FBXW4 Proteins

FBXW4 is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation.

Data Quality
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3130394
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3080125
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1353871
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman, Monkey, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2750001
$318.85
5 applications
Plus shipping costs $45.00
Delivery in 1 to 2 Business Days
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FBXW4 Protein Profile

Protein Summary

This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds\; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.

Gene names and symbols associated with FBXW4

  • F-box and WD repeat domain containing 4 (fbxw4) antibody
  • F-box and WD repeat domain containing 4 (FBXW4) antibody
  • F-box and WD repeat domain containing 4 (Fbxw4) antibody
  • F-box and WD-40 domain protein 4 (Fbxw4) antibody
  • Dac antibody
  • dactylin antibody
  • dactylyn antibody
  • Fbw4 antibody
  • FBWD4 antibody
  • FBXW4 antibody
  • hag antibody
  • hagoromo antibody
  • SHFM3 antibody
  • SHSF3 antibody
  • wu:fk63g06 antibody

Protein level used designations for FBXW4

F-box/WD repeat-containing protein 4 , dactylaplasia , fk63g06 , F-box and WD repeat domain containing 4 , F-box and WD-40 domain protein 4 , F-box and WD-40 domain-containing protein 4 , F-box/WD repeat protein 4 , dactylin , F-box protein Fbw4 , protein hagoromo

GENE ID SPECIES
58035 Danio rerio
450689 Pan troglodytes
6468 Homo sapiens
309444 Rattus norvegicus
100721914 Cavia porcellus
101113450 Ovis aries
30838 Mus musculus
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