FCHO2 Products
(FCH Domain Only 2 (FCHO2))
Categories
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP- 2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
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Featured FCHO2 Categories
FCHO2 Antibodies
High quality antibodies with extensive validation data.
FCHO2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended FCHO2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7152394
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN1537842
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN1449925
Quantity
0.1 mg
Datasheet
Datasheet
Recommended FCHO2 ELISA Kits
Recommended FCHO2 Proteins
Latest Publications for our FCHO2 products
: "A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation." in: eLife, Vol. 8, (2019) (PubMed).: "Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells." in: Nature cell biology, Vol. 19, Issue 4, pp. 352-361, (2017) (PubMed).
Synonyms and alternative names related to FCHO2
FCH domain only 2 (FCHO2), FCH domain only 2 (fcho2), FCH domain only 2 (Fcho2), 5832424M12Rik, AA387320, cb304, RGD1565396, sb:cb304, wu:fa01a02, zgc:112167Protein level used designations for FCHO2
- FCH domain only 2
- FCH domain only protein 2
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