anti-Follistatin-Like 1 (FSTL1) Antibodies

FSTL1 encodes a protein with similarity to follistatin, an activin-binding protein. Additionally we are shipping FSTL1 Kits (66) and FSTL1 Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FSTL1 11167 Q12841
FSTL1 14314 Q62356
FSTL1 79210 Q62632
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Top anti-FSTL1 Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-FSTL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-FSTL1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184815 staining (0.5µg/ml) of Human Placenta lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184815 (0.3 µg/mL) staining of Placenta lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB FSTL1 Antibody (C-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FSTL1 antibody detected the FSTL1 protein (arrow). FSTL1 antibody (C-term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the FSTL1 antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Goat Un-conjugated WB   0.1 mg Log in to see Available
$462.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using FSTL1, antibody at 1:250 dilution. ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using FSTL1, antibody at 1:200 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of A549 cells using FSTL1 Antibody (C-term) Cat.-No AP51731PU-N (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma reacted with FSTL1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of A2780 cells, using FSTL1 antibody. ABIN6273118 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-FSTL1 Antibodies

  1. Human Polyclonal FSTL1 Primary Antibody for FACS, IHC (p) - ABIN654491 : Liu, Han, Yu, Ding, Ni, Liu, Hou, Li, Hou, Shen, Yin, Zhang, Thompson, Tan, Cao: A genetic polymorphism affects the risk and prognosis of renal cell carcinoma: association with follistatin-like protein 1 expression. in Scientific reports 2018 (PubMed)

  2. Human Polyclonal FSTL1 Primary Antibody for ELISA, WB - ABIN249639 : Tanaka, Ozaki, Osakada, Mori, Okubo, Nakao: Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases. in International immunology 1998 (PubMed)

More Antibodies against FSTL1 Interaction Partners

Human Follistatin-Like 1 (FSTL1) interaction partners

  1. In cultured human pulmonary artery smooth muscle cells, hypoxia-promoted cellular viability, DNA synthesis and migration were suppressed by exogenous FSTL1 but enhanced by small interfering RNA targeting FSTL1

  2. Study suggests that follistatin like 1 plays an important role in lung fibrosis, and may serve as a novel therapeutic target for treatment of silicosis.

  3. Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma.

  4. Study found that FSTL1 was downregulated in non-small cell lung cancer (NSCLC) cells. FSTL1 overexpression suppressed tumor cell proliferation, altered cell cycle and induced apoptosis in addition to inhibiting cell survival, migration and invasion. Altogether, results revealed the critical tumor-suppression function of FSTL1 in NSCLC progression, suggesting it as an important factor in NSCLC progression.

  5. Smad3 knockdown could restore the inhibition of cell proliferation induced by FSTL1 overexpression in MDAMB231FSTL1 cells, indicating that the antiproliferative effect of FSTL1 overexpression may be associated with Smad3 involved TGFbeta signaling pathway regulation. This study identified FSTL1 as an inhibitor of cell proliferation in MDAMB231 and 231BR cell lines

  6. Dendritic cell-mediated immunity was activated by FSTL1.

  7. Fstl1serves an important role in liver fibrosis and target deletion of Fstl1 attenuated HSCs activation through suppressing TGFbeta1/Smad3 signaling pathway.

  8. Results showed that: 1- FSTL-1 expression is localized to the stromal compartment of the pancreas; 2- FSTL-1 expression is reduced in pancreatic cancer, and 3- FSTL-1 inhibited pancreatic cancer cell proliferation.

  9. Data show that follistatin-like 1 (FSTL1) contributed to unfavorable post-surgical outcome of hepatocellular carcinoma (HCC) patients via inhibiting cell apoptosis.

  10. results indicate that rs1259293 is associated with an increased risk and unfavorable postoperative prognosis of renal cell carcinoma, possibly by down-regulating FSTL1 expression in renal tissues.

  11. Data provide evidence that FSTL1 modestly affects the proliferation of breast cancer cells and vascular endothelial cells. These findings improve the understanding of the functions of FSTL1 in breast cancer development and angiogenesis.

  12. knockdown of FSTL1 inhibited ASM cell proliferation and migration induced by PDGF-BB at least partially via inhibiting the activation of ERK and AKT. These results provide novel insight into the pathogenesis of airway remodeling in childhood asthma and FSTL1 may be a possible therapeutic strategy for the treatment of asthma.

  13. Fstl1 inhibited Smad1/5/8 phosphorylation by blocking the association between bone morphogenetic protein 4 and Bone Morphogenetic Protein Receptors, Type II via competitive binding to bone morphogenetic protein 4.

  14. Data show that follistatin like-1 (FSTL1) was frequently downregulated in nasopharyngeal carcinoma (NPC) cell lines and primary tumor biopsies by promoter hypermethylation.

  15. Results indicate the significance of follistatin-like protein 1 (FSTL1) in driving oncogenesis and metastasis in esophageal squamous cell carcinoma (ESCC) by coordinating NF-kappa B (NFkappaB) and bone morphogenetic proteins (BMP) pathway control.

