anti-Fibroblast Growth Factor 15 (FGF15) Antibodies

Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.. Additionally we are shipping FGF15 Kits (30) and FGF15 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FGF15 14170 O35622
FGF15    
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Top anti-FGF15 Antibodies at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Rat Kidney Tissue 100 μg Log in to see 13 to 16 Days
$418.00
Details
Mouse Sheep Un-conjugated IHC, IHC (fro)   100 μg Log in to see 11 to 14 Days
$1,145.83
Details
Rat Rabbit Biotin WB   100 μL Log in to see 11 to 14 Days
$625.17
Details
Rat Rabbit FITC WB   100 μL Log in to see 11 to 14 Days
$654.50
Details
Rat Rabbit Un-conjugated IC, IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days
$565.71
Details
Rat Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of recombinant Rat FGF15. IHC-P analysis of Rat Kidney Tissue, with DAB staining. 100 μg Log in to see 11 to 18 Days
$497.47
Details
Mouse Sheep Un-conjugated IHC   100 μg Log in to see 11 to 16 Days
$840.71
Details
Mouse Rabbit FITC ELISA   100 μg Log in to see 11 to 16 Days
$668.03
Details
Mouse Rabbit Biotin ELISA   100 μg Log in to see 11 to 16 Days
$668.03
Details
Mouse Rabbit HRP ELISA   100 μg Log in to see 11 to 16 Days
$668.03
Details

More Antibodies against FGF15 Interaction Partners

Mouse (Murine) Fibroblast Growth Factor 15 (FGF15) interaction partners

  1. Taken together, these results suggested that FGF19, through the anti-oxidative defense system, attenuated the development of diabetic cardiomyopathy and restored cardiac function.

  2. ileal FGF15/19 to hepatic FGFR4 axis is activated and promotes liver regeneration (LR) after partial hepatectomy (PH) in mice, supporting the potential of ileal FGF15/19 to hepatic FGFR4 axis-targeted therapy to enhance LR after PH

  3. FRS2alpha-mediated pathways are essential for the FGF15/FGF19-FGFR4 signaling axis to control bile acid homeostasis.

  4. Together, our results show that SuFu promotes cerebellar radial precursor differentiation to neurons. SuFu function is mediated in part by GLI3R and down-regulation of Fgf15 expression.

  5. Results show a reciprocal regulation of adiponectin and FGF19 gene expression in mice.

  6. Tumorigenicity was assessed in three mouse models (db/db, diet-induced obese, and multi-drug resistance 2 [Mdr2]-deficient) following continuous exposure to FGF19 or FGF15 via adeno-associated viral-mediated gene delivery.

  7. These data identify hypothalamic Fgf15 as a regulator of glucagon secretion.

  8. Intestinal sensing of highly elevated levels of conjugated bile acids in blood promotes FGF15 signaling, reducing hepatic bile acid synthesis and modulating bile acid transporters.

  9. Fgf15 is the sonic hedgehog downstream signal to control thalamic regionalization, neurogenesis, and neuronal differentiation by regulating the expression and mutual segregation of neurogenic and proneural regulatory genes.

  10. human microbiota was able to reduce the levels of tauro-beta-muricholic acid and induce expression of FXR target genes Fgf15 and Shp in ileum after long-term colonization. We show that a human microbiota can change BA composition and induce FXR signaling in colonized mice, but the levels of secondary BAs produced are lower than in mice colonized with a mouse microbiota

  11. FGF15 improves lipid homeostasis and reduces bile acid synthesis, but promotes fibrosis during the development of non-alcoholic steatohepatitis

  12. This study demonstrates that the FGF19-SHP-LSD1 axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components, including lipids, under nutrient-rich postprandial conditions.

  13. The elevation in circulating levels of adiponectin and Fgf15 led to normalized hepatic and serum levels of bile acids, limited hepatic accumulation of toxic bile, attenuated inflammation, and amelioration of liver injury in the ethanol-fed mNT knockout mice.

  14. This study reveals SHP as a global transcriptional partner of SREBP-2 in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19.

  15. we suggest that considerable mechanistic differences exist between humans and mice with regard to the nuclear receptors controlling the VitA-FGF15/19 axis.

  16. Ileal Fgf15 expression is a potent inhibitor of bile acid synthesis.

  17. Protective effects of farnesoid X receptor on hepatic lipid accumulation are mediated by hepatic FXR and are independent of intestinal FGF15 signaling.

  18. In mice with humanized livers human hepatocytes do not recognize FGF-15 produced by mouse intestine, resulting in up-regulation of bile acid synthesis enlargement of the bile acid pool, affecting the hepatostat.

  19. Intestinal PPARalpha-UDP- Glucuronyltransferases and downstream FXR-FGF15 signalling play vital roles in control of bile acid homeostasis and the pathological development of colitis.

  20. Sstudy shows an important contribution of ileal FGF15 to hepatocarcinogenesis in a clinically relevant mouse model where lack of Fgf15 resulted in reduced tumor burden and attenuated tumor progression.

FGF15 Antigen Profile

Protein Summary

Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.

Gene names and symbols associated with FGF15

  • fibroblast growth factor 15 (Fgf15) antibody
  • FGF19 antibody

Protein level used designations for FGF15

FGF-15

GENE ID SPECIES
14170 Mus musculus
Selected quality suppliers for anti-FGF15 (FGF15) Antibodies
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