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FBXO6 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 6 Antibodies (41) and F-Box Protein 6 Proteins (9) and many more products for this protein.
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Fbxo6 is a novel regulator of mitosis by controlling chromosome separation via interacting with the spindle checkpoint proteins Mad2 and BubR1.
FBXO6 as a functional E3 ubiquitin ligase for Ero1L that plays a critical role in inhibiting endoplasmic reticulum stress-induced apoptosis.
It might inhibit cadmium-induced ER stress by functioning as a ubiquitin ligase in the ERAD system, thereby attenuating the cell death induced by subsequent JNK1 activation.
systematical identification of the FBXO6-interacting glycoproteins, critical for clarifying its substrates as well as biological functions.
Two interacting proteins of human FBXO6 protein have been found using the service in the study.
Fbs2 is a novel member of F-box protein family that recognizes N-glycans and plays a role in ERAD
Fbx6-dependent Chk1 degradation contributes to S phase checkpoint termination and that a defect in this mechanism might increase tumor cell resistance to certain anticancer drugs.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
F-box only protein 6
, F-box protein FBG2
, F-box protein Fbx6
, F-box protein that recognizes sugar chains 2
, F-box/G-domain protein 2
, F-box only protein 6b
, F-box only protein 6 b
, F-box protein 6
, F-box protein 44