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Rho-guanine nucleotide exchange factor that activates RAC1.
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FRG is a member of Cdc42-GEF and plays an important role in the signaling pathway downstream of G protein-coupled receptors
Findings reveal an integral role of FARP2 for regulation of Rac1 and integrin beta3 throughout podosome rearrangement in osteoclastogenesis.
Developmental regulation of FERM domain including guanine nucleotide exchange factor (show ARHGEF12 Antibodies) gene expression in the mouse brain.
Confirmed Hdlq14 as a separate independent quantitative trait locus for HDL (show HSD11B1 Antibodies) and narrowed the region to 2 genes, Farp2 and Stk25 (show STK25 Antibodies), with considerable evidence for both.
Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton (By similarity).
FERM, RhoGEF and pleckstrin domain protein 2
, FERM, RhoGEF and pleckstrin domain-containing protein 2-like
, FERM domain including RhoGEF
, FERM, RhoGEF and pleckstrin domain-containing protein 2
, FGD1-related Cdc42-GEF
, PH domain-containing family C member 3
, pleckstrin homology domain-containing family C member 3