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FUBP1 encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Additionally we are shipping Far Upstream Element (FUSE) Binding Protein 1 Antibodies (82) and Far Upstream Element (FUSE) Binding Protein 1 Proteins (10) and many more products for this protein.
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High FUBP1 expression is associated with low Chemosensitivity to Adriamycin in Gastric Cancer.
Low FUBP1 expression is associated with adenovirus infection.
These results suggest that the interference with the FUBP1/FUSE interaction as a further molecular mechanism that, in addition to the inactivation of TOP1 (show TOP1 ELISA Kits), may contribute to the therapeutic potential of camptothecin/SN-38.
The findings demonstrate an association between FUBP1 levels and chordoma progression and prognosis, suggesting that FUBP1 can be used as a biomarker and a potential therapeutic target.
we identified cyclin J and far upstream element-binding protein 1 (FUBP1) as novel miR-16 (show GDE1 ELISA Kits) targets, which mediate miR-16 (show GDE1 ELISA Kits) antiproliferative effects.
FUBP1 acts as a potential oncogene (show RAB1A ELISA Kits) in clear cell renal cell carcinoma (show MOK ELISA Kits) (ccRCC) and may be considered as a novel biomarker or an attractive treatment target of ccRCC.
FBP1 (show FBP1 ELISA Kits) expression in Bcell lymphoma was also associated with poor survival outcomes. Functionally, small interfering RNAmediated silencing of FBP1 (show FBP1 ELISA Kits) was able to inhibit the proliferation of Bcell lymphoma cells, resulting in G0/G1 phase cell cycle arrest.
FUBP1 may potentially stimulate c-Myc (show MYC ELISA Kits) expression in ESCC and its expression may promote esophageal squamous cell carcinoma progression.
With the advent of large-scale genome sequencing technology, molecular genetic alterations in FUBP1 promoter have now been identified in the majority of oligodendrogliomas
direct connection between the cellular PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling pathway, frequently activated in human hepatocarcinogenesis, and the enrichment of oncogenic transcription factors of the FBP (show FBP1 ELISA Kits) family
FBP helps to hold multiple physiologic processes to close tolerances, at least in part by constraining Myc (show MYC ELISA Kits) expression.
Our data establish FUBP1 and its recognition of single-stranded genomic DNA as an important element in the transcriptional regulation of hematopoietic stem cells self-renewal.
Apoptosis-mediated cleavage of FBP1 (show FBP2 ELISA Kits) and its decreased expression in epithelial cells induces cell cycle arrest, which may play an important role in colonic epithelial disruption in colitis.
FUBP1 is an authentic substrate of Parkin (show PARK2 ELISA Kits) that might play an important role in development of Parkinson disease pathology along with aminoacyl-tRNA synthetase interacting multifunctional protein type 2
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
DNA helicase V
, far upstream element-binding protein 1
, hDH V
, far upstream element (FUSE) binding protein 1
, far upstream element-binding protein
, far upstream element-binding protein 1-like
, FUSE-binding protein 1
, far upstream element (FUSE) binding protein 4
, FUSE binding protein 1