anti-Free Fatty Acid Receptor 3 (FFAR3) Antibodies

Receptor for short chain fatty acids.

list all antibodies Gene Name GeneID UniProt
Anti-Human FFAR3 FFAR3 2865 O14843
Anti-Rat FFAR3 FFAR3 365228  
Anti-Mouse FFAR3 FFAR3 233080 Q3UFD7
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Top anti-FFAR3 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of GPR41 expression in HeLa (A), Raw264.7 (B), H9C2 (C), rat Liver (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using FFAR3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-FFAR3 antibody  ABIN1048598 IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FFAR3 antibody  ABIN1048598 IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of FFAR3 Antibody (C-term) (ABIN651415) in Jurkat cell line lysates (35 µg/lane).FFAR3 (arrow) was detected using the purified polyclonal antibody. FFAR3 Antibody (C-term) (ABIN651415) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: GPR41 Antibody [NBP2-14014] Staining of human rectum shows strong cytoplasmic positivity in glandular cells. Immunohistochemistry-Paraffin: FFAR3/GPR41 Antibody  - Staining of human small intestine shows strong membranous and cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 12 to 14 Days
$685.40
Details
Human Rabbit Un-conjugated ELISA, IF, WB   100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit FITC FACS, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

Top referenced anti-FFAR3 Antibodies

  1. Human Polyclonal FFAR3 Primary Antibody for IF, ELISA - ABIN1535676 : Nøhr, Egerod, Christiansen, Gille, Offermanns, Schwartz, Møller: Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia. in Neuroscience 2015 (PubMed)

More Antibodies against FFAR3 Interaction Partners

Cow (Bovine) Free Fatty Acid Receptor 3 (FFAR3) interaction partners

  1. An inverse regulation of FFAR2 (show FFAR2 Antibodies) and FFAR3 expression over time and both receptors also showed an inverse mRNA abundance as induced by different portions of concentrate. Thus, indicating divergent nutrient sensing of both receptors in adipose tissues (AT) during the transition period.

  2. GPR41 gene contains 3 exons and its transcription is initiated at 2 leader exons, generating 2 GPR41 mRNA variants differing in the 5' untranslated region

Human Free Fatty Acid Receptor 3 (FFAR3) interaction partners

  1. Data suggest that cytokines TNFalpha (show TNF Antibodies) and interleukin-1b markedly reduce GPR120/FFAR4 (show O3FAR1 Antibodies) expression in adipocytes; in contrast, these cytokines induce expression of GPR84 (show GPR84 Antibodies) and GPR41/FFAR3 in adipocytes. These studies were conducted in adipocytes cultured from subcutaneous adipose tissue. (GPR (show ALDH18A1 Antibodies) = G-protein coupled receptor (show ADRA1A Antibodies); FFAR = free fatty acid receptor)

  2. a single dose of soluble fibre was able to significantly reduce airway inflammation in stable asthma by downregulating GPR43 (show FFAR2 Antibodies) and GPR41

  3. Short-chain fatty acids lowered TNF-alpha (show TNF Antibodies)-induced MCP-1 (show CCL2 Antibodies) expression by reducing phosphorylation of p38 MAPK (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) in a GPR41/GRP43-dependent manner in renal cortical epithelial cells.

  4. Our data suggest that GPR42 be reclassified as a functioning gene and that recognition of sequence and copy number polymorphism of the FFAR3/GPR42 complex be considered during genetic and pharmacological investigation of these receptors.

  5. FFAR3 is expressed in pancreatic beta cells and mediates an inhibition of insulin (show INS Antibodies) secretion by coupling to Gi-type G proteins.

  6. a significant correlation between a higher body mass index and lower methylation in the promoter region of FFAR3 in type 2 diabetes and obesity patients

  7. Propionate-stimulated GPR41 strongly coupled to ERK1/2 activation, while the coupling of linoleic acid-activated GPR40 (show FFAR1 Antibodies) and acetate-activated GPR43 (show FFAR2 Antibodies) was weaker.

  8. GPR41 activation inhibits histone acetylation and cell growth.

  9. GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 (show FFAR1 Antibodies) and GPR41 proteins

  10. Selective orthosteric free fatty acid receptor 2 (show FFAR2 Antibodies) (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

Mouse (Murine) Free Fatty Acid Receptor 3 (FFAR3) interaction partners

  1. Gpr41 KO mice have hypertension of a vascular origin.

  2. the maternal microbiome influences Treg differentiation in the thymus of offspring through GPR41-mediated Aire (show AIRE Antibodies) expression

  3. that GPR41 and its ligands, short-chain fatty acids, may play an important role in the fine-tuning of insulin (show INS Antibodies) secretion in fed and fasting states

  4. Pharmacological and knockdown experiments showed that activation of sympathetic neurons by SCFA propionate involves SCFA receptor GPR41 linking to Gbetagamma-PLCbeta3-ERK1/2-synapsin 2 (show SYN2 Antibodies)

  5. mediates beta cell glucose stimulated insulin (show INS Antibodies) secretion through Galphai/o sensitive pathway

  6. Results indicate that FFAR3 is expressed on postganglionic sympathetic and sensory neurons in both the autonomic and somatic peripheral nervous system

  7. FFAR3 is expressed in pancreatic beta cells and mediates an inhibition of insulin (show INS Antibodies) secretion by coupling to Gi-type G proteins.

  8. Data from transgenic mice suggest that Ffar3/Gpr41 and Ffar2/Gpr43 (show FFAR2 Antibodies) both act as sensors for short-chain fatty acids in enteroendocrine cells; Ffar3/Gpr41 appears to play this role alone in enteric neurons and Ffar2/Gpr43 (show FFAR2 Antibodies) alone in enteric leukocytes.

  9. Short-chain fatty acids activate GPR41 and on intestinal epithelial cells, leading to mitogen-activated protein kinase (show MAPK1 Antibodies) signaling and rapid production of chemokines and cytokines. These pathways mediate protective immunity and tissue inflammation in mice.

  10. GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 (show FFAR1 Antibodies) and GPR41 proteins

FFAR3 Antigen Profile

Protein Summary

Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.

Gene names and symbols associated with FFAR3

  • free fatty acid receptor 3 (LOC455946) antibody
  • free fatty acid receptor 3 (FFAR3) antibody
  • free fatty acid receptor 3 (LOC100600134) antibody
  • free fatty acid receptor 3 (Ffar3) antibody
  • FFA3R antibody
  • Gm478 antibody
  • Gpr41 antibody

Protein level used designations for FFAR3

free fatty acid receptor 3 , G protein-coupled receptor 41 , G-protein coupled receptor 41 , putative G protein-coupled receptor GPR41

GENE ID SPECIES
455946 Pan troglodytes
527517 Bos taurus
612659 Canis lupus familiaris
708732 Macaca mulatta
100600134 Nomascus leucogenys
2865 Homo sapiens
365228 Rattus norvegicus
233080 Mus musculus
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