anti-Fc Receptor, IgG, Low Affinity IV (FCGR4) Antibodies

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Additionally we are shipping Fc Receptor, IgG, Low Affinity IV Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FCGR4 246256 A0A0B4J1G0
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Top anti-Fc Receptor, IgG, Low Affinity IV Antibodies at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of mouse FCGR4 in mouse intestine with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of mouse FCGR4 in mouse liver with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 14 to 16 Days
$312.53
Details
Mouse Rabbit FITC FACS Flow cytometric analysis of FCGR4 expression on Raw264.7 cells. 50 Tests Log in to see 14 to 16 Days
$223.24
Details
Mouse Rabbit Un-conjugated ELISA, FACS, IF, IF/ICC Flow cytometric analysis of FCGR4 expression on Raw264.7 cells. Mouse leukaemic monocyte macrophage cell line RAW 264.7 were stained with anti-mouse FCGR4 (50036-R012, 1 μg/test), then a FITC-conjugated second step antibody. The histogram were derived fro Immunofluorescence staining of Mouse FcGR4 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse FcGR4 monoclonal antibody (10 µg/ml) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 48 100 μg Log in to see 14 to 16 Days
$312.53
Details
Mouse Rabbit APC FACS 50 Tests Log in to see 14 to 16 Days
$223.24
Details
Mouse Rabbit PerCP FACS Flow cytometric analysis of FCGR4 expression on Raw264.7 cells. 50 Tests Log in to see 14 to 16 Days
$223.24
Details
Mouse Rabbit PE FACS Flow cytometric analysis of FCGR4 expression on Raw264.7 cells. 50 Tests Log in to see 14 to 16 Days
$223.24
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 14 to 16 Days
$183.12
Details
Mouse Armenian Hamster Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$239.83
Details
Mouse Rat Un-conjugated IHC (fro), FACS   0.25 mg Log in to see 3 to 4 Days
$433.53
Details
Mouse Rat FITC FACS   0.1 mg Log in to see 3 to 4 Days
$364.94
Details

Top referenced anti-Fc Receptor, IgG, Low Affinity IV Antibodies

  1. Mouse (Murine) Monoclonal FCGR4 Primary Antibody for IHC (fro), FACS - ABIN2478683 : Harendza, Johnson: Polyadenylylation signal of the mouse thymidylate synthase gene was created by insertion of an L1 repetitive element downstream of the open reading frame. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Monoclonal FCGR4 Primary Antibody for FACS - ABIN2478684 : White, Chan, Roghanian, French, Mockridge, Tutt, Dixon, Ajona, Verbeek, Al-Shamkhani, Cragg, Beers, Glennie: Interaction with Fc?RIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Fc Receptor, IgG, Low Affinity IV Interaction Partners

Mouse (Murine) Fc Receptor, IgG, Low Affinity IV (FCGR4) interaction partners

  1. The IgG2 immune complexes activates osteoclastogenesis by binding to FcgammaRIThe IgG2 immune complexes activates osteoclastogenesis by binding to FcgammaRIV.

  2. antibody orchestrated Fcgamma receptor-mediated switch in inflammation is one mechanism underlying inhibition of axon regeneration

  3. The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.

  4. FcgammaRIV expression and function on osteoclasts during the steady state and during acute joint inflammation in a model of inflammatory arthritis

  5. The mechanism(s) of phagocytosis in the second phase of blood incompatibility reaction required neither C3 nor FcgammaRs.

  6. Our findings both genetically and functionally identify a novel disease-related molecule, FcgammaRIV, in an autoantibody-mediated disorder, which may be of importance for the development of novel targeted therapies.

  7. Two activating IgG receptors, FcgammaRIIIA and FcgammaRIV, expressed in mast cells are responsible for serum-induced passive arthritis in wild type mice.

  8. a variety of IgG2a- and IgG2b-dependent effector functions are impaired in the absence of Fcgr4 in models of autoimmunity and antibody-dependent cellular cytotoxicity.

  9. Identification of its gene

  10. Fc gammaRIV (Fc fragment of IgG, low affinity IIIa, receptor) is restricted to myeloid lineage cells, and binds to IgG2a and IgG2b with intermediate affinity.

  11. The length of the stalk region of the alpha-chain is an important determinant of Fc gamma receptor IIIA stability on the cell surface.

  12. FcgammaRIV requires association of the FcR gamma-chain for optimal expression and function on myeloid cells.

  13. The respective roles of FcgammaRI, FcgammaRIII, and FcgammaRIV in in the development of autoimmune hemolytic anemia were shown.

  14. Cooperative FcgammaRIV, FcgammaRIII, and FcgammaRI interactions mediated optimal lymphoma depletion by CD20 mAb in vivo.

  15. Fcgr4 is a mouse IgE receptor that resembles macrophage MS4A2 protein in humans and promotes IgE-induced lung inflammation.

  16. Required for both neutrophil influx and glomerular inflammation induced by switch-variant nephrotoxic IgG2a and IgG2b monoclonal antibodies.

  17. Results demonstrate a combined requirement for FcgammaRIII and FcgammaRIV in autoimmune injury, and identify the linker for activation of T cells adaptor as an integral component of linked FcgammaR and C5a activation to generate inflammation.

Fc Receptor, IgG, Low Affinity IV (FCGR4) Antigen Profile

Protein Summary

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.

Gene names and symbols associated with FCGR4

  • Fc receptor, IgG, low affinity IV (Fcgr4) antibody
  • 4833442P21Rik antibody
  • CD16-2 antibody
  • FcgammaRIV antibody
  • Fcgr3a antibody
  • FcgRIV antibody
  • Fcrl3 antibody

Protein level used designations for FCGR4

CD16-2 , Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gammaRIV , Fc receptor-like 3 , FcgammaRIV , low affinity immunoglobulin gamma Fc region receptor III-A , low affinity immunoglobulin gamma Fc region receptor IV

GENE ID SPECIES
246256 Mus musculus
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