F-Box Protein 7 (FBXO7) ELISA Kits

FBXO7 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 7 Antibodies (33) and F-Box Protein 7 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FBXO7 25793 Q9Y3I1
FBXO7 69754 Q3U7U3
FBXO7 366854 Q68FS3
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Top F-Box Protein 7 ELISA Kits at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Human 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details
Pig
  96 Tests 15 to 18 Days
$707.14
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Chicken
  96 Tests 15 to 18 Days
$707.14
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Goat
  96 Tests 15 to 18 Days
$707.14
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Rabbit
  96 Tests 15 to 18 Days
$707.14
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Guinea Pig
  96 Tests 15 to 18 Days
$707.14
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Monkey
  96 Tests 15 to 18 Days
$707.14
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More ELISA Kits for F-Box Protein 7 Interaction Partners

Zebrafish F-Box Protein 7 (FBXO7) interaction partners

  1. analysis of the zebrafish model of Fbxo7 mutations with a role in levodopa-responsive parkinsonism with severe loss of nigrostriatal dopaminergic neurons

Human F-Box Protein 7 (FBXO7) interaction partners

  1. Results suggest that FBXO7 gene doesn't seem to be a risk factor to develop sporadic Parkinson's disease in Chinese population.

  2. The pathological mechanisms concerning FBXO7-relevant protein aggregation, mitochondria impairment, reactive oxygen species (ROS) generation and mitophagy modulation in PARK15 pathogenesis are highlighted and discussed in the current review.

  3. we highlight the recent research on FBXO7, which advances our knowledge of the etiopathological pathways and fills unexpected gaps therein, justifying the dedicated study of rare variants of Parkinson disease--{REVIEW}

  4. Fbxo7 deficiency is associated with reduced cellular NAD(+) levels, which results in increased mitochondrial NADH redox index and impaired activity of complex I in the electron transport chain.

  5. Structure and function of Fbxo7 in Parkinson's disease has been summarized. (Review)

  6. Gsk3beta and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

  7. Mutations in the F-box only protein 7 (FBXO7) gene, located on chromosome 22q12-q13, have been identified as having distinct clinical features in patients with hereditary Parkinson's disease (PD).

  8. The mutations of F-box protein 7 (FBXO7) gene (T22M, R378G and R498X) are associated with autosomal recessive juvenile-onset Parkinson's disease We demonstrated wild-type FBXO7 is a stress response protein with both cytoprotective and neurotoxic roles

  9. This is first time a FBXO7 mutation has been identified that causes phenotype compatible with typical idiopathic Parkinson's disease and presents with some of its common nonmotor features

  10. High expression of PARK15 might lead to the occurrence of non-small-cell lung cancer.

  11. genetic analysis of this Turkish family and the Italian PARK15 family reported previously revealed that the c.1492C > T mutation is present on two different haplotypes in the Italian family

  12. in addition to the parkinsonian-pyramidal phenotype, in connection with FBXO7 mutations and points to an intrafamilial phenotypic variation

  13. Cys52 variant of FBXO7 may contribute to reduced Parkinson's disease susceptibility in Chinese

  14. The involvement of the FBXO7 gene in PD is very rare, at least in this population from southern Spain.

  15. The crystal structure of the Fbxo7 FP domain is reported at 2.0 A resolution. The Fbxo7 FP domain adopts an alpha/beta-fold similar to that of the PI31 FP domain.

  16. A mutational analysis of the FBXO7 gene in Taiwanese patients with Parkinson's disease (PD) does not show a potential pathophysiological role in PD.

  17. This study showed that Fbxo7 participates in mitochondrial maintenance through direct interaction with PINK1 and Parkin and acts in Parkin-mediated mitophagy.

  18. An important role is suggested for FBXO7 in the pathogenesis of synucleinopathies, including Parkinson's disease and multiple system atrophy.

  19. Mutations in FBX07 is often associated with rapidly progressive parkinsonism and with additional features including pyramidal signs, cognitive decline and loss of sustained Levodopa responsiveness.

  20. analysis of the zebrafish model of Fbxo7 mutations with a role in levodopa-responsive parkinsonism with severe loss of nigrostriatal dopaminergic neurons

Mouse (Murine) F-Box Protein 7 (FBXO7) interaction partners

  1. Fbxo7 hypomorphs were produced at a normal Mendelian ratio with a normal lifespan and no evidence of neurological symptoms. These data suggest that erythrocyte survival, T cell development and spermatogenesis are particularly sensitive to Fbxo7 gene dosage.

  2. Fbxo7-deficient immature thymocytes failed to undergo expansion in the thymus due to a lack of Cdk6 activity, while mature T cells showed enhanced proliferative capacity upon T-cell receptor engagement due to reduced p27 levels. These studies reveal differential cell cycle regulation by Fbxo7 at different stages in T-cell development.

  3. Taken together, this study establishes a vital role for FBXO7 in neurons, which is required for proper motor control and accentuates the importance of FBXO7 in proteasome function.

  4. Report defective erythropoiesis in transgenic mouse with reduced Fbxo7 expression due to decreased erythrocyte p27 expression.

  5. 2 PDX models showed gained mutations such as PIK3CA or FBWX7 mutation. Ten patient-derived advanced colon cancer xenograft models were established.

  6. The physiological effect of reduced levels of Fbxo7 in mice showed significantly increased pro-B cell and pro-erythroblast populations, consistent with Fbxo7 having an anti-proliferative function and/or a role in promoting maturation of precursor cells.

  7. Fbxo7 specifically regulated D cyclin/cdk6 complexes; it was highly expressed in epithelial tumors, but not in normal tissues, suggesting that it may have a proto-oncogenic role in human cancers.

F-Box Protein 7 (FBXO7) Antigen Profile

Antigen Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Gene names and symbols associated with F-Box Protein 7 (FBXO7) ELISA Kits

  • F-box protein 7 (FBXO7) antibody
  • F-box protein 7 L homeolog (fbxo7.L) antibody
  • F-box protein 7 (fbxo7) antibody
  • F-box protein 7 (FBP7) antibody
  • F-box protein 7 (Fbxo7) antibody
  • 2410015K21Rik antibody
  • A230052G17Rik antibody
  • AI117679 antibody
  • ATFBP7 antibody
  • AW260462 antibody
  • C85118 antibody
  • DKFZp469H0739 antibody
  • F-box protein 7 antibody
  • F8K7.20 antibody
  • F8K7_20 antibody
  • FBX antibody
  • FBX07 antibody
  • FBX7 antibody
  • FBXO7 antibody
  • MGC80085 antibody
  • MGC135804 antibody
  • MGC145325 antibody
  • PARK15 antibody
  • PKPS antibody
  • si:ch211-286m4.2 antibody
  • zgc:114096 antibody

Protein level used designations for F-Box Protein 7 (FBXO7) ELISA Kits

F-box only protein 7 , F-box protein 7 , F-box only protein 7-like

GENE ID SPECIES
418063 Gallus gallus
474522 Canis lupus familiaris
446503 Xenopus laevis
470266 Pan troglodytes
717317 Macaca mulatta
780025 Xenopus (Silurana) tropicalis
838780 Arabidopsis thaliana
100016137 Monodelphis domestica
100135459 Papio anubis
100172444 Pongo abelii
100409679 Callithrix jacchus
100595350 Nomascus leucogenys
558097 Danio rerio
25793 Homo sapiens
100155281 Sus scrofa
508235 Bos taurus
100328739 Oryctolagus cuniculus
69754 Mus musculus
366854 Rattus norvegicus
101118684 Ovis aries
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