anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibodies

The protein encoded by EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. Additionally we are shipping EHMT1 Proteins (4) and EHMT1 Kits (2) and many more products for this protein.

Gene Name	GeneID	UniProt
EHMT1	77683	Q5DW34
EHMT1	79813	Q9H9B1
EHMT1	362078

How to order from antibodies-online

+1 877 302 8632
+1 888 205 9894 (toll-free)
Order online
orders@antibodies-online.com

Top anti-EHMT1 Antibodies at antibodies-online.com

Showing 10 out of 135 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN387855	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN387856	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN387854	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN2486992	Human	Rabbit	Un-conjugated	ELISA, WB	50 μL	Log in to see	2 to 3 Days	$185.00	Details
ABIN387925	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN387926	Human	Rabbit	Un-conjugated	WB	400 μL	Log in to see	10 to 11 Days	$324.50	Details
ABIN5611009	Human	Rabbit	Un-conjugated	EIA, WB	0.1 mg	Log in to see	10 to 12 Days	$411.13	Details
ABIN5611011	Human	Rabbit	Un-conjugated	EIA, WB	0.1 mg	Log in to see	12 to 15 Days	$411.13	Details
ABIN5611010	Human	Rabbit	Un-conjugated	EIA, WB	0.1 mg	Log in to see	12 to 15 Days	$411.13	Details
ABIN356609	Human	Rabbit	Un-conjugated	EIA, WB	0.4 mL	Log in to see	6 to 8 Days	$390.50	Details

EHMT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes	Applications	Host	Clonality	Conjugate
Mouse (Murine)	,	,	,	, , , , , , , , ,
Human	, , , ,	, ,	,	, , , , , , , , , , , , ,
Rat (Rattus)		,	,

More product categories related to EHMT1 Antibody

More Antibodies against EHMT1 Interaction Partners

Mouse (Murine) Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

GLP (show GOLGA6A Antibodies)/G9a (show EHMT2 Antibodies) H3K9 methyltransferase complex is an enzyme counteracting Jmjd1a (show KDM3A Antibodies)-mediated H3K9 demethylation at the Sry (show SRY Antibodies) locus in gonadal somatic cells
miR (show MLXIP Antibodies)-217-mediated, genetic, or pharmacological inactivation of EHMT1/2 was sufficient to promote pathological hypertrophy
EHMT1 Mediates Homeostatic Synaptic Scaling
The stress-induced Brg1 (show SMARCA4 Antibodies)-G9a (show EHMT2 Antibodies)/GLP (show GOLGA6A Antibodies)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Antibodies) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.
data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 Antibodies) are epigenetic regulators involved in gamma-globin repression and represent a novel therapeutic target for SCD (show SCD Antibodies).
histone methyltransferase activities of GLP (show GOLGA6A Antibodies) and G9a (show EHMT2 Antibodies) are stimulated by neighboring nucleosomes that are premethylated at H3K9
Prdm16 (show PRDM16 Antibodies) was required in young mice to suppress the expression of white-fat-selective genes in BAT (show BAAT Antibodies) through recruitment of the histone methyltransferase Ehmt1.
G9a (show EHMT2 Antibodies) and GLP (show GOLGA6A Antibodies) have an essential role in normal morphogenesis of the atrioventricular septum through regulation of the size of the atrioventricular cushion.
Reduced Euchromatin histone methyltransferase 1 (show DNMT1 Antibodies) causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice.
EHMT1 is an essential BAT (show BAAT Antibodies)-enriched lysine methyltransferase in the PRDM16 (show PRDM16 Antibodies) transcriptional complex and controls brown adipose cell fate

