anti-FOS-Like Antigen 1 (FOSL1) Antibodies

The Fos gene family consists of 4 members FOSL1, and FOSL2. Additionally we are shipping FOSL1 Kits (22) and FOSL1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FOSL1 8061 P15407
FOSL1 14283 P48755
FOSL1 25445 P10158
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Top anti-FOSL1 Antibodies at

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Host: Rat Target Name: FOSL1 Sample Tissue: Rat Skeletal Muscle Antibody Dilution: 1ug/ml Human Skin 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Lung tissue at an antibody concentration of 5µg/ml using anti-FOSL1 antibody (ARP31378_P050) WB Suggested Anti-FOSL1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN185649 (1µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6269884 at 1/100 staining mouse liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269884 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of FOSL1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of FOSL1 expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT-29 cells, using Fra-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with FOSL1 antibody ABIN462165 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-FOSL1 / FRA1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Othe ... 50 μg Log in to see 11 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Phospho-FRA1 (Ser265) in lysates of HT29, using Phospho-FRA1 (Ser265) Antibody(ABIN6268029). 100 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days

Top referenced anti-FOSL1 Antibodies

  1. Cow (Bovine) Polyclonal FOSL1 Primary Antibody for IHC, WB - ABIN2777265 : Debinski, Gibo: Fos-related antigen 1 modulates malignant features of glioma cells. in Molecular cancer research : MCR 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal FOSL1 Primary Antibody for ELISA, WB - ABIN251492 : Belguise, Kersual, Galtier, Chalbos: FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells. in Oncogene 2005 (PubMed)

  3. Human Polyclonal FOSL1 Primary Antibody for ICC, IHC - ABIN1858911 : Witusik-Perkowska, Zakrzewska, Sikorska, Papierz, Jaskolski, Szemraj, Liberski: Glioblastoma-derived cellsin vitrounveil the spectrum of drug resistance capability - comparative study of tumour chemosensitivity in different culture systems. in Bioscience reports 2017 (PubMed)

More Antibodies against FOSL1 Interaction Partners

Human FOS-Like Antigen 1 (FOSL1) interaction partners

  1. High FOS-like antigen 1 (FOSL1) expression with mutant KRAS protein lung and pancreatic cancer patients showed the worst survival outcome.

  2. Our findings indicated that functional SNP rs1892901 in FOSL1 might affect the expression of FOSL1, and ultimately increase the risk of gastric cancer.

  3. Fra1 inhibited the protein levels of Bcl2, cMyc, Survivin, and BclxL. Fra1 overexpression in intestinal mucosal epithelial cells may restrain damage repair after intestinal mucosal injury in inflammatory bowel disease remittent period through weakening the protective effect of intestinal mucosa, thus increasing the risk of recurrence.

  4. High FRA1 expression is associated with Esophageal Squamous Cell Carcinoma.

  5. constitutive activation and non-regulation of Fra-1 by bicalutamide in PC-3 cells suggested that Fra-1, probably a key component, involved in transition of aggressive androgen-independent PC-3 cells with poor prognosis.

  6. the overexpression of Fra1 disrupted inflammatory cytokine secretion by medullary thymic epithelial cells in the myasthenia gravis thymus

  7. Taken together, our results indicated that miR-449 overexpression inhibited osteogenic differentiation of HG-FFA-treated hBMSCs through the Sirt1/Fra-1 signal pathway.

  8. These findings indicate that an aberrant Wnt/beta-catenin signalling leads to the epithelial-mesenchymal transition and drug resistance of glioma via Fra1 induction, which suggests novel therapeutic strategies for the malignant disease.

  9. MUC1 enhancement of ERK activation influences FRA-1 activity to modulate tumor migration, invasion and metastasis in a subset of pancreatic cancer cases

  10. the results indicate that FRA1 promotes cancer growth through AKT, and enhances cancer cell migration through JNK/c-Jun, pinpointing FRA1 as a key integrator of JNK and AKT signaling pathways and a potential therapeutic target for squamous cell carcinoma of the skin and head and neck squamous cell carcinoma.

  11. Study shows that FOSL1 is the main immediate early AP-1 member induced by melanoma oncogenes; found that FOSL1 is involved in melanoma cell migration as well as cell proliferation and anoikis-independent growth.

  12. a Fra-1-miR-134 axis drives a positive feedback loop that amplifies ERK/JNK signaling and reduces chemosensitivity in ovarian cancer cells.

  13. PKCtheta;-induced phosphorylations control the ability of Fra-1 to stimulate gene expression and breast cancer cell migration.

