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Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXL17 Kits (12) and FBXL17 Proteins (5) and many more products for this protein.
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In summary, these findings reveal Fbxl17 as a novel regulator of the Hedgehog signaling pathway and highlight the perturbation of the Fbxl17-Sufu axis in the pathogenesis of medulloblastoma.
Identify a role for SCF(FBXL17) in controlling the threshold for NRF2-dependent gene activation via BACH1 repressor turnover.
F-box protein 17 (FBXL17) can serve as a therapeutic target and surrogate marker for breast cancer therapy.
F-box protein FBL17 acts as a master cell cycle regulator during the diploid sporophyte phase of the plant.
FBL17 is involved in cell cycle regulation during male gametogenesis. Loss-of-function mutants fail to undergo pollen mitosis II.
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box only protein 13
, F-box/LRR-repeat protein 17
, F-box and leucine-rich repeat protein 17
, F-box/LRR-repeat protein 17-like
, f-box/LRR-repeat protein 17-like