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FSTL1 encodes a protein with similarity to follistatin, an activin-binding protein. Additionally we are shipping FSTL1 Kits (56) and FSTL1 Proteins (27) and many more products for this protein.
Showing 10 out of 107 products:
Human Polyclonal FSTL1 Primary Antibody for ELISA, WB - ABIN249639
Tanaka, Ozaki, Osakada, Mori, Okubo, Nakao: Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases. in International immunology 1998
results indicate that rs1259293 is associated with an increased risk and unfavorable postoperative prognosis of renal cell carcinoma (show MOK Antibodies), possibly by down-regulating FSTL1 expression in renal tissues.
Data provide evidence that FSTL1 modestly affects the proliferation of breast cancer cells and vascular endothelial cells. These findings improve the understanding of the functions of FSTL1 in breast cancer development and angiogenesis.
knockdown of FSTL1 inhibited ASM (show SMPD1 Antibodies) cell proliferation and migration induced by PDGF (show PDGFA Antibodies)-BB at least partially via inhibiting the activation of ERK (show EPHB2 Antibodies) and AKT (show AKT1 Antibodies). These results provide novel insight into the pathogenesis of airway remodeling in childhood asthma and FSTL1 may be a possible therapeutic strategy for the treatment of asthma.
Fstl1 inhibited Smad1 (show GARS Antibodies)/5/8 phosphorylation by blocking the association between bone morphogenetic protein 4 (show BMP4 Antibodies) and Bone Morphogenetic Protein Receptors, Type II via competitive binding to bone morphogenetic protein 4 (show BMP4 Antibodies).
Data show that follistatin like-1 (FSTL1) was frequently downregulated in nasopharyngeal carcinoma (NPC (show NPC1 Antibodies)) cell lines and primary tumor biopsies by promoter hypermethylation.
Results indicate the significance of follistatin-like protein 1 (FSTL1) in driving oncogenesis and metastasis in esophageal squamous cell carcinoma (ESCC) by coordinating NF-kappa B (NFkappaB (show NFKB1 Antibodies)) and bone morphogenetic proteins (BMP) pathway control.
FSTL1 mRNA levels increased in castration-resistant prostate cancer in association with predominantly nuclear FSTL1.
FSTL1 may induce epithelial mesenchymal transition and airway remodeling by activating autophagy.
DROMs levels positively associated with Fstl1, Hemoglobin A1c and hsCRP levels.
FSTL1 displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) and MAPK (show MAPK1 Antibodies) signaling pathways.
FSTL1 is a secreted osteoclastogenic factor that plays a critical role in osteoclast formation via the NF-kappaB (show NFKB1 Antibodies) and MAPKs signaling pathways.
study indicates a pivotal role for Fstl1 in early stage of lung airway smooth muscle development
This study reveals that Fstl1 is essential for the acute repair of the infarcted myocardium and that stimulation of early fibroblast activation is a novel function of Fstl1.
Deletion of Fstl1 from the endocardial/endothelial lineage results in deformed mitral valves, which cause regurgitation, heart failure, and early cardiac death.
A critical role for the Smad3 (show SMAD3 Antibodies)-c-Jun (show JUN Antibodies) pathway in the regulation of Fstl1.
tightly spatial interaction of FSTL1 and BMP4 (show BMP4 Antibodies) signaling plays an essential role in lung development
a new role for FSTL1 in the development of radial glial scaffolds and the neuronal migration of upper-layer projection neurons, is reported.
administration of Fstl1 induced airway remodeling and increased OSM (show OSM Antibodies), whereas administration of an anti-OSM (show OSM Antibodies) Ab blocked the effect of Fstl1 on inducing airway remodeling, eosinophilic airway inflammation
epicardial cells contain a potent cardiogenic activity identified as follistatin-like 1 (Fstl1)
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.
follistatin-like protein 1
, follistatin-related protein 1
, TGF-beta-inducible protein TSC-36
, follistatin-like 1
, Follistatin-related protein 1
, follistatin like 1 L homeolog