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anti-Fanconi Anemia, Complementation Group E (FANCE) Antibodies

FANCE encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2. Additionally we are shipping Fanconi Anemia, Complementation Group E Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FANCE 2178 Q9HB96
FANCE 72775  
FANCE 309643  
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Top anti-Fanconi Anemia, Complementation Group E Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FANCE Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$319.00
Details
Human Goat Un-conjugated ELISA, IHC   100 μg 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA Immunohistochemistry (3.8μg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Anti-FANCE antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1101477 concentration 27454 ug/ml. Anti-FANCE antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$537.17
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Cow Goat Un-conjugated EIA, IHC (p) FANCE Antibody  staining of paraffin embedded Human Placenta at 3.8 μg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg 6 to 8 Days
$445.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of mouse thymus cells, using FANCE antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated EIA   0.1 mg 6 to 8 Days
$594.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details

Top referenced anti-Fanconi Anemia, Complementation Group E Antibodies

  1. Human Polyclonal FANCE Primary Antibody for ELISA, IHC - ABIN4310515 : Barroso, Pita, Arias, Menendez, Zamora, Blanco, Benitez, Ribas: The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features. in Breast cancer research and treatment 2009 (PubMed)

More Antibodies against Fanconi Anemia, Complementation Group E Interaction Partners

Human Fanconi Anemia, Complementation Group E (FANCE) interaction partners

  1. A novel alternative splicing event of the FANCE gene has been characterized. FANCEDelta4 cannot support the activation of the FANC-BRCA pathway and DNA repair.

  2. a phenylalanine located at the highly conserved extreme C terminus, referred to as Phe-522, is a critical residue for mediating the monoubiquitination of the FANCD2-FANCI complex.

  3. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.

  4. This Fanconi anemia protein promotes the nuclear accumulation of FANCC.

  5. FANCC, FANCE, and FANCD2 form a ternary complex in the Fanconi anemia DNA damage response pathway

  6. nuclear accumulation of FANCE does not rely solely on its nuclear localization signal motifs, but also on FANCC

  7. Chk1-mediated phosphorylation of FANCE is required for a function independent of FANCD2 monoubiquitination.

  8. Disease-associated mutations disrupt the FANCE-FANCD2 interaction, providing structural insight into the molecular mechanisms of Fanconi Anaemia pathogenesis.

Mouse (Murine) Fanconi Anemia, Complementation Group E (FANCE) interaction partners

  1. Results provide evidence that fance protein plays an important, but not absolutely essential, role in the initial developmental expansion of the male germ line.

  2. Primary ovarian insufficiency is induced by Fance mutation in a mouse model.

  3. The fact that defects in the human ortholog result in Fanconi anemia disease suggests that this protein has a critical function and is likely evolutionarily conserved.

Fanconi Anemia, Complementation Group E (FANCE) Antigen Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.

Gene names and symbols associated with FANCE

  • Fanconi anemia complementation group E (FANCE) antibody
  • Fanconi anemia, complementation group E (fance) antibody
  • Fanconi anemia complementation group E (fance) antibody
  • Fanconi anemia, complementation group E (FANCE) antibody
  • Fanconi anemia, complementation group E (Fance) antibody
  • 2810451D06Rik antibody
  • AI415634 antibody
  • AW209126 antibody
  • FACE antibody
  • FAE antibody
  • FANCE antibody
  • RGD1561045 antibody

Protein level used designations for FANCE

Fanconi anemia, complementation group E , Fanconi anemia E , Fanconi anemia group E protein , fanconi anemia group E protein-like , Fanconi anemia group E protein-like

GENE ID SPECIES
419891 Gallus gallus
565685 Danio rerio
747546 Pan troglodytes
100126687 Xenopus (Silurana) tropicalis
100400262 Callithrix jacchus
100446212 Pongo abelii
2178 Homo sapiens
608172 Canis lupus familiaris
513464 Bos taurus
72775 Mus musculus
309643 Rattus norvegicus
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