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Required for eye and embryo development, and plays a role in compound eye assembly and oogenesis respectively.
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Results indicate that the ability of faf, hiw or Rdl (show LEO1 Antibodies) to modulate sleep and protect against cognitive impairments during waking is circuit dependent. Decreasing hiw and Rdl (show LEO1 Antibodies) within the Mushroom Bodies protects against the negative effects of sleep deprivation as indicated by the absence of a subsequent homeostatic response, or deficits in short-term memory.
Faf inhibits the IMD (show ADM2 Antibodies) pathway by modulating the state of Imd (show ADM2 Antibodies) ubiquitination and/or stability.
Fat facets deubiquitylation of Medea/Smad4 modulates interpretation of a Dpp morphogen gradient
By deubiquitinating Lqf, which enhances the efficiency of Delta internalization, Faf stimulates Delta signaling
Required for eye and embryo development, and plays a role in compound eye assembly and oogenesis respectively. In the larval eye disks, cells outside the assembling facets require this protein for short-range cell interactions that prevent the mystery cells from becoming photoreceptors. It is also required for nuclear migration and cellularization in early embryogenesis and could play a role in pole cell determination, development or function.
, Fat facets