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FLRT1 encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. Additionally we are shipping FLRT1 Antibodies (31) and FLRT1 Kits (2) and many more products for this protein.
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the phosphorylation state of FLRT1, which is itself FGFR1 (show FGFR1 Proteins) dependent, may play a critical role in the potentiation of FGFR1 (show FGFR1 Proteins) signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR (show FGFR2 Proteins)
Mice with deletions of FLRT1 and FLRT3 (show FLRT3 Proteins) adhesion molecules develop macroscopic sulci with preserved layered organization and radial glial morphology. Cortex folding in these mutants does not require progenitor cell amplification but is dependent on changes in neuron migration.
FLRT1 is expressed at brain compartmental boundaries in embryo
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain.
fibronectin leucine rich transmembrane protein 1
, leucine-rich repeat transmembrane protein FLRT1-like
, fibronectin-like domain-containing leucine-rich transmembrane protein 1
, leucine-rich repeat transmembrane protein FLRT1
, fibronectin leucine rich transmembrane protein 3