Formyl Peptide Receptor 3 Proteins (FPR3)

Low affinity receptor for N-formyl-methionyl peptides. Additionally we are shipping FPR3 Antibodies (95) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat FPR3 FPR3 292413  
FPR3 2359 P25089
FPR3 14294 O08790
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Top FPR3 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
Yeast Yeast His tag   1 mg 60 to 71 Days
Wheat germ Human Un-conjugated   2 μg 11 to 12 Days

FPR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Formyl Peptide Receptor 3 (FPR3) Interaction Partners

Human Formyl Peptide Receptor 3 (FPR3) interaction partners

  1. These findings provide evidence for defective FPR2/3 and annexin A1 expressions that, associated with decreased M2a polarization, might be involved in the development of cigarette smoking induced persistent airflow limitation in chronic obstructive pulmonary disease.

  2. Taken together, our results suggest that intracellular FPR in naive CD4 T cells and surface FPRs in activated CD4 T cells might regulate immune responses by regulating CD4 T cell activity.

  3. The demonstrated proper folding and functionality of the cell-free produced human FPR3 opens a new avenue for the fast and efficient generation of human FPRs (and even other GPCRs) for structural and functional analysis.

  4. The H. pylori-derived peptide Hp(2-20) stimulated eosinophil migration through the engagement of FPR2 and FPR3, and also induced production of VEGF-A and TGF-beta, two key mediators of tissue remodelling.

  5. transcriptional variations of FPR3 occur by an alternative promoter during primate evolution.

  6. F2L peptide, derived from the processing of nanomolar concentrations of heme-binding protein (HEBP)1, is active on FPR3 and able to induce recruitment of FPR3-expressing monocytes, macrophages, and mouse neutrophils

  7. N-formyl peptide receptor 3 (FPR3) departs from the homologous FPR2/ALX receptor with regard to the major processes governing chemoattractant receptor regulation, expression at the cell surface, and phosphorylation.

  8. Results show that uPAR expression regulates the adhesive and migratory ability of CXCR4-expressing cells through a mechanism involving fMLP receptors and alpha-v integrins.

  9. Human dendritic cells express functional FPRL2 throughout maturation. FPRL2 & its endogenous ligand may be involved in regulating DC trafficking during Ag uptake & processing s well as the T-cell-stimulating phase of the immune responses.

  10. investigated the direct effect of LXA4 as well as the effect on agonist-induced biological responses using transfected HL-60 cells expressing FPR, FPRL1 or FPRL2

  11. an annexin 1 peptide can activate FPR, FPRL1, and FPRL2; results indicate that annexin 1 participates in regulating leukocyte emigration into inflamed tissue by activating and desensitizing different receptors of the FPR family.

  12. Results show that humanin (HN) acts as a ligand for formyl peptide receptor-like 1 (FPRL1) and 2 (FPRL2).

  13. Activation of FPRL2 inhibits lipopolysaccharide-induced dendritic cell maturation.

  14. However, F2L inhibits formyl peptide receptor (FPR) and FPRL1 activities, resulting in the inhibition of intracellular calcium increases, and superoxide generation induced by N-formyl-Met-Leu-Phe, MMK-1, or Trp-Lys-Tyr-Met-Val-d-Met in neutrophils.

  15. FPRL2 is expressed and functional in macrophages differentiated from monocytes in vitro in different conditions

  16. Human monocytes express FPR1, FPR2, and FPR3; human neutrophils express FPR1 and FPR2, but not FPR3.

Mouse (Murine) Formyl Peptide Receptor 3 (FPR3) interaction partners

  1. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance

  2. antagonist pretreatment or gene silencing of the RvD1 receptor, ALX/FPR2, abrogated the anti-inflammatory and pro-resolving actions of RvD1. These data indicate that RvD1 ameliorates IR-induced liver injury, and this protection is associated with enhancement of M2 polarization and efferocytosis via ALX/FPR2 activation

  3. The genome of at least 19 strains encodes a non-functional Fpr3 variant, whereas at least 13 other strains express an intact receptor. These results provide a foundation for understanding the in vivo function of Fpr3.

  4. Compared with wild-type mice, Fpr2/3(-/-) animals exhibited exacerbation of disease severity, including hypothermia and cardiac dysfunction.

  5. During ischemia, neutrophil Fpr2/3 controls platelet/neutrophil aggregates with the rapid generation of circulating LXA4, which in turn modulates downstream vascular inflammatory responses evident during the reperfusion phase.

  6. the ligand profile of mFpr-rs1 is consistent with a role in vomeronasal pathogen sensing

  7. lipoxin A(4)mediated the restoration of homeostasis of inflammation perpetuated by blocking COX-2 activity and PGE(2) production during resolution of collagen-induced arthritis

  8. This homologue receptor shows 89% sequence identity with murine lipoxin A4 receptor cDNA and functionally responds to LXA4 as a ligand.

  9. Leukocyte antiadhesive and anti-inflammatory actions of annexin 1 involve this receptor.

FPR3 Protein Profile

Protein Summary

Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states.

Gene names and symbols associated with FPR3

  • formyl peptide receptor 3 (Fpr3)
  • formyl peptide receptor 3 (FPR3)
  • ALX protein
  • FML2_HUMAN protein
  • FMLP-R-II protein
  • FMLPY protein
  • Fpr-rs1 protein
  • Fpr-s1 protein
  • FPRH1 protein
  • FPRH2 protein
  • Fprl1 protein
  • FPRL2 protein
  • LXA4-R protein
  • Lxa4r protein
  • RGD1566044 protein
  • RMLP-R-I protein

Protein level used designations for FPR3

FMLP-R-II , FMLP-related receptor II , N-formyl peptide receptor 3 , formyl peptide receptor-like 2 , FMLP-R-I , FMLP-related receptor I , LXA4 receptor , N-formyl peptide receptor 2 , N-formylpeptide receptor-like 1 , formyl peptide receptor-like 1 , formyl peptide receptor-related sequence 1 , lipoxin A4 receptor , N-formyl peptide receptor-like 2 receptor

292413 Rattus norvegicus
2359 Homo sapiens
14294 Mus musculus
719802 Macaca mulatta
468979 Pan troglodytes
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