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FOXD4 encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. Additionally we are shipping FOXD4 Proteins (4) and and many more products for this protein.
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FOXd4 encodes forkhead box D4 protein.
The W148R mutation disrupts an extremely highly conserved tryptophan residue in the forkhead domain of FOXD4, possibly resulting in reduced DNA binding capacity and altered transcriptional activity.
We demonstrate that mouse and human homologs of Foxd4l1 have similar functional domains compared to the frog protein, as well as conserved transcriptional activities when expressed in Xenopus embryos and blastomere explants.
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality.
forkhead box D4
, forkhead box protein D4
, forkhead, Drosophila, homolog-like 9
, forkhead-related activator 5
, forkhead-related protein FKHL9
, forkhead-related transcription factor 5
, myeloid factor-alpha
, forkhead homolog 2
, transcription factor FKH-2
, hepatocyte nuclear factor 3 forkhead homolog 6