anti-Fc Receptor, IgG, Low Affinity IV Antibodies

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578).

Data Quality
  • 2
  • 3
Type
  • 10
    Primary antibodies
Antigen
  • 10
Reactivity
  • 10
Application
  • 7
  • 4
  • 1
  • 1
  • 1
Host
  • 8
  • 2
Clonality
  • 8
  • 2
Clone
  • 5
  • 2
  • 1
Binding Specificity
  • 8
Conjugate
  • 5
  • 2
  • 1
  • 1
  • 1
Isotype
  • 8
  • 2
Format
  • 10
10 Products
ReactivityMouse (Murine)
Application FACS
Order details Cat. No. ABIN2692145
$300.88
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application FACS
Order details Cat. No. ABIN2213880
$365.59
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application FACS
Order details Cat. No. ABIN2692144
$365.59
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application FACS
Order details Cat. No. ABIN2478684
Pubmed
ISO
$372.71
0.1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityMouse (Murine)
Application IHC (fro), FACS
Order details Cat. No. ABIN2478683
Pubmed
ISO
$442.59
0.25 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityMouse (Murine)
Application ELISA
Order details Cat. No. ABIN2000187
ISO
$183.12
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application FACS
Order details Cat. No. ABIN2000185
ISO
$236.18
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application IHC (p), ELISA
Order details Cat. No. ABIN2000181
ISO
$312.53
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application ELISA, FACS, IF, IF/ICC
Order details Cat. No. ABIN2000183
ISO
$312.53
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityMouse (Murine)
Application ELISA
Order details Cat. No. ABIN2000189
ISO
$352.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
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Fc Receptor, IgG, Low Affinity IV (FCGR4) Antigen Profile

Protein Summary

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.

Gene names and symbols associated with FCGR4

  • Fc receptor, IgG, low affinity IV (Fcgr4) antibody
  • 4833442P21Rik antibody
  • CD16-2 antibody
  • FcgammaRIV antibody
  • Fcgr3a antibody
  • FcgRIV antibody
  • Fcrl3 antibody

Protein level used designations for FCGR4

CD16-2 , Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gammaRIV , Fc receptor-like 3 , FcgammaRIV , low affinity immunoglobulin gamma Fc region receptor III-A , low affinity immunoglobulin gamma Fc region receptor IV

GENE ID SPECIES
246256 Mus musculus
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