anti-Flavin Containing Monooxygenase 3 (FMO3) Antibodies

Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds.

list all antibodies Gene Name GeneID UniProt
Anti-Human FMO3 FMO3 2328 P31513
Anti-Mouse FMO3 FMO3 14262 P97501
Anti-Rat FMO3 FMO3 84493 Q9EQ76
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Top anti-FMO3 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-FMO3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate FMO3 antibody - N-terminal region          Formalin Fixed Paraffin Embedded Tissue:  Human Liver Tissue    Observed Staining:  Cytoplasm in sinusoids of liver   Primary Antibody Concentration:  1:100    Secondary Antibody:  Donkey anti-Rabbit-Cy3    Secondary Antibody Concentration:  1:200    Magnification:  20X    Exposure Time:  0.5 - 2.0 sec 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FMO3 Antibody Titration:  0.2-1 ug/ml  Positive Control:  OVCAR-3 cell lysate FMO3 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells WB Suggested Anti-FMO3 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: OVCAR-3 cell lysate <br /> FMO3 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Fmo3 Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Immunocytochemistry/Immunofluorescence: FMO3 Antibody [NBP1-33583] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution. Western Blot: FMO3 Antibody [NBP1-33583] - Sample (50 ug of whole cell lysate) A: Mouse liver 7. 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image FMO3 antibody [N2C2], Internal detects FMO3 protein at cytosol on human normal liver by immunohistochemical analysis. Sample: Paraffin-embedded normal liver. FMO3 antibody [N2C2], Internal , dilution: 1:500. WB Image FMO3 antibody detects FMO3 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FMO3 antibody , diluted at a dilution of 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FMO3 Antibody (N-term) in MDA-MB231 cell line lysates (35 µg/lane). FMO3 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details

Top referenced anti-FMO3 Antibodies

  1. Cow (Bovine) Polyclonal FMO3 Primary Antibody for IHC, WB - ABIN2781862 : Ganti, Skapek, Zhang, Fuller, Wu, Billups, Breitfeld, Dalton, Meyer, Khoury: Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against FMO3 Interaction Partners

Human Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. Report developmental regulation of hepatic FMO3 expression.

  2. the involvement of flavin-containing monooxygenase-3 (FMO3) and cytochrome P450 (show CYP Antibodies) enzymes (CYPs) in Busulphan metabolic pathway, is reported.

  3. FMO3 protein abundance is significantly associated with age, gender, and genotype

  4. FMO3 Variant is associated with chronic kidney disease.

  5. Study tested the genetic effects of three FMOs genes (FMO1 (show FMO1 Antibodies), FMO3, and FMO6P) on nicotine dependence by performing targeted sequencing on 2,852 nicotine-dependent and nondependent smokers; identified significant association signals for gene FMO1 (show FMO1 Antibodies) and FMO6P

  6. The two FMO3 mutants were in close linkage disequilibrium and might play an important role in the pharmacokinetics of sulindac in Chinese healthy male volunteers.

  7. Olanzapine clearance was not affected by CYP2D6 (show CYP2D6 Antibodies) or FMO3 genotypes or smoking behavior as a single factor under the present conditions because olanzapine clearance is mediated by multiple enzymes involved in two major and one minor pathways

  8. Oxidative stress-responsive transcription factor NRF2 (show GABPA Antibodies) is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

  9. FMO3 gene polymorphism E158K is a significant predictor of predisposition to chronic heart disease in women.

  10. FMO3 is centrally involved in the pathogenesis of atherosclerosis by regulating cholesterol metabolism and insulin (show INS Antibodies) resistance. [Review]

Cow (Bovine) Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. Fishy off-flavor in cow's milk is caused by a nonsense mutation (R238X) in FMO3, found to be surprisingly common (q = 0.155) in the Swedish Red and White breed of dairy cattle.

Mouse (Murine) Flavin Containing Monooxygenase 3 (FMO3) interaction partners

  1. The suppression of FMO3 metabolism related to reversible S-nitrosyl modifications of iNOS (show NOS2 Antibodies)-derived NO in type 1 allergic mice.

  2. knockdown or genetic deletion of the TMAO-producing enzyme flavin-containing monooxygenase 3 (FMO3) confers protection against obesity in mice.

  3. FMO3 can contribute to the regulation of glucose metabolism in the liver by reducing lipid-induced endoplasmic reticulum stress and the expression of PEPCK (show PEPCK Antibodies), independently of insulin (show INS Antibodies) signal transduction.

  4. FMO3 is increased in obese/insulin (show INS Antibodies) resistant male mice and necessary for expression of FoxO1 (show FOXO1 Antibodies).

  5. Fmo3 expression and function plays a role in protecting the liver from acetaminophen-induced toxicity.

  6. a major role for FMO3 in modulating glucose and lipid homeostasis

  7. Report temporal changes in hepatic Fmo3 gene expression under different conditions all known to cause hepatic oxidative stress.

  8. Report selective modulation of hepatic cytochrome P450 (show CYP Antibodies) and flavin monooxygenase 3 expression during citrobacter rodentium infection in SCID (show PRKDC Antibodies) mice.

  9. The functional activity of Fmo3 was determined.

FMO3 Antigen Profile

Protein Summary

Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.

Gene names and symbols associated with FMO3

  • flavin containing monooxygenase 3 (FMO3) antibody
  • flavin containing monooxygenase 3 (fmo3) antibody
  • flavin containing monooxygenase 3 L homeolog (fmo3.L) antibody
  • flavin containing monooxygenase 3 (Fmo3) antibody
  • AW111792 antibody
  • dJ127D3.1 antibody
  • FM03 antibody
  • FMOII antibody
  • MGC107820 antibody
  • TMAU antibody

Protein level used designations for FMO3

dimethylaniline monooxygenase [N-oxide-forming] 3 , flavin containing monooxygenase 3 , FMO 3 , FMO II , FMO form 2 , dimethylaniline oxidase 3 , hepatic flavin-containing monooxygenase 3 , hepatic flavin-containing monooxygenase-3 , trimethylamine monooxygenase , flavin-containing monooxygenase 3 , FMO 1D1 , flavin-containing monooxygenase FMO3 , flavin-containing monooxygenase form 3

GENE ID SPECIES
100171678 Pongo abelii
548424 Xenopus (Silurana) tropicalis
447265 Xenopus laevis
2328 Homo sapiens
403603 Canis lupus familiaris
281167 Bos taurus
100009065 Oryctolagus cuniculus
14262 Mus musculus
84493 Rattus norvegicus
457505 Pan troglodytes
574244 Macaca mulatta
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