FCH Domain Only 2 (FCHO2) ELISA Kits

Functions in an early step of clathrin-mediated endocytosis. Additionally we are shipping FCHO2 Antibodies (32) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FCHO2 115548 Q0JRZ9
FCHO2 218503 Q3UQN2
Anti-Rat FCHO2 FCHO2 309129  
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Top FCHO2 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 15 to 18 Days
$875.60
Details
Mouse
  96 Tests 15 to 18 Days
$875.60
Details

More ELISA Kits for FCHO2 Interaction Partners

Human FCH Domain Only 2 (FCHO2) interaction partners

  1. Fcho1/2Eps15/RAP-2 ternary complexes to facilitate conformational activation of AP-2 by the Fcho1/2 interdomain linker to promote AP-2 cargo engagement.

  2. The central linker of FCHO proteins acts as an allosteric regulator of the prime endocytic adaptor, AP-2.

  3. FCHO2 regulates the size of clathrin structures, and its interaction with Dab2 is needed for LDLR endocytosis under conditions of low AP2.

  4. show that the mu-homology domain of FCHO1/2 represents an endocytic interaction hub

  5. This structure shows a distant relationship to curvature-sensing BAR modules, and suggests how similar coiled-coil architectures in the BAR superfamily have evolved to expand the repertoire of membrane-sculpting possibilities

Mouse (Murine) FCH Domain Only 2 (FCHO2) interaction partners

  1. FCHO2 regulates clathrin-mediated endocytosis through its interactions with membranes and Eps15.

  2. study reports FCHo1/2 were required for plasma membrane clathrin-coated vesicle (CCV) budding & marked sites of CCV formation

FCHO2 Antigen Profile

Antigen Summary

Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP- 2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.

Gene names and symbols associated with FCH Domain Only 2 (FCHO2) ELISA Kits

  • FCH domain only 2 (FCHO2) antibody
  • FCH domain only 2 (fcho2) antibody
  • FCH domain only 2 (Fcho2) antibody
  • 5832424M12Rik antibody
  • AA387320 antibody
  • cb304 antibody
  • RGD1565396 antibody
  • sb:cb304 antibody
  • wu:fa01a02 antibody
  • zgc:112167 antibody

Protein level used designations for FCH Domain Only 2 (FCHO2) ELISA Kits

FCH domain only 2 , FCH domain only protein 2

GENE ID SPECIES
471520 Pan troglodytes
478094 Canis lupus familiaris
540808 Bos taurus
702506 Macaca mulatta
100012377 Monodelphis domestica
100065702 Equus caballus
100216087 Xenopus (Silurana) tropicalis
100218413 Taeniopygia guttata
100412087 Callithrix jacchus
100552055 Anolis carolinensis
100589844 Nomascus leucogenys
115548 Homo sapiens
218503 Mus musculus
309129 Rattus norvegicus
553949 Danio rerio
100173197 Pongo abelii
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