FXYD Domain Containing Ion Transport Regulator 3 Proteins (FXYD3)

FXYD3 belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. Additionally we are shipping FXYD Domain Containing Ion Transport Regulator 3 Antibodies (29) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FXYD3 5349 Q14802
FXYD3 17178 Q61835
Rat FXYD3 FXYD3 116831 P59645
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Top FXYD Domain Containing Ion Transport Regulator 3 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
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Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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FXYD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) Interaction Partners

Human FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

  1. Scn1b and Fxyd1 expression was significantly downregulated in HSCR colon.

  2. Suppression of FXYD3 in MCF-7.

  3. Study demonstrated that the expression of FXYD1, FXYD3 and FXYD5 is elevated in the lungs of Acute respiratory distress syndrome patients

  4. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (p = 0.0071), and GSTM3 (p = 0.0173) in colon cancer lymphatic metastasis.

  5. ExoS facilitates P. aeruginosa penetration through the intestinal epithelial barrier by binding to FXYD3 and thereby impairing the defense function of tight junctions against bacterial penetration.

  6. Up-regulated expression of FXYD-3 protein may be involved in tumourgenesis and invasion of gastric adenocarcinoma.

  7. FXYD3 expression is related to several biological variables including ras, p53, legumain and PCNA, and may be involved in the development of the relatively early stages of colorectal cancers

  8. Upregulation of FXYD3 is associated with glioma.

  9. inactivation of FXYD3 through a gene mutation or unknown mechanism could be one cause of the atypical shapes of cancer cells and play a potential role in the progression of lung cancer.

  10. molecular cloning, protein expression, sequencing and NMR structure determination

  11. Results indicate that the human MAT-8 gene contains the potential to serve as a prostate cancer expression marker and that MAT-8 plays an important role in cellular growth of prostate carcinomas.

  12. overexpression of FXYD3 in pancreatic cancer may contribute to the proliferative activity of this malignancy

  13. show that the helical regions and connecting segments of FXYD1, FXYD3, and FXYD4 determined in micelles by NMR spectroscopy coincide with the positions of intron-exon junctions in the genes

  14. analysis of two human FXYD3 isoforms that are differentially expressed in differentiated and non-differentiated cells with different functional properties

  15. FXYD3 interacts with Na(+)-K(+)-Exchanging ATPase in colorectal neoplasms.

  16. structures of the FXYD proteins (with emphasis on 1-4), as well as their dynamics and their associations with the lipid

  17. FXYD3 silencing prevents proper regulation of Na,K-ATPase, which leads to perturbation of cellular Na+ and K+ homeostasis and changes in the expression of Na,K-ATPase isozymes, whose functional properties are incompatible with cell differentiation.

  18. FXYD3a protein is highly expressed in breast cancers, and responsible for cancer cell proliferation.

Mouse (Murine) FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) interaction partners

  1. Because gluco-incretin secretion depends on feeding the epigenetic regulation of Fxyd3 expression may link nutrition in early life to establishment of adult beta-cell glucose competence.

  2. Fxyd3 and Lgi4 transcripts potentially form double-stranded RNA molecules in many cell types in vivo, which may impact on their respective expression

  3. regulator of Na,K-ATPase

FXYD Domain Containing Ion Transport Regulator 3 (FXYD3) Protein Profile

Protein Summary

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with FXYD3

  • FXYD domain containing ion transport regulator 3 (FXYD3)
  • FXYD domain-containing ion transport regulator 3 (Fxyd3)
  • FXYD3 protein
  • MAT-8 protein
  • Mat8 protein
  • PLML protein

Protein level used designations for FXYD3

FXYD domain containing ion transport regulator 3 , FXYD domain-containing ion transport regulator 3 , chloride conductance inducer protein Mat-8 , mammary tumor 8 kDa protein , phospholemman-like protein

GENE ID SPECIES
612671 Canis lupus familiaris
707346 Macaca mulatta
744576 Pan troglodytes
780807 Bos taurus
5349 Homo sapiens
397413 Sus scrofa
17178 Mus musculus
116831 Rattus norvegicus
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