  12. The coordinate expression of Etv1 with POMC cell differentiation and its interaction with the highly cell-restricted Tpit factor indicate that Etv1 participates in a combinatorial code for pituitary cell-specific gene expression.

  13. Etv1 orchestrates the activity-dependent gene regulation in the terminal maturation program and specifies the identity of cerebellar granule cells.

  14. ER81 is not necessary for expression of the OB dopaminergic gene cassette and that the DA-motif is not involved in differentiation of the mammalian OB dopaminergic phenotype.

  15. Studies indicate that Etv1 not only mediates specification of dopaminergic identity, but is also required for the proliferation and maintenance of bulbar dopaminergic neurons.

  16. Formation of supernumerary muscle spindles at the expense of Golgi tendon organs in ER81-deficient mice

  17. Few if any DRG neurons from Bax(-/-)/NT3(-/-) mice expressed ER81 protein. Expression of a NT3 transgene in muscle restored DRG ER81 expression.

  18. ER81 is a transcription factor in the ets family, within which it forms the PEA3 group.

  19. A neuron class defined by a molecular criterion doesn't segregate with that defined by an anatomical criterion; ER81 is involved in cell differentiation of a subset of layer 5 projection neurons, and this mechanism is conserved among rodents and primates.

  20. Etv1 is required for Pacinian corpuscle development.

Zebrafish Ets Variant 1 (ETV1) interaction partners

  1. er81 embryonic expression regulation does not require FGF signalling.

ETV1 Antigen Profile

Protein Summary

This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA

Gene names and symbols associated with anti-Ets Variant 1 (ETV1) Antibodies

  • ETS variant 1 (etv1) antibody
  • ETS variant 1 (ETV1) antibody
  • ets variant 1 (Etv1) antibody
  • ETS variant 1 S homeolog (etv1.S) antibody
  • ets variant 1 (etv1) antibody
  • ER81 antibody
  • Etsrp81 antibody
  • MGC75591 antibody
  • XER81 antibody

Protein level used designations for anti-Ets Variant 1 (ETV1) Antibodies

ets variant 1 , ets domain protein , ets variant gene 1 , ETS translocation variant 1 , ets-related protein 81 , ets-related transcription factor XER81 , ets related protein 81 , ETS transcription factor Er81 , er81

GENE ID SPECIES
394827 Xenopus (Silurana) tropicalis
463270 Pan troglodytes
100173436 Pongo abelii
100555473 Anolis carolinensis
100594736 Nomascus leucogenys
2115 Homo sapiens
475246 Canis lupus familiaris
362733 Rattus norvegicus
398358 Xenopus laevis
395748 Gallus gallus
540846 Bos taurus
14009 Mus musculus
563876 Danio rerio
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