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FLRT2 encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. Additionally we are shipping FLRT2 Kits (23) and FLRT2 Antibodies (21) and many more products for this protein.
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Taken together, these results provide insights into the role of FLRT2 as a novel tumor suppressor in the breast, which is inactivated by hypermethylation during tumor development.
OPCML and FLRT2 were further validated in an independent cohort consisting of 20 low-Gleason and 33 high-Gleason tissues. We then compared patients with biochemical recurrence (n=70) vs. those without (n=86) in a third cohort, and they showed no difference in methylation at these DMR loci
The membrane protein, FLRT2, was identified as a novel autoantigen in systemic lupus erythematosus patients.
PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations
The observations propose that FLRT2 can regulate memory functions in the adulthood in a sex-specific manner and might thus contribute to further research on the mechanisms linking sexual dimorphism and cognition.
fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of the UNC5 receptor family for neurons, is unexpectedly expressed in endothelial cells specifically in the placental labyrinth.
Data show that Unc5 cell guidance receptor Unc5D controls Latrophilin3 (LPHN3)-FLRT protein FLRT2-mediated cell adhesion.
FLRT2 may exist in both membrane-bound and shed forms which interact with fibronectin in the ATDC5 chondroprogenitor cells.
findings provide evidence for a role of FLRT2 in enhancing cell proliferation and reducing intercellular adhesion during the early stages of chondrogenesis
mouse embryos lacking Flrt2 expression arrest at mid-gestation owing to cardiac insufficiency
Flrt2 was highly expressed initially in the cranial neural crest cells
FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome in embryo
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.
fibronectin leucine rich transmembrane protein 2
, leucine-rich repeat transmembrane protein FLRT2-like
, fibronectin-like domain-containing leucine-rich transmembrane protein 2
, leucine-rich repeat transmembrane protein FLRT2