Human Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

These results suggest that EHMT2 (show EHMT2 Antibodies) downregulation in CD4 (show CD4 Antibodies)(+) T-cells may be linked to a protection mechanism against the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM (show ATF7IP Antibodies)/TSP (show THBS1 Antibodies)).
Regulated methylation and phosphorylation serve as a switch controlling G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies) coactivator function, suggesting that this mechanism may be a general paradigm for directing specific transcription factor and coregulator actions on different genes.
trr (show TXNRD1 Antibodies) and G9a (show EHMT2 Antibodies) also have common direct targets, including the Drosophila ortholog of Arc (show NOL3 Antibodies) (Arc1 (show CDH1 Antibodies)), a key regulator of synaptic plasticity. Our data highlight the clinical and molecular convergence between the KMT2 and EHMT protein families, which may contribute to a molecular network underlying a larger group of intellectual disability / autism spectrum disorder -related disorders.
missense variants in EHMT1 that lead to protein misfolding and disrupted histone mark binding can lead to Kleefstra Syndrome [case reports]
we find an estrogen receptor (show ESR1 Antibodies)-independent synthetic lethal interaction between a GATA3 (show GATA3 Antibodies) frameshift mutant with an extended C-terminus and the histone methyltransferases G9A (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies), indicating perturbed epigenetic regulation
Selective degradation of the mutant EHMT1 mRNA leads to Kleefstra syndrome.
G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies) are required for stable maintenance of imprinted DNA methylation (show HELLS Antibodies) in embryonic stem cells.
the clinical picture we found in Norwegian patients with Kleefstra syndrome is similar to the findings described in the literature. An interesting point is that in the literature >85% of the patients have a deletion of 9q34.3 and the remaining have a mutation in the EHMT1 gene, whereas in this study we found 50% with a deletion, and 50% with a mutation.
Data indicate zinc finger proteins ZNF644 (show ZNF644 Antibodies) and WIZ (show ZNF803 Antibodies) as two core subunits in the histone-lysine N-methyltransferase G9a (show EHMT2 Antibodies)/GLP (show RCBTB1 Antibodies) complex, and interact with the transcription activation domain of G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies).
data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 Antibodies) are epigenetic regulators involved in gamma-globin (show HBG1 Antibodies) repression and represent a novel therapeutic target for SCD (show SCD Antibodies).

EHMT1 Antigen Profile

Protein Summary

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EHMT1

euchromatic histone lysine methyltransferase 1 (EHMT1) antibody
histone-lysine N-methyltransferase EHMT2 (LOC100121084) antibody
euchromatic histone-lysine N-methyltransferase 1 (ehmt1) antibody
euchromatic histone lysine methyltransferase 1 (ehmt1) antibody
euchromatic histone methyltransferase 1 (Ehmt1) antibody
euchromatic histone lysine methyltransferase 1 (Ehmt1) antibody

9230102N17Rik antibody
bA188C12.1 antibody
D330003E03 antibody
EHMT1 antibody
Eu-HMTase1 antibody
EUHMTASE1 antibody
FP13812 antibody
G9a antibody
GLP antibody
GLP1 antibody
KMT1D antibody
mKIAA1876 antibody

Protein level used designations for EHMT1

euchromatic histone methyltransferase 1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5 , euchromatic histone-lysine N-methyltransferase 1 , histone-lysine N-methyltransferase EHMT1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5-like , G9a-like protein 1 , lysine N-methyltransferase 1D , G9a like protein , H3-K9-HMTase 5 , histone H3-K9 methyltransferase 5

GENE ID	SPECIES
417250	Gallus gallus
464891	Pan troglodytes
491224	Canis lupus familiaris
528606	Bos taurus
100023838	Monodelphis domestica
100058869	Equus caballus
100078328	Ornithorhynchus anatinus
100121084	Nasonia vitripennis
100124713	Xenopus (Silurana) tropicalis
100217666	Taeniopygia guttata
100466861	Ailuropoda melanoleuca
100538392	Meleagris gallopavo
100565730	Anolis carolinensis
77683	Mus musculus
79813	Homo sapiens
362078	Rattus norvegicus

Selected quality suppliers for anti-EHMT1 (EHMT1) Antibodies

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com