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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping Fanconi Anemia, Complementation Group B Antibodies (45) and many more products for this protein.
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Four single nucleotide polymorphisms were identified, three of which were located in untranslated regions of Fanconi anemia group B protein (FANCB) and predicted to be associated with normal function.
Loss-of-function FANCB (show BRCA2 Proteins) mutations result in a recognizable, multiple malformation phenotype in hemizygous males for which we propose clinical criteria to aid diagnosis.
Inactivation of FancB (show BRCA2 Proteins) may play a role in the pathogenesis of sporadic HNSCC.
Elevated serum FA-2 was associated with bony metastases from breast cancer.
the protein defective in individuals with Fanconi anemia belonging to complementation group B is an essential component of the nuclear protein 'core complex' responsible for monoubiquitination of FANCD2
summary of recent advances in the Fanconi anemia (show PALB2 Proteins)-BRCA network with emphasis on the new discovery of FAAP95 as the true FANCB (show BRCA2 Proteins) gene [review]
Mutations in FANCB (show BRCA2 Proteins) are a cause of X linked VACTERL-H syndrome.
Mus81 (show MUS81 Proteins) and FANCB (show BRCA2 Proteins) have different roles in repair of DNA damage during replication in human cells
Our results rule out a major contribution of FANCB (show BRCA2 Proteins) to hereditary breast cancer.
Data suggest that Fanconi anemia complementation group B protein (show LEPREL2 Proteins) Fancb(-/y) mouse model for studying the Fanconi anemia (show PALB2 Proteins) (FA) pathway not only in germ cell development but also in the maintenance of hematopoietic stem cell (HSC (show FUT1 Proteins)) function.
FANCB functions at critical stages of germ cell development and reveal a novel function of the FA pathway in the regulation of H3K9 methylation in the germline.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.
Fanconi anemia group B protein
, Fanconi anemia-associated polypeptide of 95 kDa
, Fanconi anemia group B protein homolog