Formyl Peptide Receptor 1 (FPR1) ELISA Kits

FPR1 encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. Additionally we are shipping FPR1 Antibodies (119) and FPR1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FPR1 2357 P21462
FPR1 14293 P33766
Anti-Rat FPR1 FPR1 292409  
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Top FPR1 ELISA Kits at antibodies-online.com

Showing 2 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$700.00
Details
Mouse < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details

More ELISA Kits for FPR1 Interaction Partners

Human Formyl Peptide Receptor 1 (FPR1) interaction partners

  1. Results show high expression of FPR1 in triple-negative breast cancer (TNBC) and in lymph node metastasis. This expression level was positively correlated with that of AnxA1 in primary tumors. The autocrine activation of FPR1 by AnxA1 might be a pivotal target for TNBC.

  2. FPR1 mRNA levels in whole blood can predict the presence of lung cancer. Using this as a reflex test for positive lung cancer screening computed tomography scans has the potential to increase the positive predictive value.

  3. To develop enzyme-resistant analogues, we applied here the Retro-Inverso (RI) approach, whereby the topology of the side chains is maintained by inverting the sequence of the peptide and the chirality of all residues. Molecular dynamics suggests that peptide RI-3 adopts the turn structure typical of uPAR-FPR1 antagonists

  4. Authors found that the co-expression of uPAR and FPR1 confers to A375 and M14 melanoma cells a clear-cut capability to move towards chemotactic gradients, to cross extracellular matrix and endothelial monolayers. FPR1 activity is required, as cell migration and invasion were abrogated by receptor desensitization.

  5. Taken together, our results suggest that intracellular FPR in naive CD4 T cells and surface FPRs in activated CD4 T cells might regulate immune responses by regulating CD4 T cell activity.

  6. the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases

  7. The data demonstrate that FPR1 is involved in neuroblastoma development and could represent a therapy option for the treatment of neuroblastoma.

  8. FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2.

  9. Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.

  10. The inhibitory function of oxidant sensing by TRPM2 requires the oxidation of Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 internalization and signaling inhibition

  11. FPR1 expression is significantly upregulated in human masticatory mucosa during wound healing

  12. FAM19A4 is a novel ligand of formyl peptide receptor 1.

  13. The authors describe here the activation of isolated human blood neutrophils by TcdB and, moreover, by toxin fragments generated by limited proteolytical digestion via the FPR1 receptor.

  14. these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.

  15. Data suggest that formyl peptide receptor 1 (FPR1) stimulation may represent a novel therapeutic approach to counteract tumor angiogenesis.

  16. a pepducin designed to target FPR1 was found to hijack FPR2 and potently inhibit neutrophil functions

  17. the co-upregulated expression of mast cell chymase and ANXA1-FPR1 system in ectopic endometrium suggests their involvement in the development of endometriotic lesions.

  18. FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative age-related macular degeneration and polypoidal choroidal vasculopathy .

  19. These results demonstrate that a necroptosis pathway, likely mediated by annexin 1 acting through the FPR1 receptor, contributes to Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis.

  20. A low FPR1/beta1 integrin co-localization was observed.

Mouse (Murine) Formyl Peptide Receptor 1 (FPR1) interaction partners

  1. Study showed significantly increased expression of FPR1 and FPR2, during differentiation of neural stem cells (NSCs). The activation of FPRs promotes NSCs to differentiate into neurons with more primary neurites and branch points and longer neurites per cell. Meanwhile, this activation also inhibits the differentiation of NSCs into astrocytes.

  2. FPR1-deficient mice showed a slight but significant decrease of demyelination in the corpus callosum and reduced glial cell activation.

  3. the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases

  4. Intravital TPLSM revealed that formyl-peptide-FPR1 signaling is responsible for regulating neutrophil chemotaxis to allow migration into the necrotic area in hepatic ischemia-reperfusion injury

  5. FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2.

  6. Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.

  7. Blocking of FPR1 completely abrogated the fMet-Leu-Phe-, gliadin- and synthetic peptide-induced migration.

  8. these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.

  9. Ovalbumininduced airway inflammation is mediated by upregulation of the TLR2/MyD88/NFkappaB signaling pathway and inhibition of LXA4R.

  10. Deficiency of formyl peptide receptor 1 is associated with increased inflammation and enhanced liver injury after LPS-stimulation

  11. Fpr1/2 are critical for normal healing of the sterile skin wound by mediating the first wave of neutrophil infiltration.

  12. these findings identify a novel role of FPR1 as pattern recognition receptors for perceiving the enteric microbiota that promotes repair of mucosal wounds via generation of reactive oxygen species from the enterocyte NOX1.

  13. FPR1 and FPR2 play an important role in the innate immune responses against Streptococcus pneumoniae within the central nervous system and the lack of the receptors leads to a dysregulation of the inflammatory response compared with wild-type mice.

  14. mediates neutrophil recruitment in acute lung injury

  15. Further, these results reveal Fpr1 as a major mediator of host commensal interaction during dysbiosis.

  16. The mechanism involved impaired early neutrophil recruitment to the liver with Fpr1 being sole receptor for neutrophils to sense Listeria chemoattractant signals and for production of bactericidal superoxide.

  17. findings may have clinical significance because current smokers and subjects with emphysema showed increased FPR expression in bronchoalveolar fluids and on peripheral neutrophils

  18. Neutrophil migration into the inflamed mouse colon does not depend on FPR1, but FPR1 contributes in other pathological mechanisms that are harmful during acute inflammation but are protective during chronic inflammation.

  19. Enteric commensal bacteria induce extracellular signal-regulated kinase pathway signaling via formyl peptide receptor-dependent redox modulation of dual specific phosphatase 3

  20. Fpr1 has a role in modulation of anxiety-like behavior and fear memory by regulating glucocorticoid production

FPR1 Antigen Profile

Antigen Summary

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.

Gene names and symbols associated with FPR1

  • formyl peptide receptor 1 (FPR1) antibody
  • formyl peptide receptor 1 (Fpr1) antibody
  • fMLF-R antibody
  • FMLP antibody
  • FPR antibody
  • FPR1 antibody
  • LXA4R antibody

Protein level used designations for FPR1

N-formylpeptide chemoattractant receptor , fMLP receptor , fMet-Leu-Phe receptor , N-formyl peptide receptor , lipoxin A4 receptor

GENE ID SPECIES
2357 Homo sapiens
14293 Mus musculus
292409 Rattus norvegicus
456254 Pan troglodytes
100443662 Pongo abelii
100009153 Oryctolagus cuniculus
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