anti-Formin Binding Protein 1-Like (FNBP1L) Antibodies

The protein encoded by FNBP1L binds to both CDC42 and N-WASP. Additionally we are shipping FNBP1L Proteins (4) and FNBP1L Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FNBP1L 54874 Q5T0N5
FNBP1L 214459 Q8K012
FNBP1L 310839 Q2HWF0
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Top anti-FNBP1L Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FNBP1L Antibody  in mouse lung tissue lysates (35ug/lane). This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg 11 to 14 Days
$616.00
Details
Human Rabbit Un-conjugated WB 0.1 mg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg 12 to 14 Days
$686.14
Details
Human Mouse Un-conjugated ELISA, WB FNBP1L monoclonal antibody (M01), clone 1E6. Western Blot analysis of FNBP1L expression in HepG2. Detection limit for recombinant GST tagged FNBP1L is 1 ng/ml as a capture antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details

Top referenced anti-FNBP1L Antibodies

  1. Human Polyclonal FNBP1L Primary Antibody for IHC (p), WB - ABIN541653 : Ho, Rohatgi, Lebensohn, Le Ma, Li, Gygi, Kirschner: Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. in Cell 2004 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal FNBP1L Primary Antibody for IHC (p), WB - ABIN541651 : Kakimoto, Katoh, Negishi: Regulation of neuronal morphology by Toca-1, an F-BAR/EFC protein that induces plasma membrane invagination. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against FNBP1L Interaction Partners

Human Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. During Shigella flexneri infection host protein Toca-1 precipitate not only the Shigella type 3 secreted effector protein IcsB, but also the type 3 secreted proteins OspC3, IpgD and IpaB. In infected cells, OspC3-mediated restriction of IL-18 production does not require the interaction with Toca-1.

  2. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

  3. Loss of p53 tumor suppressor function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.

  4. GWAS results show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts; FNBP1L was also significantly associated with childhood intelligence

  5. findings suggest that Toca-1 functions at an early step in the dissemination of metastatic breast tumor cells; taken together, results identify Toca-1 as a proinvasive protein in breast adenocarcinoma

  6. Toca-1 knockdown cells also display a significant defect in EGF-induced motility and invasiveness.

  7. Cdc42 may influence endocytic membrane trafficking by regulating the formation and activity of the Toca-1/N-WASP complex.

  8. Toca-1 promotes actin nucleation by activating the N-WASP-WIP/CR16 complex, the predominant form of N-WASP in cells.

  9. a vesicle trafficking regulator Toca-1 regulates different aspects of neuronal morphology from N-WASP

  10. We show that actin tail initiation by S. flexneri requires Toca-1 for the conversion of N-WASP from a closed inactive conformation to an open active one.

  11. the Toca-1-N-WASP complex can link filopodial formation to endocytosis

  12. Human FNBP1L binds the autophagy protein Atg3 and is required for autophagy of Salmonella Typhimurium in epithelial cells

Mouse (Murine) Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. Toca-1(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP.

Xenopus laevis Formin Binding Protein 1-Like (FNBP1L) interaction partners

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

FNBP1L Antigen Profile

Protein Summary

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with FNBP1L

  • formin binding protein 1 like (FNBP1L) antibody
  • formin binding protein 1-like (Fnbp1l) antibody
  • formin binding protein 1-like (fnbp1l) antibody
  • formin binding protein 1 like (fnbp1l) antibody
  • formin binding protein 1 like L homeolog (fnbp1l.L) antibody
  • formin binding protein 1 like S homeolog (fnbp1l.S) antibody
  • 2610318I01Rik antibody
  • AW548221 antibody
  • C1orf39 antibody
  • fnbp1l antibody
  • MGC132162 antibody
  • RGD1305386 antibody
  • toca-1 antibody
  • toca1 antibody
  • zgc:100923 antibody

Protein level used designations for FNBP1L

formin-binding protein 1-like , toca-1 , transducer of Cdc42-dependent actin assembly 1 , transducer of Cdc42-dependent actin assembly protein 1 , Cdc42 effector , formin binding protein 1-like , transducer of Cdc42-dependent actin assembly-1 , Transducer of Cdc42-dependent actin assembly protein 1

GENE ID SPECIES
54874 Homo sapiens
214459 Mus musculus
310839 Rattus norvegicus
424495 Gallus gallus
445240 Danio rerio
448740 Xenopus (Silurana) tropicalis
469385 Pan troglodytes
479942 Canis lupus familiaris
616665 Bos taurus
713578 Macaca mulatta
735241 Xenopus laevis
100032840 Monodelphis domestica
100059052 Equus caballus
100077332 Ornithorhynchus anatinus
100157977 Sus scrofa
100338578 Oryctolagus cuniculus
100405015 Callithrix jacchus
100448000 Pongo abelii
100476131 Ailuropoda melanoleuca
100559983 Anolis carolinensis
446802 Xenopus laevis
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