  14. Multivariate analysis identified Fra-1 as an independent prognostic factor. Fra-1 may be involved in the progress of hepatocellular carcinoma and could be a promising molecular candidate in the diagnosis and treatment of hepatocellular carcinoma.

  15. Up-regulation of Fra-1 appeared in retinal ganglion cells following light-induced retina damage.

  16. HGF-induced FRA1 activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.

  17. Our results demonstrate that Fra-1 is an important determinant of the metastatic potential of human colon cancer cells, and that the Fra-1 classifier can be used as a prognostic predictor in colon cancer patients.

  18. Results suggest that Fra-1 is upregulated in lung cancer tissues and functions by affecting the P53 signaling pathway.

  19. SIRT1 expression correlated positively with Fra-1 expression, metastasis and overall survival in patients with colorectal cancer

  20. We identified and confirmed that Fra-1 affected the expression level of CTTN and EZR in vitro through LC-MS/MS analyses and western blot technology.

Mouse (Murine) FOS-Like Antigen 1 (FOSL1) interaction partners

  1. NF-kappaB and c-Jun coregulate lipopolysaccharide-induced Fra-1 transcription.

  2. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3), TIR domain-containing adapter inducing IFN-beta (TRIF), and Tank-binding kinase 1 (TBK1) via impairing K63-linked polyubiquitination of TRAF3 and TRIF.

  3. Adipose-derived stromal cells overexpressing Fra-1 effectively protect against osteoarthritis.

  4. Overexpression of Fosl1, which encodes a component of the AP-1 transcription factor complex, in osteoblasts significantly blocked malleal capillary narrowing.

  5. Fra-1 gene expression is activated in response lipopolysaccharide induced lung-injury in mice.

  6. Data suggest that expression of Fra1 (fos-related antigen 1) in preadipocytes is up-regulated by arachidonic acid (AA) during late stages of adipogenesis; however, in early stage of adipogenesis, AA inhibits adipogenesis via Fra1-dependent mechanism.

  7. Fra-1 plays a key role in promoting chronic CS-induced lung macrophagic inflammation in vivo

  8. we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 expression.

  9. observations suggest that MyoD and pRb work together cooperatively at the level of the intronic enhancer of Fra-1 during terminal cell cycle arrest

  10. findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib loss activates a MAPK/Fra1 pathway that alters mammary progenitor activity

  11. findings support the hypothesis that miR-19a-3p, which regulates tumor-associated macrophages(TAMs)in the breast tumor microenvironment,is able to regulate the phenotype of TAMs by targeting the Fra-1 gene and other genes in its downstream signaling pathway

  12. modulates the expression of detoxification genes and the adaptive response of the liver to bile acids/xenobiotic overload

  13. these results indicate that Fra-1 is a direct target of Runx2 during osteogenic differentiation of C2C12 myogenic progenitor cells.

  14. Fra-1 mediates anti-fibrotic effects in the lung through the modulation of proinflammatory, profibrotic and fibrotic gene expression.

  15. data suggest the involvement of an injury-induced Fra-1 transcription factor as a regulator of keratinocyte gene expression, which might act as an antagonistic player to restrict epithelial-driven angiogenic responses during normal skin flap integration.

  16. FRA-1, induced in response to estrogen signaling via ESR1, is a key regulator of stromal differentiation and remodeling during early pregnancy.

  17. Fra-1 (Delta/Delta) mice showed a greater resistance to LPS-induced mortality than did their Fra-1(+/+) counterparts.

  18. Fra-1 is an important mediator of interstitial lung disease following gefitinib treatment

  19. Cebpa was downregulated in the Fra-1-overexpressing cells and Fra-1 could bind to the Cebpa promoter and directly suppress its activity.

  20. Fra-1tg mice spontaneously develop a progressive biliary disease.

FOSL1 Antigen Profile

Protein Summary

The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Gene names and symbols associated with FOSL1

  • FOS like 1, AP-1 transcription factor subunit (FOSL1) antibody
  • fos-like antigen 1 (Fosl1) antibody
  • FOS like 1, AP-1 transcription factor subunit (Fosl1) antibody
  • FOS-like antigen 1a (fosl1a) antibody
  • AW538199 antibody
  • fosl1 antibody
  • FRA antibody
  • Fra-1 antibody
  • Fra1 antibody
  • sb:eu506 antibody
  • si:ch211-145o7.4 antibody

Protein level used designations for FOSL1

FOS-like antigen-1 , fos-related antigen 1 , FOS-like antigen 1

8061 Homo sapiens
483724 Canis lupus familiaris
531389 Bos taurus
14283 Mus musculus
25445 Rattus norvegicus
100734428 Cavia porcellus
101111137 Ovis aries
564241 Danio rerio
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