  16. FSTL1 mRNA levels increased in castration-resistant prostate cancer in association with predominantly nuclear FSTL1.

  17. FSTL1 may induce epithelial mesenchymal transition and airway remodeling by activating autophagy.

  18. DROMs levels positively associated with Fstl1, Hemoglobin A1c and hsCRP levels.

  19. FSTL1 displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4/MyD88/NF-kappaB and MAPK signaling pathways.

  20. this study shows that 1) the expression of follistatin-like protein 1 is upregulated in rheumatoid arthritis patients; 2) miR-27a inhibits cell migration of rheumatoid arthritis synoviocytes by targeting follistatin-like protein 1 and restraining the TLR4/NFkappaB pathway

Mouse (Murine) Follistatin-Like 1 (FSTL1) interaction partners

  1. Haploinsufficiency of Fstl1 in mice contributed to an exacerbated hypoxia-induced Pulmonary hypertension, as demonstrated by increased right ventricular systolic pressure, pulmonary arterial muscularization and right ventricular hypertrophy index

  2. this study shows that FSTL-1 modulates IL-17 signaling via IL-17RC regulation in stromal cells

  3. FSTL1 may exert its actions through the modulation of Akt signaling.

  4. FSTL1 is a secreted osteoclastogenic factor that plays a critical role in osteoclast formation via the NF-kappaB and MAPKs signaling pathways.

  5. study indicates a pivotal role for Fstl1 in early stage of lung airway smooth muscle development

  6. This study reveals that Fstl1 is essential for the acute repair of the infarcted myocardium and that stimulation of early fibroblast activation is a novel function of Fstl1.

  7. Deletion of Fstl1 from the endocardial/endothelial lineage results in deformed mitral valves, which cause regurgitation, heart failure, and early cardiac death.

  8. A critical role for the Smad3-c-Jun pathway in the regulation of Fstl1.

  9. FSTL1 may induce epithelial mesenchymal transition and airway remodeling by activating autophagy.

  10. tightly spatial interaction of FSTL1 and BMP4 signaling plays an essential role in lung development

  11. a new role for FSTL1 in the development of radial glial scaffolds and the neuronal migration of upper-layer projection neurons, is reported.

  12. administration of Fstl1 induced airway remodeling and increased OSM, whereas administration of an anti-OSM Ab blocked the effect of Fstl1 on inducing airway remodeling, eosinophilic airway inflammation

  13. epicardial cells contain a potent cardiogenic activity identified as follistatin-like 1 (Fstl1)

  14. FSTL1 is a potent regulator of chondrocyte proliferation, differentiation and expression of extracellular matrix molecules.

  15. muscle-derived Fstl1 attenuates neointimal formation in response to arterial injury by suppressing smooth muscle cell proliferation through an AMPK-dependent mechanism

  16. functions in cardiorenal communication; lack of Fstl1 production by myocytes promotes glomerular and tubulointerstitial damage in the kidney

  17. Fstl1 is induced in response to lung injury and promotes the accumulation of myofibroblasts and subsequent fibrosis. These data suggest that Fstl1 may serve as a novel therapeutic target for treatment of progressive lung fibrosis.

  18. FSTL1 is elevated in various inflammatory conditions and decreased during the course of treatment. FSTL1 may therefore be a valuable biomarker for such diseases.

  19. This study is the first to describe a role for FSTL-1 in the development of Lyme arthritis and anti-Borrelia response.

  20. FSTL1 is a potential mediator of inflammation and insulin resistance in obesity.

FSTL1 Antigen Profile

Protein Summary

This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.

Gene names and symbols associated with FSTL1

  • follistatin like 1 (FSTL1) antibody
  • follistatin-like 1 (Fstl1) antibody
  • follistatin-like 1a (fstl1a) antibody
  • Follistatin-related protein 1 (fstl1) antibody
  • follistatin like 1 (Fstl1) antibody
  • follistatin-related protein 1 (LOC101909195) antibody
  • follistatin like 1 L homeolog (fstl1.L) antibody
  • AI316791 antibody
  • AW107808 antibody
  • DKFZp469P101 antibody
  • FLIK antibody
  • Frp antibody
  • FSL1 antibody
  • Fstl antibody
  • FSTL1 antibody
  • MIR198 antibody
  • TSC-36 antibody
  • wu:fc75h02 antibody
  • zgc:110703 antibody

Protein level used designations for FSTL1

follistatin-like protein 1 , follistatin-related protein 1 , TGF-beta-inducible protein TSC-36 , follistatin-like 1 , Follistatin-related protein 1 , Follistatin-like protein 1 , follistatin like 1 L homeolog

GENE ID SPECIES
11167 Homo sapiens
14314 Mus musculus
79210 Rattus norvegicus
325423 Danio rerio
395349 Gallus gallus
534482 Bos taurus
100172767 Pongo abelii
100195512 Salmo salar
100225571 Taeniopygia guttata
608384 Canis lupus familiaris
100720516 Cavia porcellus
101118330 Ovis aries
101909195 Bos taurus
594869 Xenopus laevis
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