anti-Formin Homology 2 Domain Containing 1 (FHOD1) Antibodies

Human Formin Homology 2 Domain Containing 1 (FHOD1) interaction partners

1. The functional integrity of lamin (show LMNA Antibodies) and nesprin-1 (show SYNE1 Antibodies) is thus required to modulate the FHOD1 activity and the inside-out mechanical coupling that tunes the cell internal stiffness to match that of its soft, physiological-like environment.

2. results suggest that FHOD1 participates in key cellular processes that are dysregulated in malignancy

3. FHOD1 and INF2 (show INF2 Antibodies) are novel regulators of inter- and intra-structural contractility of podosomes.

4. Immunostaining of sections of hearts with both anti-FHOD1 antibodies confirmed the presence of FHOD1 in intercalated discs and double immunostaining demonstrated its colocalisation with cadherin, plakoglobin (show JUP Antibodies) and shifted localization to connexin43 (show GJA1 Antibodies).

5. FHOD1 promotes formation of short actin filaments and transiently associates with transverse arcs providing tight temporal and spatial control of the formation and turnover of transverse arcs into mature ventral stress fibers during dynamic cell behavior.

6. the diaphanous formin (show FMN1 Antibodies) FHOD1 as an interaction partner of N2G

7. FHOD1 participates in cytoskeletal changes in epithelial-mesenchymal transition.

8. Cdh1 (show CDH1 Antibodies) contributes to spatiotemporal organization of AurB (show AURKB Antibodies) activity, and organization of FHOD1 activity by AurB (show AURKB Antibodies) contributes to daughter cell spreading after mitosis.

9. FHOD1 stabilizes actin filaments by protecting barbed ends from depolymerization with its dimeric FH2 domain, whereas the region N-terminal to the FH1 domain mediates F-actin bundling by simultaneously binding to the sides of adjacent F-actin filaments.

10. SIRPalpha/CD172a (show SIRPA Antibodies) and FHOD1 are unique markers of littoral cells, a recently evolved major cell population of red pulp of human spleen.

Mouse (Murine) Formin Homology 2 Domain Containing 1 (FHOD1) interaction partners

1. FHOD1 is regulated by ROCK for cytoplasm actin assembly and spindle migration during mouse oocyte meiosis.

2. We report here that a major formin in mouse fibroblasts, FHOD1, is recruited to integrin clusters, resulting in actin assembly.

3. Letter: G-protein coupled and ITAM receptor regulation of the formin (show FMN1 Antibodies) FHOD1 through Rho kinase (show ROCK2 Antibodies) in platelets.