FXYD Domain Containing Ion Transport Regulator 3 Proteins (FXYD3)

Human FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

1. Suppression of FXYD3 in MCF-7.

2. Study demonstrated that the expression of FXYD1 (show FXYD1 Proteins), FXYD3 and FXYD5 (show FXYD5 Proteins) is elevated in the lungs of Acute respiratory distress syndrome patients

3. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (show S100A11 Proteins) (p = 0.0071), and GSTM3 (show GSTM3 Proteins) (p = 0.0173) in colon cancer lymphatic metastasis.

4. ExoS facilitates P. aeruginosa penetration through the intestinal epithelial barrier by binding to FXYD3 and thereby impairing the defense function of tight junctions against bacterial penetration.

5. Up-regulated expression of FXYD-3 protein may be involved in tumourgenesis and invasion of gastric adenocarcinoma.

6. FXYD3 expression is related to several biological variables including ras, p53 (show TP53 Proteins), legumain (show LGMN Proteins) and PCNA (show PCNA Proteins), and may be involved in the development of the relatively early stages of colorectal cancers

7. Upregulation of FXYD3 is associated with glioma.

8. inactivation of FXYD3 through a gene mutation or unknown mechanism could be one cause of the atypical shapes of cancer cells and play a potential role in the progression of lung cancer.

9. Results indicate that the human MAT-8 gene contains the potential to serve as a prostate cancer expression marker and that MAT-8 plays an important role in cellular growth of prostate carcinomas.

10. overexpression of FXYD3 in pancreatic cancer may contribute to the proliferative activity of this malignancy

Mouse (Murine) FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

1. Because gluco-incretin secretion depends on feeding the epigenetic regulation of Fxyd3 expression may link nutrition in early life to establishment of adult beta-cell glucose competence.

2. Fxyd3 and Lgi4 transcripts potentially form double-stranded RNA molecules in many cell types in vivo, which may impact on their respective expression

3. regulator of Na,K-ATPase (show ATP1A1 Proteins)