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Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping F-Box Protein 28 Antibodies (37) and F-Box Protein 28 Proteins (6) and many more products for this protein.
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It was shown on human primary islets that FBXO28 improves pancreatic beta-cell survival under diabetogenic conditions without affecting insulin (show INS ELISA Kits) secretion.
Expression levels of TP53BP2 (show TP53BP2 ELISA Kits), FBXO28, and FAM53A genes were associated with patient survival specifically in ER-positive, TP53 (show TP53 ELISA Kits)-mutated tumors.
Fbxo28 regulates topoisomerase IIalpha decatenation activity and plays an important role in maintaining genomic stability.
Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures.
Study identified F-box protein (show FBXW10 ELISA Kits), FBXO28 that controls MYC (show MYC ELISA Kits)-dependent transcription by non-proteolytic ubiquitylation. Depletion of FBXO28 or overexpression of an F-box mutant unable to support MYC (show MYC ELISA Kits) ubiquitylation results in an impairment of MYC (show MYC ELISA Kits)-driven transcription, transformation and tumourigenesis.
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein 28
, F-box only protein 28
, centromere protein 30