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Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis (By similarity).. Additionally we are shipping and many more products for this protein.
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EVA1A interacts with the WD repeats of ATG16L1 (show ATG16L1 Antibodies) through its C-terminal and promotes ATG12 (show ATG12 Antibodies)-ATG5 (show ATG5 Antibodies)/ATG16L1 (show ATG16L1 Antibodies) complex recruitment to the autophagic membrane and enhances the formation of the autophagosome.
Low EVA1A expression is associated with glioblastoma.
The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells.
TMEM166 expression was widely down-regulated in the cancer tissues.
Low TMEM166 mRNA and protein expression is associated with esophageal squamous cell carcinoma.
TMEM166 is a novel regulator involved in both autophagy and apoptosis.
Eva1a improves cardiac function.
ATP synthesis, oxidative phosphorylation, and the TCA cycle, are involved in the EVA1A regulatory network.EVA1A plays an important role in neuronal differentiation.
EVA1A deletion results in defective self-renewal and differentiation of NSCs. EVA1A modulates autophagy through the PIK3CA (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway.
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis (By similarity).
family with sequence similarity 176, member A
, protein FAM176A
, transmembrane protein 166
, protein eva-1 homolog A